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F Martínez Navarro

Publications and source records attributed to F Martínez Navarro.

13 recordsLinked to original sources
PubMed2005

An outbreak of Campylobacter jejuni enteritis in a school of Madrid, Spain.

An outbreak of gastroenteritis caused by Campylobacter infection was identified in May 2003 in a school in Madrid, Spain. Eighty one cases were identified in a total of 253 people studied. A retrospective cohort study showed that a custard made with ultra high temperature (UHT) milk was associated with illness (RR: 3.15; 95% CI: 1.25-7.93). The custard was probably contaminated with Campylobacter jejuni from a raw chicken prepared a day previously in the same kitchen. Our recommendations were to periodically remind the school s authorities how to act if an outbreak should be suspected, to include the monitoring of a food handler s working day in each environmental investigation in order to detect any risk behaviour; to implement microbiological analysis from the surfaces and utensils of the collective kitchens and improve the sanitary education of food handlers.

Adult↗
PubMed2005

Late detection of a shigellosis outbreak in a school in Madrid.

Even though shigellosis in Spain is rare, an indigenous outbreak is occasionally detected. We describe an outbreak in a school in Madrid caused by person-to-person transmission of Shigella sonnei. After the detection of Shigella sonnei in a stool sample from a 3 year old girl, an investigation at her school was initiated. Questionnaires were distributed to the parents of 520 pupils attending the school. A case was defined as a school case if it was the first case in a child's household, and as a household case if other members of the household had fallen ill first. We identified 88 cases (60 pupils and 28 of their family members). The attack rate (AR) was 12% in the school and 32% in the families. There was a significant association between higher AR and lower age. The outbreak lasted for two months. The length and the shape of the epidemic curve of the 60 cases in pupils suggests person-to-person transmission. Shigella sonnei isolated from 5 different cases were typed by pulsed field gel electrophoresis (PFGE) and was found to be an identical strain. The prolonged duration of the outbreak was probably due to delayed detection, and stopped as soon as control measures were introduced.

Child↗
PubMed2001

Incidence of pulmonary tuberculosis and HIV coinfection in the province of Seville, Spain, 1998.

Using the National Notifiable Disease Surveillance System (NNDSS) and Minimum Basic Data Set (MBDS) for hospital discharges we evaluated pulmonary tuberculosis (PTB) surveillance and estimated real PTB incidence and human immunodeficiency virus (HIV) coinfection in Seville in 1998. In addition, we assessed the sensitivity and the positive predictive value (PPV) of the surveillance system. Real incidence of pulmonary tuberculosis was estimated by the capture-recapture method. In 1998, the province of Seville reported 225 cases of pulmonary tuberculosis to the NNDSS, an incidence of 13.2 per 100,000 population. Of the 225 cases reported, 18.2% presented with HIV coinfection, while a total of 194 had confirmed diagnoses. The MBDS accounted for 106 new cases. Of these, 24.8% presented with HIV coinfection and were 58% less likely to be reported to the NNDSS (25-76%, p = 0.001). Applying the capture-recapture method, 426 cases were estimated, an overall incidence of 25.6 per 100,000 population (21.5-28.8). Completeness for each source was similar (47%), and for both jointly was 72.7%. The NNDSS had a sensitivity of 65.3% and a PPV of 89.3%. In conclusion, the NNDSS underestimates PTB and PTB-HIV coinfection in Seville. The high incidence observed in young adults suggests a high degree of tuberculosis endemicity. Hospital records provide a readily accessible, low-cost means of estimating disease incidence.

AIDS-Related Opportunistic Infections↗
PubMed1995

[Public health during Franco's regime].

We compare the most relevant characteristics of the evolution of public health as a science during Franco's regime with the behavior of significant parameters in the evolution of health care in Spain (mortality and morbidity rates, spending on health care, institutional development of the health care system). Our purpose was to characterize how the legacy inherited by current health care legislation in Spain has given rise to the problems currently faced. The backslide during the post-Civil War periiod as a result of the victors' identification of the advances achieved in the Second Republic with leftist policies, delayed modernization imposed by the accelerated process of industrialization, and obstacles caused by the consolidation of National Health Insurance, led to a paradigm based exclusively on medical care.

History, 20th Century↗
PubMedDate not supplied

[Levels of bactericidal antibodies against meningococcus C after vaccination in 2- to 6-year-old children in Andalusia].

