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Biomedical subjects

F Möller

Publications and source records attributed to F Möller.

At least 37 records · Page 2Linked to original sources
PubMed1995

Inverse control of growth hormone and prolactin secretion in clonidine-stimulated dairy cattle.

Clonidine is a specific alpha-2-adrenoreceptor agonist that stimulates growth hormone (GH) release in animals and humans. This drug was used to study the GH and prolactin (PRL) secretory response in dairy cows and heifers. An i.v. infusion of 10 micrograms/kg body weight induced GH release to a peak concentration after 30-60 min, while 2 micrograms/kg had no effect on GH secretory patterns. Plasma PRL decreased significantly (P < 0.01) starting 15-60 min after both doses of clonidine, this effect lasting up to 6 h. Clonidine significantly lowered plasma insulin (P < 0.01) and raised plasma glucose (P < 0.01). The changes in plasma GH, PRL, insulin and glucose differed significantly between doses, the 10 micrograms/kg dose being more effective (P < 0.01). The results of our investigation in dairy cattle provide evidence of (i) an increase in GH release after 10 micrograms/kg clonidine; (ii) a concomitant decrease in PRL secretion, hence GH and PRL secretion in cattle appear inversely controlled; (iii) a significant difference between the effects of the 2 and 10 micrograms/kg doses and (iv) no relationship between the changes in plasma GH and PRL after clonidine and plasma hormone levels before treatment.

Animals↗
PubMed1990

Diagnosis of bone and joint infection by leucocyte scintigraphy. A comparative study with 99mTc-HMPAO-labelled leucocytes, 99mTc-labelled antigranulocyte antibodies and 99mTc-labelled nanocolloid.

Fifty-five patients with 60 suspected infections of bones or joints were studied with 99mTc-hexamethylpropyleneaminooxine- (HMPAO-) labelled leucocytes and 99mTc-labelled antigranulocyte antibodies, in part supplemented with 99mTc-labelled nanocolloid. The findings using the different procedures were in good agreement. Apart from in vertebral lesions, a negative scan--even if the radionuclide bone scan is positive--excludes an infection with high probability (sensitivity 94%). The low specificity (57%) is due to positive imaging of various non-infected lesions. Spondylitis usually shows as non-specific cold lesions. A subtraction technique with computer assisted analysis of HMPAO and nanocolloid scans provides a more precise diagnosis of this condition.

Adolescent↗
PubMed1983

[Stimulation of the natural self-purification of soil].

Connected with the elaboration of the sanitary norm of cadmium in soil were performed examinations to appoint the self-purification index. This index is the highest permissible concentration of a noxious chemical substance in soil not yet injuring irreversible the process of natural self-purification. As criterions of the self-purification were selected normal and potential respiration, quantity of bacteria, actinomyceta, fungi, proteolytic, nitrifying, and cellulolytic micro-organisms, inhibition of Bacillus subtilis and Phormidium autumnale, survival and increasing ability of Escherichia coli, Streptococcus faecalis and Salmonella give. Among the influence of various concentrations of cadmium was find out the self-purification index of 500 mg Cd++/kg. By experience are offered methodical improvements at the elaboration of self-purification indices.

Bacteria↗
PubMed1979

[Soil-hygienic points of view with respect to intensive plant production in socialistic agriculture (author's transl)].

With intensified plant production, also soil-hygienic points of view must be taken into account. Measures like fertilization, irrigation, and amelioration must be carried through in such a way that any damage to human health is excluded. As factors of risk have to be regarded pathogenous micro-organisms and parasites from sewage, sludge, and liquid manure, nitrate, potassium, pesticide residues, and heavy metals from agrochemicals and manure, as well as antibiotics from therapeutic and prophylactic treatments. The necessity of precise legal regulations emphasized.

Agriculture↗