PubMed Health⌕ Search

Biomedical subjects

F M Jüttner

Publications and source records attributed to F M Jüttner.

At least 19 recordsLinked to original sources
PubMed1990

Pitfalls in intraoperative frozen section histology of mediastinal neoplasms.

We evaluated the reliability of intraoperative frozen section histology in 149 mediastinal tumours of which 106 lesions were localized in the anterior, 18 in the central and 25 in the posterior mediastinum. Gross non-resectability was ruled out by preoperative imaging. No preoperative cytological or histological diagnosis was obtained in any case. At thoracotomy, 3 biopsies from 3 different sites of the tumour were processed for frozen section as well as for paraffin histology and immunohistochemistry. In 67 of 73 benign lesions (91%), the intraoperative diagnosis was correct, 5 cases could not be classified by frozen section and 1 case had to be revised. Only 28 of 76 malignant lesions (36.8%) were diagnosed correctly by intraoperative frozen section. In 27 cases (35.5%), no intraoperative classification was possible and in 21 patients (27.6%), the diagnosis was wrong with the consequence of surgical overtreatment for lymphoma misinterpreted as thymic cancer in 3 cases. In patients in whom preoperative investigations suggest borderline resectability, a staged procedure to obtain histology prior to definitive surgery could prevent overtreatment.

Adolescent↗
PubMed1989

[Permeability of the alveolocapillary membrane during unilateral lung lavage. An experimental study].

Experimental unilateral continuous lung lavage in a nonregenerating system containing 3000 ml isotonic crystalloid was performed in 12 pigs to determine the permeability of the alveolocapillary membrane under these conditions. The maximum time of lavage was 270 min. The concentrations of ions in both serum and fluid were determined at defined intervals. Exponential functions adjusted to the electrolyte changes in the fluid suggest different types of kinetics: sodium and urea adapted rapidly to serum concentrations. The half-time of the exponential function was short, the permeability constant high. Calcium, phosphate, and creatinine increased significantly, the permeability constant being lower than for urea. Potassium showed a linear increase, possibly due to influx from intracellular compartments. Total protein and albumin increased only initially, levelling far below the serum values. The low permeability constants of protein and albumin indicate an almost total lack of permeation, the initial increase possibly being due to washout of the epithelial lining fluid compartment. There was only a minimal loss of lavage fluid into the organism.

Animals↗
PubMed1988

[Value of 24-hour long-term pH monitoring with computer-assisted evaluation in gastroesophageal reflux disease].

There are a variety of diagnostic procedures in use to confirm the diagnosis gastroesophageal reflux (reflux-esophagitis, GER). The accuracy of the described methods are different. Computerized 24 hours long term pH monitoring has established to be a very reliable procedure in the diagnosis of GER. From 1984 to 1986 134 patients underwent 24 hours pH monitoring besides X-ray, scintiscan, and esophageal-manometry. The combination of manometry and 24 hours pH monitoring has given the biggest insight into the pathogenesis of GER and seems to be undispensable for specific therapeutic procedures.

Electrodes↗
PubMed1988

Solitary coin lesion in patients with malignant melanoma: an indication for thoracotomy?

In five patients solitary pulmonary lesions were detected radiographically during routine follow up after malignant melanoma. Surgical removal was done in each case under the tentative diagnosis of metastases. Histologically, two lesions turned out as benign chondroma, one as organized pulmonary infarction and one as bronchogenic carcinoma. Only in one patient was a melanoma metastasis present. The findings underline the usefulness also in malignant melanoma of a surgical approach in suspected solitary pulmonary metastases.

Adult↗
PubMed1987

[Misinterpreted expansive process of the middle lobe of the lung caused by unnoticed aspiration of a tooth].

