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Biomedical subjects

F M Matschinsky

Publications and source records attributed to F M Matschinsky.

At least 181 records · Page 10Linked to original sources

Kinetics of insulin release from the perfused rat pancreas caused by glucose, glucosamine, and galactose.

Under appropriate conditions, not only glucose but also glucosamine and galactose can serve as potent stimulants for insulin release from the isolated, perfused rat pancreas. Since galactose and, probably, glucosamine are not metabolized in the islets, and since these three compounds have in all likelihood common sites of action, it is postulated that a glucoreceptor of broad specificity is involved in the mechanism of insulin release, and that metabolism of glucose is not an essential part of the releasing action of this sugar.

Adenylyl Cyclases↗

Prostaglandins: enzymatic analysis.

By, means of al specific nicotinamide-adeninie dinucleotide-dependent prostaglanidin dehydrogenase from swine lung, an enizymatic method has been developed for the assay of prostaglandins. The method permits analysis with a lower limit of 10(-12) mole of prostaglandin.

Animals↗