PubMed Health⌕ Search

Biomedical subjects

F Menegoz

Publications and source records attributed to F Menegoz.

24 records · Page 2Linked to original sources
PubMed1992

[Epidemiology of testicular cancer].

Testicular carcinoma is a rare disease, with an incidence ranging from 0.2 (Blacks in Connecticut) to 7.8 (Denmark) in the World, and ranging from 2.5 to 4.3 in French Cancer Registries. An increase among young men has recently been described in Denmark and in England (Mortality Data between 1936 and 1976). Survival is 75% after five years, all histological types combined. No role as a risk factor "per se" has been confirmed for Genetics alone (Twins study in Finland), but a familial RR of 6 has been observed among first degree relatives of testicular carcinoma cases. Most interesting is a study by A.R. Moss, showing a RR of 4.4 among cases whose mother on had a breast cancer, as it emphasizes a possible role or hormones for non seminomatous testicular cancer.

Adolescent↗
PubMed1991

[Incidence of colonic and rectal tumors as a function of the urban and rural characteristics of the residential area in the Isère district (1979-1985), France].

From 1979 to 1985, 1443 new malignant tumors of the colon and 1017 of the rectum appear in the departement of Isère (France). Using the urban category of "Zone de Peuplement Industriel et Urbain" (Z.P.I.U), we were able to classify place of residence within 3 strata, according to the proportion of inhabitants of the rural (or urban) type. For both sexes, incidence of colon carcinomas is higher in urban categories than in rural ones. For males, incidence of rectal carcinomas is higher within areas of the rural type. Going from the urban category of the rural one, "urban" being the level of reference. Relative Risks for men are 1,0.9 and 0.6 for the colon, and 1, 1.3 and 1.2 for the rectum. For women, RR's are 1,0.8, and 0.7 for colon, and 1,1.0, and 0.8 for the rectum. Same results are described in the literature, with higher risks for colon cancers in urban areas. Our results reporting lower incidence for rectal carcinomas in Isère among men, are in contradiction with other results in the literature. This work supports the idea that epidemiology of large bowel carcinomas should focus onto segments. Second, when categories of residence allow it, it is worthwhile looking at gradients that bring more information on the relation, than the simple dichotomy: urban versus rural.

Colonic Neoplasms↗
PubMed1990

[Critical analysis of a clustering method applied to the study of geographic distribution of cancer].

Cancer registration permits to elaborate atlases that describe the spatial distribution of incidence within the registration area. The division of this area in small units is usually an administrative one, leading a wide range of unit sizes. Hence, results of indirect standardization are often difficult to interpret, due to the large variability of the observed cases. We used Huel's method (1986), which is based on the grouping of contiguous geographical zones that have the same incidence level. Here are displayed the results for cancer incidence within the "département de l'Isère" (France). We focus on method mechanisms and on the impact of the choice of the risk level.

Cluster Analysis↗
PubMed1986

Reproductive history and intrapartum fever.

Washington State Birth Registry data of the years 1980-1982 of 803 women with intrapartum fever, who gave birth to a singleton, and of 1,714 control women without such diagnosis selected at random from the child-bearing population were studied for risk factors and maternal and neonatal outcome variables. Cases were significantly more often less than 21 years old, nonwhite, unmarried, nulligravid, and nulliparous than controls, and had significantly shorter gestational ages and longer birth intervals. The risk of intrapartum fever was higher in nulliparous than in nulligravid women [adjusted odds ratio (OR) 4.0 and 2.3, respectively]. This risk difference led to the discovery of increased fetal and perinatal losses prior to the pregnancy under study: cases lost 160 of 390 (41%) previous pregnancies while controls lost 142 of 1,180 (12%; OR = 5.1; p less than 0.001). In a matched analysis, spontaneous abortions (less than 20 weeks gestation) immediately preceding the pregnancy under study were found to increase the risk of intrapartum fever by 2.7 times.

Abortion, Spontaneous↗
PubMed1983

Cancer registries: their interest and practical problems.

Cancer registries record all new cases of cancer within the population they survey. Thus they provide accurate regional measurements of cancer morbidity and mortality and their geographical distribution. This form of epidemiology allows the study of regional variations and alterations with the passage of time. It also allows the study of environmental factors that might cause cancer. The work of the French regional cancer registries is described to illustrate these points. The problems of running a cancer registry are also set out and suggestions are made for future organization. The statistics gathered by such registries indicate possible methods for the early detection and treatment of some cancers and provide evidence of the long-term effects of all kinds of therapy. The socio-economic aspects of cancer can also be measured by the registry, thus providing valuable data for use in the planning of health care in any community.

Epidemiologic Methods↗