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Biomedical subjects

F M Egart

Publications and source records attributed to F M Egart.

At least 37 records · Page 2Linked to original sources

[Aldosterone and progesterone content and blood renin activity in women with idiopathic edema syndrome in various phases of menstrual cycle].

Aldosterone and progesterone content and renin activity were studied by the radioimmunological method in women with the idiopathic edema syndrome and in healthy women in various phases of the menstrual cycle. The most significant differences were revealed in the luteinic phase of the cycle. A parallel elevation of the renin activity and of the aldosterone level against the background of a high progesterone level occurred in healthy women at this phase. Patients showed greater increase in the aldosterone level with the reduction of renin activity and a low progesteron level. Hyperaldosteronism was observed in patients with the idiopathic edema syndrome in all the phases of the cycle. It is suggested that an excessive elevation of the aldosterone level and a decrease in the progesterone level in the luteinic phase of the cycle could served as one of the pathogenetic mechanisms of the edema syndrome formation.

Adult↗

[Various hormonal interrelations in idiopathic edema].

The content of aldosterone and renin activity were examined together with the determination of progesterone, estradiol, gonadotropins and prolactin in the blood of 39 women with idiopathic edemas and in 15 normal women in different phases of menstrual cycle. Women with idiopathic edemas showed a number of hormonal deviations: absolute and relative hyperaldosteronism, particularly demonstrable in the ortho-position, impairment of physiological stability between aldosterone levels in the luteic and folliculin phases; a decrease in progesterone level in the luteic phase; a decrease in the absolute amount of estrogens in the folliculin phase and relative hyperestrogeny in the luteic one; an increase in prolactin content in the early folliculin phase in a considerable number of patients (50%). It is assumed that deviations described might be involved in the formation of edemas.

Adult↗

[Electroencephalogram of patients with the idiopathic edema syndrome].

Patients (45) aged from 19 to 52 years with the syndrome of idiopathic edema were examined by the electroencephalographic method. The great majority of the patients displayed a distinct increase of the theta-activity with some reduction of the alpha-activity. Such shift in the frequency composition could be interpreted as a reflection of the involvement of diencephalic structures into the pathological process. An extreme irregularity of the frequency and the amplitude of the main rhythm was revealed in 14 of 45 patients on the EEG; this, in combination with clinical symptoms, led to a supposition that the regulatory functions of the hypothalamus were disturbed.

Adult↗