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Biomedical subjects

F M Debruyne

Publications and source records attributed to F M Debruyne.

At least 487 records · Page 27Linked to original sources

Has the suprapubic suspension operation any influence on the urethral pressure profile?

The urethral pressure profiles of 35 patients suffering from stress incontinence before and after suprapubic suspension operations have been analysed. Irrespective of the post-operative result there were no significant changes in the various characteristics of the pressure profile. The results suggest that a suspension operation for stress incontinence has no direct effect on the sphincteric urethral mechanism but places the urethra in a higher position where it can be affected by increases in intra-abdominal pressure.

Adult↗

Anterior vaginal repair, cause of troublesome voiding disorders?

Clinical experience and urodynamic observations in 85 female patients with voiding disorders after anterior vaginal repair are presented. Iatrogenic or persistent urinary stress incontinence (72%), irritable trigone syndrome (48%), bladder outlet obstruction (40%), unstable bladder (25%) and recurrent cystitis (23.5%) were the most frequent findings. Also, 5 cases of urogenital fistula and 2 cases of loss of a great part of the urethra were noted. Attempts to cure these complications with different pharmacologic agents and/or surgical methods were often disappointing.

Female↗

Successful pregnancy after renal transplantation in a patient with a urinary diversion.

A successful pregnancy is reported in a patient following renal transplantation and urinary diversion. The second half of pregnancy was complicated by hypertension, impaired renal function and obstruction of the ureter in the 35th wk. The latter complication required early termination of pregnancy by cesarean section. A healthy infant was delivered who survived without complications. Maternal renal function returned to pre-pregnancy levels following delivery.

Adult↗

Has bromocriptine a place in the treatment of the unstable bladder?

A clinical study of bromocriptine in the treatment of 18 patients with an unstable bladder is reported. All patients had previously received drug therapy and/or vesical distension, without success. Ten of the 18 patients had side-effects, and 2 of these did not complete the study. Only 2 patients noted moderate improvement in their urinary symptoms. Bromocriptine appears to be of little value in the treatment of the unstable bladder.

Administration, Oral↗

Uretero-neo-cystostomy in renal transplantation. Is an antireflux mechanism mandatory?

We report a retrospective analysis of 120 kidney transplantations in which a simple end-to-end ureteric implantation in the bladder without antireflux mechanism was made. From this study no greater incidence of vesico-ureteric reflux could be demonstrated and, even when present, reflux neither interfered with graft function nor caused an increased incidence of recurrent urinary tract infections. The incidence of other urological complications (leakage, obstruction) being equal, this very simple technique yielded in our hands the best results and we recommend its use in kidney transplantation.

Humans↗

Epidermoid cyst of the testis.

Surgical exploration of a mass in the right testis revealed an epidermoid cyst. In the literature some controversy exists on surgical treatment of this lesion. Orchiectomy seems to be recommended although several patients treated by simple enucleation had an uneventful follow-up from 6 to 15 years.

Adult↗

Intrarenal arteriovenous fistula following renal allograft biopsy.

Arteriovenous fistulae in renal allograft are rarely mentioned in papers dealing with vascular complications after renal transplantations. 2 cases of such central fistulae are reported. In our patients the fistulae remained asymptomatic and were incidentally detected, so that neither surgical nor medical measures had to be taken. Reviewing the rather scarce literature on this subject the etiology, symptomatology, prevention and therapy of these fistulae are discussed.

Adult↗

The treatment of chronic pyelonephritis with carindacillin.

Forty-two patients with a radiologically confirmed diagnosis of chronic pyelonephritis were treated with 1 g carindacillin every 6 hours over a period of 6 weeks. An underlying urological disease was present in 84% of the 38 patients for whom sufficient data were available for evaluation. The results of carindacillin treatment, as judged by bacteriological evaluation 1 month post-treatment, were good in 12 (32%) and moderate in 9 of the patients. This success rate was remarkable in that all of the patients had been treated previously with one or more other antibiotics and chemotherapeutic agents with little or no response. The authors recommend that, because carindacillin has proved so valuable in treating chronic as well as acute urinary tract infections, its use should be limited to patients with serious disease who have not responded to other treatment.

Adolescent↗

Urological complications after kidney transplantation.

The uroradiological changes and complications with 110 patients who did undergo a total of 119 renal transplantations are discussed under the following 4 topographical headings: perirenal and intrarenal, ureter including the anastomosis, bladder, urethra. In our material we found a lymphocele in 1 patient, papillary necrosis in 3, ureteral obstruction in 6, urinary leakage in 23, reflux in a total of 23, renal calculi in 1 and bladder concrements in 1.

Calcinosis↗

Successful management of postoperative hemorrhage of the kidney by selective transcatheter embolization.

A case is reported where postoperative hemorrhage from the kidney was successfully managed by selective transcatheter embolization of the bleeding vessel. A review of the literature reveals that only three papers have been published dealing with selective embolization for controlling hemorrhage from the kidney. Our case is another illustration of the possibilities and usefulness of this method of treatment in the management of persistent postoperative hemorrhage.

Adolescent↗

Flavoxate hydrochloride in the treatment of detrusor instability.

42 patients with 'unstable bladder' were treated with flavoxate hydrochloride. A previous treatment with parasympathicolytic drugs (propantheline bromide and/or emepronium bromide) was unsuccessful. The instability of the detrusor was proven by a urodynamical investigation. Flavoxate hydrochloride is a papaverine-like smooth muscle relaxant. The results and the complications of the treatment are discussed.

Adolescent↗

Renal transplantation into an ileal conduit.

Since the selection criteria for renal transplantation have become less stringent as a consequence of improved graft survival and decreased mortality, patients with severe structural anomalies of the lower urinary tract can now benefit from renal transplantation into an ileal conduit. This is illustrated by two succesful cases. The opertative procedure is discussed, and the possibilities for the future are mentioned.

Adult↗