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Biomedical subjects

F McKiernan

Publications and source records attributed to F McKiernan.

4 recordsLinked to original sources

First observation of herpes-like virus particles in northern pike, Esox lucius L., associated with bluespot-like disease in Ireland.

Circular whitish granular lesions, 5-12 mm in diameter, were observed on the skin and fins of a wild northern pike, Esox lucius, caught in a lake in the Republic of Ireland. Histological examination of the lesions revealed hypertrophied cells in the epidermis with deeply basophilic enlarged nuclei and dark-staining granular material in the cytoplasm. Transmission electron microscopy of these cells revealed naked hexagonal herpes-like virus nucleocapsids (97 +/- 7 nm) in their nuclei while the cytoplasm contained multiple aggregates of enveloped viral particles. This is the first report of herpes-like virus particles in northern pike originating outside North America, where esocid herpesvirus-1 (EsHV-1) has previously been reported. Shared clinical, histological, morphological and epidemiological findings suggest that the observed particles in this report may also be EsHV-1.

Animals↗

Psychological profiles and motives of adults seeking orthodontic treatment.

Personality profiles and the motivations for seeking orthodontic treatment were investigated in a sample of adult patients. An improvement in dental esthetics was found to be the prime motivating factor, and the decision to seek treatment was usually made by the adult patients themselves. Questionnaires to assess personality traits revealed an atypical group of patients demonstrating neurotic traits. These patients were found to have a significantly different perception of their malocclusion than did the "normal" group of adult patients. Patients with neurotic traits may pose problems for clinicians with regard to expectations both during and at the end of treatment.

Adolescent↗

Computer generation of high-energy x-ray dose distributions.

A computer program for the generation of high-energy x-ray dose distributions has been developed. The program takes account of the fact that the x-ray beam profile, as affected by penumbra, wedges, beam blocks, or flattening filters, is one of the prime determinants of the dose distribution. Doses from primary and scattered radiation are calculated separately by using published tissue-air ratio (TAR) and scatter-air ratio (SAR) data. The dose from scattered radiation is determined by dividing the x-ray field into a series of scattered strips and summing the contribution from each. Wedges or beam blocks are taken into account simply by earning their actual coordinates and linear attenuation coefficients. The program may be used to design wedges, beam blocks, or flattening filters prior to fabrication. Complete libraries of dose distribution for 60Co, 2-, 4-, and 6-MV x rays have been generated.

Computers↗