PubMed Health⌕ Search

Biomedical subjects

F Navas

Publications and source records attributed to F Navas.

4 recordsLinked to original sources
PubMed1983

Comparison of the reinforcing properties of zopiclone and triazolam in former alcoholics.

The reinforcing properties of zopiclone (3.75 mg) and triazolam (0.25 mg) and their side effects were studied in a double-blind crossover design, followed by forced choice in 40 volunteers taken from a population of chronic alcoholic inpatients who had just completed withdrawal from alcohol. After initial interview when the physician checked if the inclusion and exclusion criteria were met, patients were submitted to the following assessments: profile of mood states (POMS), ARCI subscales (items of scales No. 452, 129, 125, and 52), drug record form and vital signs, SESI (side effect checklist), preference form, subjective effect scale (subscale 220 of the ARCI), and withdrawal assessment. No difference between the drugs could be found on the POMS, ARCI or in the drug intake. There was a difference in patients' drug preference for triazolam in comparison to zopiclone. Zopiclone, like triazolam, may induce some feelings similar to those obtained with alcohol. Side effects noticed by patients were of mild to moderate degree and harmless.

Adolescent↗
PubMed1982

Comparison of the reinforcing properties of zopiclone and triazolam in former alcoholics.

The reinforcing properties of zopiclone (3.75 mg) and triazolam (0.25 mg) and their side effects were studied in a double-blind crossover design, followed by forced choice in 40 volunteers taken from a population of chronic alcoholic inpatients who had just completed withdrawal from alcohol. After initial interview when the physician checked if the inclusion and exclusion criteria were met, patients were submitted to the following assessments: profile of mood states (POMS), ARCI subscales (items of scales No. 452, 129, 125, and 52), drug record form and vital signs, SESI (side effect checklist), preference form, subjective effect scale (subscale 220 of the ARCI), and withdrawal assessment. No difference between the drugs could be found on the POMS, ARCI or in the drug intake. There was a difference in patients' drug preference for triazolam in comparison to zopiclone. Zopiclone, like triazolam, may induce some feelings similar to those obtained with alcohol. Side effects noticed by patients were of mild to moderate degree and harmless.

Adult↗
PubMed1968

Sampling or intermittency in hand control system dynamics.

A hand control model is proposed. Investigation of the hand's intermittency synchronization shows it corresponds to an input-synchronized sampler rather than the clock-synchronized sampler more typical of engineering systems. A velocity control mechanism, similar to that in an eye tracking system is shown to be absent in the hand. A quantitative transfer function for predictable inputs serves further to define the hand's input adaptive characteristics. Stability margin adjustments of a linear reduced model enabled us to match the available quantitative data. The most exciting result of this study is the evidence for intermittency: a refractory period shown in the short pulse experiment, peaks in the frequency response experiments, and a saccadic sequence of steps in response to an open loop step input and to a closed loop ramp input.

Central Nervous System↗