Biomedical subjects
Publications and source records attributed to F N Martin.
Thirty unsophisticated participants with normal hearing were paid to simulate a hearing loss according to their success in "deceiving" the examiner. The behaviors that these "malingerers" manifested are described. A post-examination interview revealed the strategies used by these participants, which may reflect those strategies used by patients who truly attempt to feign a hearing loss.
Twenty individuals were tested to determine the occlusion effect caused by supraaural earphones and by insert earphones with shallow and deep insertion of its foam eartip. The bone-conduction oscillator was placed both on the forehead and the mastoid. It was concluded that using deeply inserted earphones is the most practical way in which to carry out clinical bone-conduction measurements.
A proposal is made that 15 dB HL, rather than 25 dB HL, be considered the upper limit of normal hearing sensitivity. This recommendation is based on an explanation of the change from an earlier philosophy and the fact that so many people with hearing levels that average less than 25 dB HL consider themselves to have hearing difficulty. Such reclassification of people with slight to mild hearing losses would dignify their clinical complaints and aid in counseling that would assist them with their hearing difficulties.
The efficacy of a screening procedure for detecting nonorganic hearing loss using standard audiometric instrumentation was examined. Thirty normal-hearing subjects' responses to continuous and standard and lengthened off-time pulsed tones, using an ascending-descending method, were compared. Subjects were asked to respond to test stimuli in normal-hearing and simulated hearing loss conditions. Data show that there are clinical and statistical differences between subjects' response patterns in the normal-hearing condition as compared to the feigned hearing loss condition. The procedure is offered as a simple method of screening for nonorganic hearing loss.
Twenty subjects with normal hearing and 15 subjects with mild-to-moderate sensorineural hearing losses were tested with eight lists of words using monosyllabic pronunciation to determine word recognition scores. Four of the lists were taken from Northwestern University Test No. 6 and four were simply made up by randomly selecting words from a dictionary. All of the word lists were used to determine performance-intensity functions. No clinically meaningful differences were observed among the lists.
A 5-page questionnaire was sent to 500 audiologists who were randomly selected from the directory of members of the American Academy of Audiology to assess the clinical practices most commonly used by certified audiologists in the United States. Survey content was limited to only those practices and procedures routinely used by audiologists across the nation. The current results were then compared to those obtained in similar studies conducted in 1971, 1972, 1978, 1985, 1989, and 1994 to determine which clinical procedures are being retained, modified, or replaced.
Sound pressure levels in the external auditory canals of 50 subjects were measured at 2000 and 4000 Hz with a bone-conduction vibrator on the forehead, the mastoid ipsilateral to the probe microphone, and the mastoid contralateral to the probe microphone. A plug was placed in the external auditory canal to minimize sound pressure levels in the external auditory canal produced by the osseotympanic mode of bone conduction. Results suggest that clinically significant false air-bone gaps (greater than 10 dB) due to acoustic radiation into the concha from the bone-conduction vibrator are most likely to occur at 4000 Hz when the bone-conduction vibrator is placed on the mastoid of the test ear. To minimize the possible confounding effects of acoustic radiation, the bone-conduction vibrator may be placed on the forehead or the mastoid contralateral to the test ear while masking the nontest ear.
This study was primarily designed to explore the job satisfaction of audiologists in the United States. A total of 285 audiologists completed background questions, rated statements, and answered questions about their job satisfaction. Through the use of multiple regression analyses, six statements were identified as being statistically significant in predicting job satisfaction. The most important factor was in the category of challenge.
Determination of tactile bone-conduction (BC) thresholds is essential to provide proper diagnosis of individuals with profound hearing loss. In this study, auditory and tactile BC thresholds were compared using three oscillators: the Radioear B-70-A, B-71, and B-72 with mastoid and forehead placement. Subjects included 12 adults with normal hearing (to establish auditory thresholds) and 12 adults with profound sensorineural hearing loss (to establish tactile thresholds). All 24 subjects were tested at octave intervals from 250 through 4000 Hz. As demonstrated in previous studies, tactile thresholds were lower for the low frequencies. Some differences in tactile thresholds were evinced as a function of different oscillators. One fact that emerged from this study is the lower tactile threshold with forehead placement as compared to the mastoid. While ostensibly a disadvantage to forehead BC testing, there are some clinical advantages to be gleaned from this discovery.
