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Biomedical subjects

F Moulin

Publications and source records attributed to F Moulin.

At least 73 records · Page 4Linked to original sources

Twenty-five cases of relaxing retinotomy using a nanosecond Nd Yag laser (Yag-retinotomy).

The results of the first 25 retinotomies performed with a nanosecond Nd Yag Laser (Nanolas, Biophysic Medical) between September 1986 and July 1987 are described. This technique was chosen in order to avoid additional surgery and anesthesia in patients requiring a relaxing retinotomy. Treated eyes were usually filled with silicone oil. Simple contact anesthesia and a three-mirror lens were sufficient. Energy was set at 10-15 mJ, 50 Hz burst mode, 10 degrees cone angle. The aim of the treatment was to eliminate a residual inferior traction, to remove silicone oil (19 cases), or to obtain reapplication at the posterior pole. Results were positive in 18 cases and negative in 7, but unsuccessful Nd Yag laser treatment may be corrected with surgical retinotomy. The main complication is hemorrhage, which usually subsequently decreases and does not affect the prognosis.

Adolescent↗

Memory complaints in the elderly: a study of 367 community-dwelling individuals from 50 to 80 years old.

State of memory was evaluated by a Memory Clinic in 367 community-dwelling patients aged from 50 to 80. They performed an exhaustive subjective evaluation including: severity of memory complaint, social status, activity scale, subjective Memory score, Zung's anxiety and depression scales and Well Being Questionnaire. Objective memory performance was evaluated by a complete memory scanning leading to a Global Objective Memory Score. No relationship was found between severity of memory complaints and age, sex, educational level, marital status, living alone or in family, and memory tests performance. More severe complaints were reported in people with poor social network, negative stereotypes on aging, and poor affective status. A strong correlation was found between severity of memory complaints and scores in self-reporting depression questionnaire, even in people with low depression scores.

Aged↗

Late failures of trabeculoplasty.

The effects of trabeculoplasty, or Argon laser trabeculoretraction (A.L.T.R.) resulting from a study pursued over two years in 194 eyes, over 3 years in 45 eyes, and over 4 years in 22 eyes, show early and late failures. 151 phakic patients (76 women and 75 men aged between 25 and 93 with an average of 67 years) were treated. After a follow-up of two years we have an intra-ocular pressure (I.O.P.) drop of 6.93 mmHg and a failure rate of 28%; after a follow-up of 3 years the I.O.P. drop is 6.30 mmHg and the failure rate 36%; after a follow-up of 4 years the I.O.P. drop is 7.87 mmHg and the failure rate 41%. The initial medical treatment could be decreased in less than 50% of the cases. The frequency of failure is more important in the presurgical glaucoma with an intra-ocular pressure higher than 28 mmHg and submitted to maximum tolerated medical therapy. A.L.T.R. gives good results in combined mechanism glaucoma and after failure of trabeculectomy; a two-year follow-up shows similar efficacy in primary open angle glaucoma (P.O.A.G.) and in pigmentary glaucoma, bad results in myopic or in aphakic glaucoma (12 cases not included in this study) and 'escape' in pseudo-capsular glaucoma. The total study conducted over 4 years shows 10% new failure cases per year.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Classification of diabetic retinopathy.

A review of the literature on the classification of diabetic retinopathy shows that a consensus of opinions is not attained. Therefore it is impossible to compare the results of different works. Most of the classifications are based on purely anatomical criteria (ophthalmoscopic or photographic). The authors propose to base the classification of diabetic retinopathy on angiographic criteria. They consider that only fluorescein angiography can take into consideration the functional evaluation of the retinal circulation with unquestionable pathogenic correlation and adapted treatment: edematous diabetic retinopathy corresponds to capillary dilatation and ischemic diabetic retinopathy corresponds to capillary occlusion. Macular diseases are classified according to these same criteria.

Diabetic Retinopathy↗

[Adverse effects and complications of argon laser trabecular retraction: practical results].

