[Primary chronic polyarthritis in childhood].
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Biomedical subjects
Publications and source records attributed to F Mignone.
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The nosological independence of psoriatic arthritis is discussed in the light of the literature. The clinical and laboratory pictures of infantile psoriasis and PCP are described. Three cases of infantile psoriatic polyarthritis are presented and attention is drawn to the difficulty of diagnosing this condition in children. Longitudinal assessment of the possibility of early onset on the part of forms becoming evident during adulthood is envisaged.
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Changes in serum LDH in AAR, Sydenham's chorea and purpura rheumatica and their significance were investigated in 103 cases observed at the 1st Paediatrics Clinic, University of Turin. A search was made for relation between such changes and the laboratory parameters in rheumatism. The data showed that blood LDH can be profitably determined in the diseases considered.
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A study was made of changes in body fluid parameters of rheumatism following treatment with sulphoadenosine-methionine and classic forms of management. Particular attention is drawn to improvement of the serum electrophoretic picture (especially in the case of alpha 2 and gamma-globulins) with respect to untreated control group. Note is also taken of the drug's positive influence on liver function, particularly with regard to lactate hydrogenase, compared with the variations in such parameters in the control group.
Problems related to the inhalation of foreign bodies by children are discussed and two cases with unusual symptom pictures are presented. It is shown that some instances of acute respiratory or cardiorespiratory insufficiency of unknown origin in infancy may in fact be attributable to a foreign body in the respiratory system.