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F M Gonzalez

Publications and source records attributed to F M Gonzalez.

29 records · Page 2Linked to original sources
PubMed1976

Effect of sodium acetate infusion on renal function in the dog.

Sodium acetate (AC) is routinely used in dialysis solutions in hemodialysis units as it provides a ready source of fixed base. The renal dynamics of the buffer salt are not well known. Anesthetized dogs received i.v. infusions of AC at a rate of 40 to 600 muEq/kg/min. Urinary AC and bicarbonate excretion was measured and correlated with PAH and creatinine clearance and urinary electrolyte excretion. AC appeared in the urine as quickly as it was detected in the plasma. Its excretion gradually increased and tended to parallel bicarbonate excretion. PAH clearance increased with the advent of AC infusion, plasma pH and bicarbonate increase as AC is introduced. AC infusion caused an immediate drop in blood pressure. The systolic blood pressure returned to control in 3-5 min; there was a more gradual return in diastolic pressure. We conclude that AC is filtered and excreted into the urine at low plasma levels and has a low renal threshold.

Acetates↗
PubMed1968

Renal biopsy.

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Adult↗
PubMedDate not supplied

Cold carbon apparatus for hemodialysis.

A prototype of artificial kidney with regeneration of the dialysis fluid in active carbon at low temperature is presented. The data obtained through a series of simulated dialysis show that carbon adsorbs, besides creatinine and other compounds, urea in satisfactory quantities. Furthermore, the possibility of completely regenerating carbon with tap water washing makes the routine use of an artificial kidney based on a cold operating carbon depurator extremely practical.

Adsorption↗
PubMedDate not supplied

Steroid treatment for routine immunosuppression in cadaver renal transplantation. A survey of hospitals.

A review of data from 22 hospitals in the U.S. and Canada, comprised of information on 1700 kidney transplant patients, shows a consistent pattern with respect to usage of steroids both as routine treatment and for rejection episodes. High doses are associated with greater patient mortality. Graft survival is also adversely affected by very high doses, but only in the immediate post-transplant period. Our data suggest that for optimal graft and patient survival the dosage of steroids should be less than 150 mg/day of methylprednisolone on days 1-3, less than 50 mg/day of prednisone on days 4-21, less than 30 mg/day on days 22-30, and less than 20 mg/day between one mo and one yr.

Cadaver↗