Biomedical subjects
Publications and source records attributed to F M Watson.
There is a group of painful inflammatory conditions that involve the soft tissues of the hand, wrist, and forearm. These generally occur without underlying systemic diseases, and the pain frequently results from tendon or nerve compression. Recognition of these difficulties can lead to appropriate treatment, often nonoperative, resulting in symptomatic cure. Occasionally, surgical treatment is required.
Fractures in the hand, as elsewhere, usually fall into identifiable patterns. With prompt diagnosis and appropriate management, most fractures can be treated satisfactorily by closed means. However, a small percentage of fractures in the hand do require treatment by open means. Early recognition and early treatment of these injuries will usually avoid significant complications.
A case of simultaneous dislocation of both interphalangeal joints in a single finger in a volleyball player is reported. Reduction was achieved with longitudinal traction and full motion was regained following appropriate immobilization. It appears that the mechanism of injury was a hyperextension force which initially produced dorsal dislocation of the distal interphalangeal joint but even after producing this injury was still prominent enough to produce dorsal dislocation of the proximal interphalangeal joint.
Acute calcareous deposits of the hand and wrist have been infrequently reported. A review of the literature and five recent cases indicate that these painful lesions will respond rapidly to immobilization and medication. Differentiation from infection is important.
Five years after an untreated ulnar fracture, a young man seen with no active or passive forearm rotation was found to have a radio-ulnar synostosis, which was surgically excised with interposition of a silicone membrane and soft tissue to decrease any tendency for new formation of the synostosis.
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Five cases of acute hematogenous osteomyelitis occurring at the site of closed fractures are reported. This is a serious and potentially lethal complication resulting in directly in the death of 3 of the 5 patients. This is an unusual occurrence seen infrequently, and subsequent delay in diagnosis is frequent. An awareness of this complication (which usually occurs in the face of decreased resistance to infection) coupled with careful inspection of the fracture site, evaluation of the patient as a whole, and a high index of suspicion will allow earlier diagnosis and possibly more successful early treatment. Because of the pathophysiology of this lesion and the usual delay in diagnosis, initial treatment should include wide surgical drainage of the abscess with proper debridement and bony resection. This may involve procedures which at first glance may appear to be mutilating. In these patients with decreased resistance to infection, the initial appropriate choice of antibiotics is essential.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
If the newborn of a socially organized CBA/USC mouse colony are regularly removed (force breeding), the social order breaks dowm. There is fighting among the males and the young are lost due to neglect and injury by the females (cronism). A high incidence of mammary tumor formation is observed during the disorder of such formerly socialized groups. In the pilot study being reported, force breeding initiated at the sixth month of colony life eventually at the ninth month led to fighting and the loss of young by cronism. All 12 female colony members developed tumors during the subsequent 5 months. Meanwhile, tumors developed in only 8% of the same age Study Siblings and in 46% of Study Breeders maintained under rapid breeding conditions. Force breeding is a knowm moderately effective tumorigenic technique. Since tumors did not occur in the population cage until its social system broke down, this suggests that the combination of force breeding and social disorder-induced neuroendocrine changes is peculiarly favorable to tumor development.