Pulsed-field gel electrophoresis (PFGE) of isolates of Pythium oligandrum with linear mitochondrial genomes revealed a distinct band in ethidium bromide-stained gels similar in size to values estimated by restriction mapping of mitochondrial DNA (mtDNA). Southern analysis confirmed that these bands were mtDNA and indicated that linear genomes were present in unit-length size as well as multimers. Isolates of this species with circular mtDNA restriction maps also had low levels of linear mono- and multimers visualized by Southern analysis of PFGE gels. Examination of 17 additional species revealed similar results; three species had distinct linear mtDNA bands in ethidium bromide-stained gels while the remainder had linear mono- and multi-mers in lower amounts detected only by Southern analysis. Sequence analysis of an isolate of P. oligandrum with a primarily circular mitochondrial genomic map and a low amount of linear molecules revealed that the small unique region of the circular map (which corresponded to the terminal region of linear genomes) was flanked by palindromic intrastrand complementary sequences separated by a unique 194-bp sequence. Sequences with similarity to ATPase9 coding regions from other organisms were located adjacent to this region. Sequences with similarity to mitochondrial origins of replication and autonomously replicating sequences were also located in this region: their potential involvement in the generation of linear molecules is discussed.
Sound pressure levels (SPLs) were measured in the external auditory canals (EACs) of 16 subjects with normal hearing and normal middle ear immittance. SPLs were the result of bone-conduction (BC) stimulation at 500, 1000, 2000, and 4000 Hz, with the oscillator placed either on the forehead or on the mastoid process. At 1000, 2000, and 4000 Hz, significantly higher SPLs were measured when the head was stimulated from the mastoid than from the forehead. When SPLs were compared between right and left EACs, forehead placement of the oscillator produced no interaural differences, while mastoid placement resulted in significantly greater EAC SPLs ipsilateral to the oscillator at 2000 and 4000 Hz. We conclude that forehead placement of a BC vibrator may help to lessen the (unwanted) contribution of the EAC to measurements of hearing sensitivity by BC.
To determine contemporary thinking regarding initial counseling of hearing-impaired adults 500 questionnaires were mailed to otologists and otolaryngologists and 500 to clinical audiologists. Usable questionnaires total 136 for the former group and 266 for the latter. Some significant differences were found in the ways clinicians saw themselves as counselors and in the needs they perceived their patients as having. Respondents reported experiencing various methods of training and possessing diverse attitudes about the effectiveness of their preparation as counselors during their professional training.
Four circular plasmids, with a monomer size ranging from 3.2 to 4.94 kb, have been identified in isolates of P. aphanidermatum (two different plasmids), P. torulosum, and an unidentified echinulate isolate. The mitochondrial location has been confirmed for three of the plasmids. Each fungal isolate contained a single plasmid, present in both monomeric and oligomeric forms; plasmid monomers were present as open circles and as supercoiled forms. Restriction maps of the plasmids were dissimilar. Hybridization studies using cloned plasmids revealed no DNA sequence similarity among the different plasmids or between the plasmids and the nuclear or mitochondrial genome of the isolates from which they were recovered. Hybridization of labeled plasmid DNA to Northern transfers of mitochondrial RNA for two isolates indicate that what appears to be the predominant RNA transcript is unit length in size. For three isolates, the plasmid was retained following subculturing and was present in all asexual and sexual single-spore progeny evaluated. For one isolate of P. aphanidermatum the plasmid was unstable and was lost during subculturing.
Performance-intensity functions for PB word lists were run on 19 normal-hearing subjects and 15 subjects with sensorineural hearing losses. Comparisons were made between standard supra-aural earphones (TDH-49P) and insert phones (ER-3A). Results showed that, at least for the higher sensation levels where word recognition tests are usually performed, the phones may be used interchangeably. Using insert earphones for word recognition tests can have several beneficial effects with respect to cross hearing and masking.
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Since Martin and Sides (Asha, 1985, 27, 29-36) found that only 6% of audiologists reported actually following current ASHA guidelines for SRT testing (Asha, 1979, 21, 353-356), a comparison was made on 36 normal-hearing adults of spondee thresholds (ST) collected following strictly those guidelines (ST1) and by an experimental procedure based on the ASHA guidelines for pure-tone audiometry (Asha, 1978, 20, 297-301) (ST2). A 3-frequency pure-tone average (PTA) was also collected. Since mean HTLs differed by less than or equal to 5 db among ST1, ST2, and PTA, both ST procedures appear equally valid and interchangeable, but ST2 was considerably more efficient, requiring less time (mean savings of 139 sec/ear) and fewer word presentations (mean savings of 15 words/ear). The ST2 procedure may have clinical use with no significant compromise in validity.