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Biomedical subjects

F Milazzotto

Publications and source records attributed to F Milazzotto.

At least 55 records · Page 3Linked to original sources
PubMed1981

[Pharmacological therapy and prevention of recurrent ventricular tachycardia].

Treatment of recurrent ventricular tachycardia (RVT) is still difficult, as far as choice of antiarrhythmic agents, dosage, associations and statement of their effectiveness are concerned; the Authors report their experience on twelve cases of RVT. The diagnosis of ventricular tachycardia was confirmed by esophageal electrograms in four cases and by intracardiac recordings in two cases. Patients were controlled by clinical observation, continuous electrocardiographic monitoring and several recordings. Ambulatory electrocardiographic monitoring was carried out in ten patients. Two patients left the hospital spontaneously; therapy was found to be effective in the remainder. Four patients were treated with quinidine plus betablockers, for cases with quinidine plus amiodarone. The results of long-term follow-up suggest that combined pharmacological therapy with drugs of different classes may be successful in preventing recurrences of ventricular tachycardia. The Authors think that careful choices of adequate therapeutic programs and rigid criteria for the evaluation of results should be planned in apparent refractory RVT, before referring to invasive procedures.

Adult↗
PubMed1978

[The course of hypertrophic obstructive cardiomyopathy. A preliminary study of 40 cases (author's transl)].

The course of hyperthrophic obstructive cardiomyopathy in 40 patients was studied. The average follow-up of the patients (anamnestic and prospective) was 8 years. The age of the first diagnosis, the age of the first observation and the age of the detection of the first symptom, were considered. A prospective follow-up study was carried out in 31 patients, the average period of observation being 8 years. Functional capacity modifications, symptoms, clinical and electrocardiographic signs and the mortality rate were analyzed. Functional class unchanged in the most part of the patients; the overall mortality was 16% with high incidence of sudden and unexpected death. From our results it appeared that the prognosis could be related to the old age, heart failure and arrhythmias.

Adolescent↗
PubMed1978

[A study of the natural evolution of hypertrophic obstructive cardiomyopathy. Analysis of 100 cases (authors' transl)].

The authors present a study of the course of hypertrophic obstructive cardiomyopathy (C.I.O.), diagnosed both through noninvasive (52) and invasive (48 cases) techniques, in 100 patients. The average period of observation (prospective and retrospective) was 8.2 years; in 68 cases prospective inquiries were carried out over an average period of 4.6 years. In 80% of the cases the first symptoms occurred when the patient was under 40, while the first diagnosis and period of observation usually took place between the ages of 20 and 50. The results of this study confirm that CIO is an illness with a slow evolution; the following facts emerge: a) considerable stability of the symptoms; b) low yearly mortality rate (1.8%); c) high rate of survival 10 years after the first onset of the symptoms. The most frequent cause of death is usually sudden, which leads to the supposition that one of the most important elements for prognosis is the identification and treatment of arrhythmias.

Angina Pectoris↗
PubMed1978

[Analysis of Luciani-Wenckebach periodism in A-V node. I. Typical features (author's transl)].

Electrocardiograms of 20 patients developing Wenckebach A-V block duting atrial pacing and 20 with spontaneous Wenckebach block were reviewed to determine the frequency of typical features of classical Wenckebach periodicity. Few cases only met all six typical criteria. Cases with long cycles with conduction ratios of 5/4, with Wenchkebach point less than 130 min, and with first greater than A-H 110 msec were the most likely to show typical features. The implications of these observations are discussed on the basis of modern hypothesis of electrophysiological mechanisms of Wenckebach periodism.

Atrioventricular Node↗
PubMed1978

[Analysis of the Luciani-Wenckebach phenomenon in the A-V node. II. Relationship between conduction and recovery times].

We have studied 20 cases Wenckebach A-V block by atrial pacing. The relationships between conduction time and recovery time of N. AV Wenckebach point, basal A-H time and A-H time of first cycle beat were analysed. No correlation was found between W point, basal A-H and A-H of the first beat by analysing the A-H = f (H-A) we found different curves which occur when the first A-H is longer or shorter than 110. These data were discussed on the basis of modern hypotheses of electrophysiological mechanism of Wenckebach periodism.

Electrocardiography↗
PubMed1977

[Considerations on the diagnostic and therapeutic approach to hypertrophic subaortic stenosis (author's transl)].

Several physiopathological, diagnostic and therapeutic considerations have arisen from the observation of an operated case of hypertrophic subaortic stenosis associated with mitralic insufficiency and fibrosis of the interventricular septum. Keeping in mind the variability of the clinical pictures and the functional and anatomical factors which determine the clinical picture of the hypertrophic subaortic stenosis, it is concluded that a careful, unbiassed, clinical approach is necessary to determine the therapeutic procedure in each individual case.

Adult↗
PubMed1976

[Systolic time intervals in obstructive hypertrophic cardiomyopathy. The effects of adrenergic beta-stimulation and beta-blockade in 38 cases (author's transl)].

The authors report on the behaviour of systolic time intervals, studied with a noninvasive poligraphic technique, under normal conditions, after adrenergic beta stimuls (orciprenaline) and successive beta blocker (pindolole) in 38 patients with obstructive cardiomyopathy. Under normal conditions, the authors observed a marked dispersion of PEP and TEVS data, which have, however, average normal values. The IPEP was reduced in 29% of cases, was normal in 47.3% and raised in 23.7%; the ITEVS was reduced in 55.2% of cases, was normal in 21.1%, raised in 23.7%; the PEP/TEVS was reduced in 23.7%, normal in 31.6% and raised in 44.7%. The beta stimulation demonstrated a number of behaviour patterns: the most frequent cause was a reduction of PEP in the cases where it had been raised or where it had remained within normal limits, an increase of TEVS in the cases where it had been diminished or normal, a reduction of the PEP/TEVS correlation where these values were increased or normal. The beta blocker, followed by beta stimulus, brought on variations opposite from those of the beta stimulation. Thus, one can consider the hypothesis that the possible behaviour patterns and combination of PEP and TEVS result from different anatomical and functional expressions that can become obstructive cardiomyopathy, according to the seriousness of the obstruction, the ventricular compliance and the contractility.

Adult↗