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Biomedical subjects

F N Silverman

Publications and source records attributed to F N Silverman.

At least 19 recordsLinked to original sources

Dysplasia epiphysealis hemimelica.

The historical aspects of dysplasia epiphysealis hemimelica are presented in this article along with three cases illustrating some of the problems of understanding and diagnosing a condition. A theoretical discussion of pathogenesis is attached as an example of the kind of argument often presented to Ben Felson when looking for help in understanding radiographic findings. He often indicated the directions for more work, but his knowledge, wisdom, and reasoning powers just as often hit upon a key concept that had eluded us. It is my loss that this article was not written and presented to Ben at a time when we had more available than a file of miscellaneous notes.

Adult

Spondylo-megaepiphyseal-metaphyseal dysplasia: a new bone dysplasia resembling cleidocranial dysplasia.

Eight patients are presented who have a generalized bone dysplasia that resembles severe cleidocranial dysplasia but lacks the cranial and clavicular features of that well-defined condition. Vertebral-body ossification is markedly defective, and ossification centers of the tubular bones are grossly enlarged. These patients also differ from those with variant forms of cleidocranial dysplasia described in the literature. It is suggested that they constitute a separate entity sharing some features of cleidocranial dysplasia, and the descriptive term spondylo-megaepiphyseal-metaphyseal dysplasia is offered as a provisional term until it can be more specifically categorized. The condition appears to be transmitted as an autosomal recessive trait.

Adolescent

Lesions of the femoral neck in Legg-Perthes disease.

Focal destructive lesions of the femoral neck occur in some cases of Legg-Perthes disease and may indicate a potential for marked deformity when healing is complete. Moreover, interventional procedures may aggravate tendencies to final deformity. The lesions should not be confused with infectious or neoplastic destruction. Although their recognition began with the first descriptions of the disease, preoccupation with the changes in the femoral head has directed attention away from them. Five case reports and a review of the literature are presented, with emphasis on the radiographic appearance of these lesions.

Child

Unusual roentgenographic presentation of a congenital cystic malformation of the lung.

We describe here an infant with a large, solitary, fluid-filled lung cyst and hyperinflation of adjacent lung tissue in the same lobe. The combination of a fluid-filled cyst and ectatic emphysema in the same lobe suggests bronchial collapse and airway obstruction as a contributory mechanism for this unusual roentgenographic presentation of a congenital cystic malformation of the lung.

Female

Intussusception in the 1970s: indications for operation.

Eighty-one patients with proven intussusception were treated at the Cincinnati Children's Hospital from 1970-1974. One died. Seven of these had ileo-ileal intussusception, all treated surgically. Seventy-four had colonic components of their intussusceptions. In 58 of these patients (78%), reduction was attempted at barium enema, successfully in 32. Hydrostatic reduction was abandoned and the patient operated upon when the intussusception was not pushed out of the colon, when barium failed to reflux into several loops of ileum, or when there was a large persistent filling defect in the cecum or terminal ileum. Primary operation without barium enema was done in 16 patients. The appearance of intestinal obstruction by abdominal x-ray seemed to give the best warning about the complicated, incarcerated, or gangrenous intussusception. Primary operation is, therefore, advised for the patient with intussusception if there is x-ray evidence of intestinal obstruction. The age of the patient and the duration of his symptoms do not seem important in this regard, except as they correlate with peritonitis or obstruction. For the patient without peritonitis or intestinal obstruction, attempted reduction of the intussusception at barium enema seems safe and effective, regardless of the patient's age or duration of his symptoms.

Barium Sulfate

Thickness of the normal skull in the American Blacks and Whites.

Normal skull thickness has been measured in a general hospital population of 300 blacks and 200 whites in America. In both groups, there is a rapid increase in skull thickness during the first two decades of life, followed by a small uniform increase reaching a peak in the fifth and sixth decades. The sex differences are variable, but in certain age groups the females in both races have significatly thicker parietal and occipital bones than their male counterpart. The frontal bone is thicker in the white male than in the black, and the parietooccipital thicker in the blacks than in the whites. Some suggestions are offered to explain the sex and racial difference noted.

Adolescent