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Biomedical subjects

F M Randall

Publications and source records attributed to F M Randall.

4 recordsLinked to original sources

Ethical issues in palliative care.

The relief of suffering is one of the aims of health care. Pain relief is a moral obligation in health care, not an optional extra. Doctors have moral obligations to strive to relieve pain, to be competent in basic pain control, and to endeavour to give patients an adequate understanding of their illness and painkillers. The most common moral problem in pain control in terminally ill patients is the conflict between the obligation to relieve suffering and the obligation to prolong life. The law prohibits intentionally causing the death of another person. Debates follow as to what constitutes an intention to cause death, and what actually constitutes a cause of death. At present, doctors are legally permitted to give sedatives and analgesics to terminally ill patients with the intention of relieving suffering, even if life is shortened. The moral principle of the 'double effect' relates to this and is explained. It relies on a distinction between intended and foreseen effects of treatment. Some people dispute the distinction between intended and foreseen effects and claim that the principle of double effect allows doctors who intend euthanasia to carry it out under cover of the law. This debate is explored in the article. Finally, is it ever morally justifiable to end the patient's life on the grounds that this is the only way to end pain? Even if it is, should euthanasia be legalised? A brief comment on these issues, and the roles of law and morality, are made.

Ethics, Medical↗

The use of instant moiré photographs to reduce exposure from scoliosis radiographs.

A total of 258 patients with some degree of idiopathic scoliosis was monitored with both radiographs and moiré photography to determine the degree of progression of spinal curvature. The use of polaroid photography to document moiré fringe patterns proved to be a rapid and useful process for placing an instant photographic record in patient charts while conducting routine physical examinations. Standardization of procedures for making and evaluating moiré photographs reduced patient exposure to X-rays.

Adolescent↗

Midazolam and diazepam: maternal and fetal effects in the pregnant ewe.

Maternal and fetal hemodynamic effects and placental transfer of midazolam (RO 21-3981, Hoffman-LaRoche) and diazepam were studied in chronically instrumented pregnant ewes. Diazepam administration resulted in greater increases of maternal and fetal heart rates and maternal blood pressure, and greater alteration of total uterine blood flow than did administration of comparable doses of midazolam. Neither drug altered fetal mean arterial pressure or maternal and fetal respiratory gases. Although the absolute blood concentrations were higher, the fetal:maternal drug concentration ratios were consistently less for midazolam than for diazepam, suggesting less placental permeability of midazolam.

Animals↗