In a patient of 78 years of age a diagnosis of a suspected expansive process of the middle lobe was made on the basis of the clinical findings and a plain radiography of the thorax. Fibre bronchoscopy revealed a subtotal stenosis of the middle lobe bronchus on the right side. The tissue sample revealed a chronically inflamed granulated tissue. Subsequent tomography of the hilus region in two planes showed a foreign body situated in the bronchus intermedius and extending into the middle lobe bronchus. Bronchoscopy was then repeated and an incisor tooth with two mental clamps was removed. A remarkable fact in this case was that the patient was unable to remember the aspiration incident, and it was also remarkable that the shape of the shadow that showed up in the middle lobe segment justified the suspicion of a tumour, although generally atelectasis or pneumonia show up on the x-ray film as sequels of an aspiration if an aspiration has taken place.

Aged↗
PubMed1986

[Perioperative adjuvant chemotherapy with bleomycin in bronchogenic squamous cell cancer. A prospective randomized study].

Bleomycin (BLM) was given perioperatively and 3 and 6 months postoperatively in a dosage of 150 mg per course (total: 450 mg) to 37 patients with surgically resectable squamous-cell lung cancer. 37 randomized control patients with resectable squamous-cell lung cancer were compared to the chemotherapy-group. 5-year overall survival of the BLM group was 46.3%, that of the controls 40.5% (Mantel-Haenszel test; p greater than 0.05). BLM-treated stage I showed a 5-year survival of 47.9% (controls: 55%), BLM stage II 50% (controls: 33.3%), BLM stage III 40% (controls: 21.4%). The difference is not statistically significant. No severe adverse effects of therapy on either wound healing, or perioperative mortality of lung function were observed.

Bleomycin↗
PubMed1986

Pitfalls in the diagnosis of pulmonary metastases in malignant melanoma.

Solitary pulmonary lesions were detected roentgenographically in two melanoma patients during routine follow-up examinations. Melanoma metastases were suspected and the tumors were surgically removed. One turned out to be bronchogenic carcinoma, the other was found to be a chondroma. These cases indicate that in suspected solitary pulmonary melanoma metastases a surgical approach may be reasonable.

Carcinoma, Bronchogenic↗
PubMed1985

[The lower esophageal sphincter after sclerosing of varices].

Fiberendoscopic paravasal sclerotherapy of esophageal varices with Polidocanol at concentration of 1%, is a palliative therapy of a serious sickness. Due to the location of esophageal varices, paravasal sclerotherapy with all its alteration of the esophageal wall takes place in the lower third with its lower sphincter. Twenty middle-aged patients, both sex, with esophageal varices (stadium II-IV due to Paquet) underwent clinical, endoscopic and esophagomanometric control after completion of sclerotherapy. By reaching the therapeutic goal--the subepithelial layers--no pathologic change of the motility of the esophagus has been seen.

Adult↗
PubMed1984

Reconstructive surgery for tracheobronchial injuries including complete disruption of the right main bronchus.

Important features of diagnostic and operative management and the postoperative course of tracheobronchial injuries as well as pathological findings at the anastomosis are discussed in a review of our 11 cases from the last 12 years. Diagnosis was established clinically, localization of the rupture was carried out by rigid or fiberoptic bronchoscopy. Tracheobronchial continuity was reestablished by end-to-end anastomosis of the ruptured bronchi, by direct suture of any tracheobronchial tears, or by patching inveterated lesions. Two cases of rupture of the right main bronchus are presented separately, considering clinical, diagnostic, operative and histopathologic criteria.

Adolescent↗
PubMed1984

[Alternative sclerosing technic for the wall of the esophagus in esophageal varices. Experiences with 103 cases of sclerotherapy].

Haemorrhage caused by oesophageal varices, will produce the highest complication rate of portal hypertension. Fiberendoscopic sclerotherapy has been widely introduced for treating those oesophageal varices. Two methods which are technically different are applied: intravariceal injection of the sclerosing solution and paravariceal injection inducing subepithelial fibrosis of the oesophageal wall. Twenty-five patients with oesophageal varices were subjected to 103 fiberendoscopic sclerotherapy sessions. Before every session a Sengstaken-Blakemore tube was inserted in the oesophagus. Sclerotherapy took place along this tube. This modified technique of paravariceal sclerotherapy of the oesophageal wall provides the possibility of secure sclerotherapy by using no specially adapted fiberoptic endoscopes.

Adult↗