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Biomedical subjects

F N Ihekwaba

Publications and source records attributed to F N Ihekwaba.

24 records · Page 2Linked to original sources
PubMed1979

Ascaris lumbricoides and perforation of the ileum: a critical review.

Ileal perforation due to typhoid bacilli is the commonest cause of peritonitis in the Tropics. Perforation due to Ascaris lumbricoides is rare. Three cases of ileal perforation believed to be due to A. lumbricoides are presented and the evidence critically reviewed. It is suggested that signs of heavy infestation with A. lumbricoides make a diagnosis of intestinal perforation more likely in a patient with an acute abdomen.

Ascariasis↗
PubMed1978

Splenic abscess in a tropical zone.

Abscess of the spleen is uncommon. The reported incidence varies widely and early observations of an association with tropical fevers are no longer evident. The pathogenesis is ill-understood and diagnosis is difficult and usually late. A careful clinical examination combined with the recent utilization of (99)Technitium scanning and splenic arteriography now permit early diagnosis. Splenectomy is the treatment of choice.

Abscess↗
PubMed1976

Anomalous origin of the left coronary artery from the pulmonary artery with coronary artery steal in adults. Report of two cases and review of the literature.

Patients with anomalous left coronary artery arising from the pulmonary artery rarely survive to adult life. Those who attain adulthood may present with angina indistinguishable from coronary artery disease and are liable to sudden death. Myocardial infarction, though rare in young adults, may occur and may be due to coronary artery steal. Accurate diagnosis requires coronary arteriography. Two further cases of coronary artery steal in adults with anomalous origin of the left coronary artery from the pulmonary artery are presented. In both patients aortocoronary bypass grafting using a reversed autogenous saphenous vein with closure of the origin of the anomalous left coronary artery was successfully performed. This operation provided complete symptomatic relief and may protect patients against the risk of sudden death.

Adolescent↗
PubMedDate not supplied

Tamoxifen in the management of advanced breast carcinoma in Nigerian women.

Twenty-nine Nigerian women with advanced breast carcinoma treated with Tamoxifen (Nolvadex ICI) at a dosage of 20 mg twice daily have been reviewed. Eight of 26 evaluable patients had objective response (31%). No statistically significant association was found between response rate and menopausal status, previous chemotherapy or disease free interval. The drug was well tolerated with a low incidence of side effects. This study suggests that Tamoxifen is a useful drug in the adjuvant management of patients with advanced breast carcinoma in Nigeria.

Adult↗