Biomedical subjects

F M Johnsen

Publications and source records attributed to F M Johnsen.

5 recordsLinked to original sources

PubMed1996

[Caroli's disease].

Caroli's disease (CS) is a rare malformation of the bile duct with multiple segmental communicating dilatations of intrahepatic bile ducts affecting the whole of or parts of the liver. The disease is presumably of autosomal recessive hereditary character. Caroli described two types: the rare isolated variety (type 1), is characterized by recurring episodes of cholangitis. The more frequently occurring type 2 is associated with congenital hepatic fibrosis, and consequently there are also symptoms of portal hypertension. Both types may make their first appearance at a very early age. A case story is presented. In the light of the development of carcinoma in 7% of the patients, the authors recommend that patients who cannot be operated radically should have regular, clinical follow-ups including ultrasonography and biopsies if necessary.

Adult↗

PubMed1996

[Ultrasonically guided gastroscopically assisted percutaneous internal drainage of pancreatic pseudocysts].

Non-surgical procedures are increasingly being used for drainage of pancreatic pseudocysts. We describe the results of placement of a double pigtail cystogastric stent under ultrasonographic and gastroscopic guidance. The stent was placed in 22 of 25 pseudocysts. There was no mortality associated with the procedure and the total complication rate was 20%. The cysts resolved in all patients and 87% reported reduction of abdominal pain. The median stent-time was 347 days and there were no cyst recurrences or complications during that time. After removal of the stent four out of 19 patients had recurrences. After placement of a second stent in these four patients there were no recurrences. Treatment with a cystogastric stent is comparable to surgical cystogastrostomy as regards to results and has fewer complications.

Adult↗

PubMed1993

[Intrathoracic perforation of stomach ulcer in a massive hiatal hernia].

A case of intrathoracic perforation of a chronic gastric ulcer in a hiatus hernia is presented. A 67-year-old woman had suffered from interscapular pain and epigastric discomfort following large meals for four years. During the week before admission, the epigastric and interscapular pain increased, reaching a crescendo in the 24 hours before the patient's arrival in the emergency room. Chest and abdominal x-ray showed free gas and a large hiatus hernia with an intrathoracic stomach. At laparotomy, the stomach was gently returned to the abdominal cavity, and a perforated chronic gastric ulcer was found on the greater curvature. The ulcer was excised, and the diaphragmatic crura were approximated. Apart from wound dehiscence, the postoperative course was uneventful.

Aged↗

PubMed1992

[99mTc-HMPAO leukocyte scintigraphy in inflammatory intestinal disease].

Eighteen patients, suspected of active inflammatory bowel disease, were investigated. The 99mTc-HMPAO-leucocyte scintigraphy was evaluated using the results of the simultaneous clinical examinations, which included clinical and biochemical parameters, small intestinal series, colonoscopy and, in two patients, operation, as reference. In agreement with the clinical examinations, the leucocyte scintigraphy indicated active inflammatory bowel disease in 14 of the 18 patients. The leucocyte scintigraphy disclosed inflammation in all of the 19 bowel segments, in which the clinical examinations indicated active inflammation. In three patients with Crohn's disease the scintigraphy indicated more extensive inflammation. A correlation between the scintigraphic activity and the Crohn's Disease Activity Index was found. However, the leucocyte scintigraphy did not seem useful as a disease activity index. The 99mTc-HMPAO-leucocyte scintigraphy seemed especially useful in severely ill patients and in patients suspected of relapse.

Adolescent↗

PubMed1991

[Diagnosis of popliteal cysts and their complications].

Popliteal cysts and their complications (rupture, expansion and pseudothrombosis) all of which may simulate deep venous thrombosis of the lower extremity may be diagnosed reliably by ultrasonography. Even small cysts can be detected, their extension can be defined and rupture with leakage of fluid into the surrounding muscles can be diagnosed. Phlebography can be avoided in most cases. Arthrography rarely gives additional information. Ultrasonography of the erect patient is recommended if rupture is suspected.

Adult↗