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Biomedical subjects

F Marcheş

Publications and source records attributed to F Marcheş.

6 recordsLinked to original sources
PubMedDate not supplied

[Early anti-HPV 16 protein antibodies in patients with anogenital tumors].

A study was worked out in female patients with anogenital tumors and in apparently healthy women, aimed at the detection of antibodies against E4 and E7 HPV 16 proteins. As regards the detection of HPV 16 infection, the DNA hybridization and Western-blot results were in good agreement. The HPV 16 infection was detected in a relatively high number of the patients (17 out of 24) and of the apparently healthy women using Western blot.

Adult↗
PubMedDate not supplied

Estimation of avidin activity by two methods.

The biological activity of avidin was estimated by two different methods. The spectrophotometric method used the avidin titration with biotin in the presence of 4 hydroxiazobenzen-2'carboxilic acid as indicator. In the radioisotopic determination the titration with tritiated biotin was accomplished. Both methods led to the same results, but the spectrophotometric one is less avidin expensive and more rapid, being more convenient.

Animals↗
PubMedDate not supplied

[The avidin-biotin system. Its application in virology].

The report briefly reviews the strategies of utilisation of the avidin-biotin system and its variants, as well as the applications of this system in different fields, especially those linked to the diagnosis and the treatment of some viral and bacterial infections. Some of the techniques using the system are presented, as well as its advantages and the perspectives to ameliorate the methodologies and to enlarge the field of its applications.

Antibodies, Monoclonal↗
PubMedDate not supplied

[The potentials for immunization against influenza using liposome-incorporated viral surface antigens].

Studies were conducted using uni- and multilamellar liposomes to establish optimum conditions for influenza antigen incorporation in view of their transport to the target cells for experimental influenza prophylaxis in hybrid white mice. Radiometric determinations showed a good level of preparation purification, a good efficiency of incorporation in liposomes of the active biological material, the liposome linked radioactivity distribution among different organs. Charged liposomes induced solid and long lasting resistance against influenza control infection.

Animals↗