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Biomedical subjects

F Modafferi

Publications and source records attributed to F Modafferi.

3 recordsLinked to original sources

Primary leiomyosarcoma of the fallopian tube: a case report.

A primary leiomyosarcoma (LMS) arising from the left fallopian tube in a perimenopausal 48-year-old woman is reported. Primary tubal LMS is an uncommon, exceedingly rare neoplasm, accounting for only a few reported cases so far. To our knowledge, the present case is the 17th tubal LMS reported in the English-language literature. The diagnosis is usually made at the time of laparotomy for a pelvic or adnexal mass or other gynaecological indications. As in ovarian neoplasms, the mainstay of treatment is represented by debulking surgery consisting of total abdominal hysterectomy, bilateral salpingo-oophorectomy, random biopsies, peritoneal washing and excision of all the abdominal tumour masses. Although the approach is radical, the clinical behaviour is very poor. The role of adjuvant radio- or chemotherapy still remains unsolved.

Fallopian Tube Neoplasms↗

Epithelioid cell's uterine leiomyoma uteri. A case report with immunohistochemical study.

In the present report we refer to a rare case of uterine leiomyoma Uteri with epithelioid cells, characterized by an omogeneous light cell's structure and by a lymphangiomatous like histological aspect. An immunohistochemical study was carried out, using both endothelial and cell surface markers, as well as vascular markers. This study has allowed us to exclude the angiogenic origin of the neoplasm. It has, furthermore, revealed how the lymphangiomatous like histological aspect, even though being a peculiar component of the tumor, is to be put in relation with the epithelioid cells' layout, which has been evidenced by the immunohistochemistry to be of muscular nature.

Biomarkers, Tumor↗

Pseudomixoma peritonei: a case report.

Pseudomixoma Peritonei (PMP) is an uncommon neoplasm characterised by mucinous ascites and multifocal amorphous mucous substances involving the peritoneal surface, omentum and bowel loops. Although the origin of the Pseudomixoma Peritonei is still unclear, it could be due to the perforation of an ovarian mucinous cystoadenoma or an appendiceal mucocele. The further pelvic dissemination of the endotumor material, which adhere itself into the peritoneal surface, may induce an intra-abdominal transformation of the peritoneal mesothelium into mucin-producing tissue. A case of Pseudomyxoma Peritonei (PMP) which occurred in a young woman is reported.

Adult↗