BACKGROUND: In 1997, 18.5% of the cases of Meningococcal Disease caused b serogroup C in Andalusia were children between 2 and 4 years of age; ages where the initial immune response and the duration of the capsular A + C meningococcal polysaccharide vaccine is less than in older age groups. Research was designed in order to measure the immune response produced by this vaccine in children from 2 to 6 years of age and to compare it with the natural immunity present in unvaccinated children. METHODS: I. Dual monitoring study: a) groups of children vaccinated previously and control groups, b) groups of children who were going to be vaccinated, for pre and post-vaccination (1, 6 and 12 months) analysis and a control group. II. The bactericidal activity was measured according to the standardised protocol of the CDC with regard to the strain of N. meningitidis C-11. The sera with bactericidal activity (TAB) > 1:8 were considered to be protective. RESULTS: 1 and 2 months following vaccination, the proportion of TAB > 1:8 was significantly higher than that of the control group (65.6% and 73% in comparison to 2.2% and 12%). In the pre-vaccine and post-vaccine (after 6, 7, 12 and 13 months) verification, no significant difference between vaccinated individuals and controls was observed. CONCLUSIONS: The differences between vaccinated and unvaccinated individuals 1 and 2 months following vaccination indicate seroconversion in the vaccinated individuals. For the age group of between 2 to 6 years of age, the bactericidal activity acquired decline quickly, as, after 6 months, differences between this group and the control group are no longer observed.

Antibodies, Bacterial↗
PubMedDate not supplied

[Outbreak of gastroenteritis at a home for the aged in Albacete].

BACKGROUND: We describe the investigation of an acute gastroenteritis outbreak with an explosive beginning, probably waterborne, that occurred in an nursing home in Albacete, in November 1999 and affected 104 inmates and 35 employees. The dominant symptoms were diarrhea and vomiting. METHODS: A case-control study was designed. We carried out a descriptive analysis of facts and crossing of variables with the help of simple tables. A multivariant analysis, by models of logistic regression, was conducted both for the explosive phase and for that of transmission person-to-person. RESULTS: The attack rate for inmates was 45.8% and for employees, 33.7%. An association was found between the use of the main dining-room of the nursing home and the explosive beginning of the outbreak and between the previous presence of a case-patient in the shared bedrooms and the person-to-person transmission. Norwalk-like virus was isolated from faeces samples of four cases. CONCLUSIONS: The analysis of the clinical and epidemiological findings as well as the laboratory results proved the implication of a Norwalk-like virus in this outbreak.

Aged↗
PubMedDate not supplied

[Brucellosis as occupational disease: study of an outbreak of air-born transmission at a slaughter house].

BACKGROUND: The onset of a large number of cases of brucellosis among employees at a slaughterhouse in Zaragoza where sheep from livestock culling procedures were being slaughtered, led to an investigation being made for the purpose of shedding light on the cause of this outbreak. METHODS: This study was organized into three parts: 1) Description of the outbreak 2) Study of the slaughterhouse layout and activity as regards the number of animals slaughtered, the employee workload and the degree of risk involved in each working area and 3) Unmatched case-control study. RESULTS: No significant differences were found among the attack rates by the sections of the slaughterhouse where the employees in question worked. The slaughtering analysis revealed a concomitant fluctuation between the slaughter of culled sheep and the epidemic. The case-control study revealed no significant differences for the risk factors involving working in a risk area, the use of protective measures and cuts/wounds. CONCLUSIONS: This outbreak is related to the slaughter of culled sheep. The fact that no significant difference were found by sections or due to working in a risk area is compatible with an overall explanation. Nor were any differences among the employees found to exist with regard to cuts/wounds or the use of protective measures, which focuses importance on airborne spread.

Abattoirs↗
PubMedDate not supplied

[The evaluation of epidemiological services related to brucellosis in the Autonomous Community of the Basque Country].

BACKGROUND: Spain's Epidemiologic Notifiable Disease Surveillance System (ENDSS) was evaluated by reference to Brucellosis, the zoonoses with greatest incidence countrywide and a disease that is notifiable on a case by case basis in the Basque Autonomous Region (BAR). METHODS: ENDSS information and the use to which it was put, were analysed. Active case searching was carried out via the Microbiologic Information System (MIS), public hospitals and the Occupational Disease Registry (ODR). A comparison was run between reported and search data. The capture-recapture method was used to compare ENDSS against hospital cases. RESULTS: Risks and outbreaks wee detected. Suspect cases were not reported. There was a 40% post-search increase in cases, i.e., 40 versus a previous figure of 24. Sensitivity was estimated at 60%. Predictive Value Positive could not be computed however. No case definition was in force. As estimated by the capture-recapture method, overall sensitivity for both ENDSS and hospital-based surveillance was 84% (95% IC: 70-100). The number of cases estimated by this method was 38 +/- 8. CONCLUSIONS: Underreporting is in evidence and, as a consequence, sensitivity is low. A case definition is called for. Response time is slowed by awaiting confirmation before reporting. The number of cases detected through active searching is compatible with that calculated by the capture-recapture method using only two sources.

Brucellosis↗