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Biomedical subjects

F Maehara

Publications and source records attributed to F Maehara.

29 records · Page 2Linked to original sources

[Ganglioglioma in a child--report of a case].

A seven-year-old boy who was admitted for surgical treatment for intractable epilepsy was found to have a ganglioglioma in his left parietal lobe. Since four years old, he had been suffering from the seizure and treated with various anticonvulsants without satisfactory effects. As its frequency increased, the dose had to be increased. Thus, it was sought for the possible surgical approach. On the CT scans, an egg size low density zone without contrast enhancement was observed in the subcortical region of his parietal lobe. There was marked thinning on inner table of the skull immediately above the zone. He was operated under fronto-temporo-parietal craniotomy. When the dura matter was opened, pale cerebral cortex protruded. Complete removal of the tumor was not possible, since there was not clear boundary between the mass and normal tissue. Based on histological study, it was diagnosed as ganglioglioma, because its main body contained increased number of glia which had deeply stained ununiform size nuclei. After the operation, he showed neither motor paralysis nor sensory disturbance and was able to sustain his activity with less amount of anticonvulsant.

Brain Neoplasms↗

[Two adult cases of moyamoya disease with intraventricular hemorrhage--angiographic evaluation of periventricular vascular anatomy].

In order to show the vascular anatomy in periventricular region, two adult cases of moyamoya disease with intracerebral hemorrhage extending into lateral ventricle were presented. And we discussed the relation between the vascular anatomy and the form of hemorrhage in moyamoya disease. The first case was a 46-year-old woman admitted for nausea and vomiting following headache for four days. CT scan revealed a high density area in the upper portion of body of right lateral ventricle showing intracerebral hemorrhage which extended into the lateral ventricle. On angiogram, typical moyamoya disease was noted. The ventriculofugal arteries from the posterior lateral choroidal artery was detected which indicated developed ventriculofugal perfusion. The second case was a 52-year-old man who was hospitalized sudden onset of headache, vomiting and consciousness disturbance. CT scan revealed a high density area suggesting of hemorrhage in the head of right caudate nucleus. It perforated into the right anterior horn of lateral ventricle with spreading over the other ventricles. We observed similar findings on the angiograms to the first case. In this case, however, the lateral striate arteries were involved instead of the posterior lateral choroidal artery. It should be pointed out that, in both cases, the area of hemorrhage in CT scan coincided with the area of developed ventriculofugal perfusion in angiograms.

Arterial Occlusive Diseases↗

[Localized cerebral tumor mass in systemic non-Hodgkin's lymphoma--report of two cases and review of the literature].

The pathophysiology of cerebral tumor mass in cases of systemic non-Hodgkin's lymphoma is not well known. We experienced with two cases with this lesion. The purpose of this report is not only case presentation but also an analysis of cases from the literature from the clinical, radiological, histological, immunological and therapeutic aspects. Case 1 was a 82-year-old man who had weakness in the right arm and for the past month. For about two years he had been received anticancer chemotherapy because of a systemic malignant lymphoma at another hospital. Neurological examination revealed disorientation and right hemiparesis. Microscopic and immunological studies of the biopsy specimen of the enlarged supraclavicular node showed a non-Hodgkin's B-cell lymphoma of the diffuse large cell type according to the Lymphoma Study Group (LSG) classification. The clinical stage (CS) of the lymphoma was IV except for the CNS lesion by systemic examination including lymphography. CT scan on admission revealed remarkable enhancement of a nodular high density area near the lateral ventricle, accompanied by surrounding low density. Angiography failed to reveal a tumor stain. CSF cytology was positive although no pleocytosis was observed. Case 2 was a 70-year-old man who had weakness of the right foot for two weeks. About three years ago he underwent orchiectomy for a testicular tumor at another hospital. Neurological examination revealed disorientation, memory loss and right hemiparesis.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

[Diagnosis of the chiasmal meningioma (author's transl)].

Not infrequently, it is difficult to differentiate the chiasmal meningioma from other suprasellar tumors, especially pituitary adenoma and craniopharyngioma. Authors examined 7 cases of chiasmal meningioma from neurological, endocrinological and neuroradiological points of view in comparison with the cases of pituitary adenoma and craniopharyngioma. As the results, the following features can be regarded as the differential characteristics of the chiasmal meningioma. 1) It was predominated in female of over 40 years of age. 2) Duration of the symptoms before admission was usually 2--3 years. 3) Disturbance of visual acuity and defect of visual field were initially unilateral in most of the cases, then extended to the other side when the disturbance of one eye had become severe. Visual field defect tended to be of irregular bitemporal hemianopsia with frequent involvement of peripheral nasal field. 4) Evidence of the endocrine disturbance were very scanty until the end stage. 5) Postero-superior elevation of A1 portion of the anterior cerebral artery in the tuberculum sellae meningioma was one of the pathognomonic features. 6) In the case of meningioma extending from tuberculum sellae to dorsum sellae or originated from dorsum sellae, PEG showed a finding of "capping on the dorsum sellae" and the tumor shadow over the posterior clinoid process took different feature from pituitary adenoma or craniopharyngioma.

Adenoma↗

Brain anomalies found in 18 trisomy: CT scanning, morphologic and morphometric study.

Brain anomalies in 9 cases of cytogenetically proven 18 trisomy were reported. In addition to the various cerebral anomalies such as gyral or lobar abnormalities, hippocampal dysplasia, abnormal lateral geniculate body, agenesis or hypoplasia of the corpus callosum, absent or hypoplastic olfactory nerves, small optic tracts, and dysplasia of the inferior olivary nucleus, hypoplasia of the cerebellum and ventral pons was found in all cases. Cranial computed tomography was performed and revealed cerebellar and pontine hypoplasia with or without hypoplasia of the posterior cranial fossa as a characteristic finding in all 9 cases. A comparative morphometric study was done using age-matched controls. Macroscopically, the weight ratio of the cerebellum and brain stem to the whole brain was reduced compared with the controls. Microscopically, the thickness of the internal granular layer of the cerebellum was reduced especially at the convex area.

Brain↗