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Biomedical subjects

F Mendelsohn

Publications and source records attributed to F Mendelsohn.

8 recordsLinked to original sources
PubMed1994

Strychnine-binding proteins in intestinal cells: novel brucine binding site with binding affinities for alkaloids.

The purpose of this work was to define the pharmacology of an intestinal epithelial [3H]strychnine binding site. Strychnine, brucine, verapamil and desmethoxyverapamil bind to small intestinal mucosal homogenates with nanomolar affinity at a site not related to the strychnine receptor, which is in the spinal cord. The antidiarrheal agents, fluperamide and loperamide, and several alkaloids have an order of magnitude lower affinity. Agents that bind to cytochrome P450IID6 also displace [3H]strychnine binding, which implies that the binding site may have some properties similar to the catalytic site of this cytochrome P450 enzyme.

ATP Binding Cassette Transporter, Subfamily B, Mem↗
PubMed1982

Training for independent living unit: its function in a rehabilitation convalescent setting.

This article describes a Geriatric Self-Care Unit in a 92 bed Rehabilitation Convalescent Hospital. Ten beds are set aside for this unit. The overall goal of the Self Care Unit (S.C.U.) is to facilitate the patients' discharge into the community. This pilot project has been in effect for six months with 47 patients having completed the program. Results of the program, its problem areas and progress are outlined.

Activities of Daily Living↗
PubMed1976

Acute hemiplegia in children complicating upper respiratory infections. Report of three cases with angiographic findings.

Three children presented with acute onset of hemiplegia following an upper respiratory infection. Angiography revealed irregulaities, beading, and slow flow of a peripheral branch of a middle cerebral artery. In addition, one child had narrowing of the cervical segment of the internal carotid artery. An inflammatory arteritis of the cervical internal carotid artery is presumably the site of the formation of cerebral emboli.

Acute Disease↗