Argon laser trabeculoplasty is learned and used much more easily than filtration surgery. This explains the danger of its being abusively employed, as well as the existence of complications such as an aggravated glaucoma condition (1 to 3% of the cases). In 253 eyes afflicted with various forms of chronic open angle glaucoma with follow-ups ranging from at least 6 months to 4 years, the following complications were disclosed: 3% of the cases required treatment for severe anterior uveitis; anterior synechiae occurred in 23%, including one case of circular anterior synechiae and 4 other cases in which acute angle closure glaucoma developed several months later; trabecular hemorrhage in 6%; post operative intra ocular pressure elevation in 13%. This last complication is the most dangerous especially in advanced glaucoma: it very frequently happens during the first post operative hours in the absence of preventive treatment and it can arise up to three weeks after the procedure. In 33 cases upon 253 (13%), the pressure increase, despite a systematic preventive treatment, ranged from +3 mmHg to +16 mmHg above the baseline level in more than two thirds of these particular cases (+5 mmHg in only 7.5% of the cases and +9 in only 3.5%). In 59 eyes treated by less intensive trabeculoplasty (50 burns upon 180 degrees trabeculoplasty ring), the pressure increased in only 3.4% of the cases but the long term efficacy was reduced. Argon laser trabeculoplasty complications are less numerous than those of surgery, but some of them, i.e. intra ocular pressure elevation, can be very serious and must lead to a study of the risk-benefit ratio corresponding to the glaucoma stage which is to be treated.

Follow-Up Studies↗

Study of the first hundred phakic eyes treated by peripheral iridotomy using the N.D. Yag laser.

Performing a peripheral iridotomy with a ND Yag laser is a simple and efficient technique, with no side effects, no need for anaesthesia other than local and no surgical opening of the eye, with all the risks it entails. Out of 100 cases, 100% were a success from a technical point of view, and we observed no lesion of the lens which could have caused cataract. This out-patient technique, causing fewer complications than with Argon laser, can be used on any patient, whatever the age and the state of the angle, who has to be treated by peripheral iridotomy. The Neodymium Yag laser (ND: Yag) is a pulsed solid laser (1, 2, 3, 8, 29, 31). It cuts tissues (photodisruption) by means of a shock-wave produced by optical breakdown (plasma formation). Its effect is different from that of the Argon laser which burns tissues (photocoagulation). The present study, of 100 cases, deals with the use of ND: Yag in peripheral iridotomies.

Adult↗

Trabeculoperforation? Trabeculoretraction? Trabeculoplasty? Review of the various designations used for laser treatment in primary open-angle glaucoma.

A historical recall and an attempt to simplify the numerous terms used to designate laser treatments for primary open-angle glaucoma (POAG) are presented. There are two main types of laser treatment for POAG involving two entirely different procedures. The first one, contemporary with the beginning of laser photocoagulation, imitates the action of the scalpel, namely goniotomy ab interno or trabeculotomy ab externo. The goal of this early procedure was to produce a through and through trabecular hole but instead of the cutting edge of the knife, it uses the explosive effect of the laser. This procedure has been given numerous names. Among the most frequent ones, we find: 'laser trabeculopuncture', 'laseropuncture', 'goniopuncture', 'laser trabeculectomy', 'laser trabeculotomy', 'laser trabeculopexy'. We prefer to gather them under an explicit generic term: 'laser trabeculoperforation'. The results of this procedure have been very disappointing until now, particularly with conventional lasers, e.g. continuous-wave argon laser, owing to the predominance of their thermal effect over their explosive effect and also to the great scarring property of the trabecular meshwork. In the second type of glaucoma laser treatment, instead of trying to make a patent hole in the trabecular meshwork, the surgeon seeks to reshape the inner trabecular surface by means of argon laser microscars in order to produce a reversal of the trabecular collapse, which is now considered to be one of the major etiologies of POAG.(ABSTRACT TRUNCATED AT 250 WORDS)

Glaucoma, Open-Angle↗