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F Mitu

Publications and source records attributed to F Mitu.

24 records · Page 2Linked to original sources
PubMedDate not supplied

[Chronic myocardial infarction. Clinical symptoms in elderly patients].

UNLABELLED: Although there is an increasing prevalence of coronary heart disease at the old age, the frequency of chronic myocardial infarction seems to be less in favour of other forms of manifestation. The objective of the study was the assessment of the clinical features of patients with chronic myocardial infarction at a population of coronary patients over 65, admitted in the Department of Cardiac Rehabilitation. METHODS: There have been selected patients over 65 years with ischaemic heart disease: 29 with chronic myocardial infarction (Group A), and 31 with other forms of coronary heart disease (Group B). There were analysed cardiovascular risk factors, symptoms, lipidic profile, echocardiographic findings. RESULTS: Mean age of the groups A and B are 69.9 +/- 4.7 and respectively 71.6 +/- 4.9. Arterial hypertension is more frequent at group B (28/31 vs 22/29, p=0.05); at group A there is a higher rate of smoking (13/29 vs 8/31, p=0.007) and diabetes mellitus (12/29 vs 3/31, p=0.001). Dyspnea is prevalent at group B (26/31 vs 21/29, p=0.01), and the resting heart rate is greater at the same group (89 +/- 19/min vs 74 +/- 14/min, p=0.02). Group A associates more frequent atherosclerotic neurologic and peripheric disease (7/29 vs 5/31 p=0.05 and respectively 6/29 vs 4/31, p=0.01). Although the ejection fraction has similar values (53.9 +/- 10% at group A and 53.8 +/- 14% at group B), the regional contractility abnormalities are more frequent at group A (17/29 vs 11/31, p=0.005). CONCLUSIONS: Old patients with chronic myocardial infarction are especially male gender, associate smoking, diabetes mellitus, other atherosclerotic neurological and peripheric diseases; the regional contractility disturbances are more prevalent at this group.

Aged↗
PubMedDate not supplied

[Carotid atherosclerotic alterations revealed at ultrasonographic examination in patients with coronary heart disease].

UNLABELLED: Carotid ultrasound examination is a noninvasive method with large indications in the evaluation of atherosclerotic lesions at cardiac patients. The aims of the study were: the ultrasound assessment of extra cranial carotid system at patients with coronary heart disease; relationship with the cardiovascular risk factors, lipid profile and echocardiographic data. METHODS: There were studied 47 patients with coronary heart disease (angina, myocardial infarction, ischemic cardiomyopathy, CABG). The evaluation included cardiovascular risk factors, clinical examination, serum lipids and glucose, echocardiographic data. The ultrasound examination of the carotid arteries included the measurement of the diameter and intima-media thickness (IMT) of the common carotid arteries, the presence and location of atherosclerotic plaques and the presence and severity of carotid stenosis. RESULTS: There was a significant increase of the diameter and IMT with age (p=0.009 respectively p=0.05). Males had a greater medium diameter than women (7.8 +/- 0.9 mm vs. 7.3 +/- 0.8 mm, p=0.04). There was no significant relationship between the cardiovascular risk factors (smoking, arterial hypertension, diabetes mellitus, dyslipidemia) and IMT. The thickness of the interventricular septum (at the echocardiographic examination) correlated with the IMT (p=0.03). All the patients with myocardial infarction revealed carotid atherosclerotic plaques and most of the smokers had carotid plaques (88.9% vs. 44.8%, p=0.03). Patients with carotid plaques were older (60.9 +/- 10.1 vs. 54.8 +/- 6.1, p=0.02). CONCLUSIONS: The incidence of carotid atherosclerosis increases with age; the carotid diameter is greater at males and older patients; IMT is influenced mainly by age; carotid plaques are present mainly at older patients, at smokers and those with myocardial infarction and can be considered an additional risk factor for vascular

Adult↗
PubMedDate not supplied

[The effect of rehabilitative treatment on left ventricular performance in myocardial infarct patients in the convalescent phase].

There have been studied the left ventricular performance at 71 patients (66 B/5 F) with myocardial infarction during the convalescence period, admitted in the Department of Clinical Rehabilitation in a period of time between 01.01.1992-31.10.1993. Mean age was 49.9 +/- 4.3 years. Most of the patients had antero-septal (33 patients--46%) and posteroinferior (29 patients--41%) myocardial infarction. The left ventricular performance was assessed by the study of exercise electrocardiography (TTI), of the systolic intervals using the Weissler equations and echocardiography (M-mode and 2D). After the period pf training (21 days), we saw a significant reduction of TTI at the same step of the test. The systolic intervals significantly modified after the training were PEVS (p < 0.025), PEP/PEVS (p < 0.025), EF (p < 0.025). EF and SF measured echographically do not indicate significant differences after the training. There are not important improvements of the wall motion disorders at the end of the period.

Adult↗
PubMedDate not supplied

[The clinico-epidemiological premises for antioxidant prevention and treatment in chronic myocardial infarct].

The improvement of therapeutic and recoverable proceeding to chronic myocardial infarction (IMC) imposes a complex epidemiological estimation of the global cardiovascular risk, of their clinical and biological status. The retrospective evaluation of the risk factors (RF) by epidemiological methods, in 38 hospitalized prevalence of both constitutional and behavioral factors, and the quantification of the risk state, according to graph Euro 194, has pointed on the fact that 50% of IMC cases have presented a global risk of 10-20%. That justified the application of a preventive conduct in order to continually neutralize the associates FR. The biochemical determinations have allowed to frame the dyslipidemic patients, according to the ARCOL classification in the classes D (29.2%), E (25.0%) and B (20.8%) with direct implication in the adopted therapy. The colorimetric dozing with thyo-barbituric acid of the malonly dialdehyde (MAD) each is a product of the lipidic peroxidation, as well as the interpreting or correlation of the registered values with an evolutive clinic stage, and with the existence of some existing diseases (diabetes, chronic hepatitis etc.) along with signification of other dismethabolical parameters (cholesterol, triglycerides, LDLc, apoB) have confirmed the necessity of a complex therapy, including an antioxidative treatment, having the role to directly inhibit or exclude the free radicals resulted after the oxidative stress of the infarct.

Antioxidants↗
PubMedDate not supplied

[The role of physical training in lipid metabolic parameters in patients with chronic myocardial infarct].

OBJECTIVES: The aim of the study is to follow the variation of some parameters of the lipidic metabolism, during physical training, at patients with chronic myocardial infarction. METHODS: Among 132 patients with chronic myocardial infarction, we selected 22 patients, mean age 47.4 +/- 6.08 years from which 18 followed supervised physical training a period of 3-6 months. There were determined before and at the end of the interval, the following parameters: serum lipids, serum cholesterol, HDLcol, LDLcol, triglicerids, apolipoproteins A,B, Apo B/A ratio. The statistical comparison has been made for each parameters, by univariate and multivariate analysis. RESULTS: HDLcol increased significantly in the study group at the end of the interval (from 28.9 mg% to 42.3 mg%, p < 0.001); LDLcol and total cholesterol did not vary. Apo A increased significantly, but Apo B/A ratio did not change. CONCLUSIONS: Physical training altered the lipidic profile by increasing the protective fraction of the cholesterol--HDLcol and Apo A.

Adult↗