Biomedical subjects
Publications and source records attributed to F Mitschke.
A technique is introduced which allows us to extract information on the solitonic content from a nonlinear wave. Its applicability is not as narrowly restricted as that of inverse scattering theory; therefore, it works in situations that could not be studied before. As an example we identify and demonstrate a higher order dispersion-managed soliton.
Attractive interaction of dark dispersion-managed (DM) solitons is observed numerically. For certain initial separations chains of bound dark DM solitons are found. The chains can have various lengths (up to 12 solitons are shown), and the nearest-neighbor separations can take several values-all the same or mixed.
A bound state of temporal solitons in optical fibers is predicted numerically and demonstrated experimentally. It is appropriately described as a pair of bright solitons, bound together by a dark soliton. This structure exists only in dispersion-managed fiber and is different from bound solitons in fiber lasers.
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In many biological systems information is transferred by hormonal ligands, and it is assumed that these hormonal signals encode developmental and regulatory programs in mammalian organisms. The specificity of the biological response on activation by a hormone has so far been located within the interaction of a specific conformation of the ligand with the corresponding receptor structure. According to these classical explanations, the constant circulating hormonal pool described by the rate of its production and metabolic clearance is a major determinant of this interaction. Recently it has become apparent that hormone pulses contribute to this hormonal pool. Phase-space analysis of dynamic parathyroid hormone (PTH) secretion allowed the definition (in comparison to normal subjects) of a relatively quiet "low dynamic" secretory pattern in osteoporosis, and a "high dynamic" state in hyperparathyroidism. We now investigate whether this pulsatile secretion of PTH in healthy humans exhibits characteristics of low-dimensional deterministic chaos. Our findings suggest that this indeed appears to be the case. PTH secretion thus seems to be a first example of a chaotic hormonal rhythm in human physiology.
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