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Biomedical subjects

F Melon

Publications and source records attributed to F Melon.

8 recordsLinked to original sources
PubMed2000

Digital necrosis in a woman over eighty.

Chronic vascular disorders of the upper limbs are not frequently encountered in women; in addition, advanced age of onset tends to suggest the presence of common diseases such as arteriosclerosis or microembolization. Nonetheless, diagnosis is not always straightforward and in some cases both-laboratory and instrumental findings can do no more than arouse a diagnostic suspicion. We present a case of acro-localized disorder, which proved difficult to diagnose and which we believe may be attributed to a slowly progressing form of scleroderma of the extremities which, in our case, determined positivity of anticentromere autoantibodies.

Aged↗
PubMed1998

[Vascular manifestations in systemic sclerosis (scleroderma)].

Progressive systemic sclerosis (PSS), a disease still of unknown origin, is a generalized autoimmune disorder characterized by immunological abnormalities, microvascular dysfunction, and tissue fibrosis. The mechanism leading to selective microvascular injury in PSS is not completely known, however it is now clear that neuropeptides, vascular endothelium, and disturbances in the regulation of fibroblast function are the three major contributors to the increased fibrosis of skin and internal organs. Thus, endothelial cell and fibroblast dysfunction may be linked through the paracrine activity of soluble endothelial cell products: the cytokine cascade (IL-1, TGF-beta-1, PDGF, TNF, etc.). In systemic sclerosis, the exaggerated generalized vasospastic tendency is clinically represented by Raynaud's phenomenon as shown by an early digital arterial closure after cold stimulation, and by an inadequate vasodilatory response to heat. In this review we summarize recently established data that center around the role of adhesion molecules, immune reactions, and aberrant fibroblast biology and metabolism in effecting vascular and connective tissue alterations in this disease. Only a better knowledge of the pathophysiological process involved in scleroderma might lead to the development of new therapeutic approaches.

Adult↗
PubMed1996

Asymmetries of facial motility during the dissimulation of emotion.

The asymmetrics of facial expression were estimated in a sample of 14 experimental subjects with the Facial Action Coding System during voluntary control of facial mimicry while viewing videotapes. The subjects were instructed to express facially the emotion experienced or to dissimulate their true emotion with a facial expression opposite (incongruous) to what they actually felt. Only during dissimulation did facial mimicry show an asymmetric distribution toward the lower left side of the face.

Adult↗
PubMed1992

[Benign fibrous histiocytoma of the female urethra].

Presentation of one case of benign fibrous histiocytoma of the female urethra in a 49-year old woman. Investigation of the various clinical and diagnostic aspects. Vaginal tumorectomy was curative, and no recurrence was observed 14 months after the control.

Female↗
PubMedDate not supplied

[The success of maternal feeding with very low birth weight premature infants, singletons and twins: a 10-year experience].

UNLABELLED: There are very few reports about the feasibility of maternal milk feeding in very low birthweight preterm infants (VLBW), especially in twins. Therefore we conducted a cohort retrospective study to evaluate the feeding patterns of the 226 VLBW discharged from our neonatal intensive care unit from 1987 to 1996. Their gestational age was 30 +/- 2.6 weeks, birthweight 1166 +/- 224 g and they were hospitalized for 67 +/- 37 days (means +/- 1 SD). Of the 226 VLBW 49% were males, 39% had birthweight below 10 degrees centile for gestational age and 56% were born to non-residents in our area. There were 181 single births and 45 (20%) multiple births, of which 16 from pregnancies with 3 or more fetuses. Of the total cases 22% were discharged feeding maternal milk (MM) exclusively and 21% on mixed-feeding, maternal + formula milk (FM). Percentages were respectively 23% and 18% for single newborns, 11% and 29% for twins. Singletons and twins were discharged on FM with comparable percentages (59 and 60%). With passing years we have noticed a significant increase (chi square for linear trend < 0.01) for maternal milk feeding. In the last 2 years 49% of singletons and 38% of twins were discharged on MM, 14% and 24% on MM + FM, and only 37% and 38% on FM only. Between singletons and twins there were no statistically significant differences as far as feeding at discharge is concerned. CONCLUSIONS: most mothers, if correctly informed and encouraged, are able to breast-feed, exclusively or partially, their VLBW offspring, including twins, in the first months of life.

Breast Feeding↗