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F Negre

Publications and source records attributed to F Negre.

10 recordsLinked to original sources
PubMed2002

[Surgical indications for diabetic maculopathy].

INTRODUCTION: The place of surgery in the treatment of diabetic macular edema is still not clearly defined even though the functional benefits of photocoagulation are less than satisfactory. Key words: Diabetic maculopathy, vitrectomy, internal limitant layer, serous detachment, hard exsudates. EQUIPMENT AND METHODS: We conducted a retrospective study on 40 consecutive cases of diabetic patients, each suffering from serious diabetic maculopathy and for whom photocoagulation would be either impossible to carry out or ineffective. Eighty percent of this study sample exhibited solid vitreomacular adhesions at vitrectomy. The internal limitant layer was dissected systematically. In all cases, plugging by perfluorocarbon liquids during the operation helped posterior focal endophotocoagulation. A gas tamponade was used in all cases. In 18 cases, surgical extraction of large intra- and/or subretinal clumps of hard exudates was necessary to replace the posterior pole. RESULTS: The anatomical results were satisfactory in 97.5% of cases. The functional results were good but their interpretation is more difficult: the visual gain varied as a function of the clinical preoperative condition and how recent the condition was. The best results were obtained in edema with tractional predominance. The smallest visual gains were observed in cases of massive macular hard exudates. The most serious complication was a retinal detachment secondary to a parapapillary nasal retinal break occurring at a distance from the operation during a postoperative photocoagulation complement. DISCUSSION AND CONCLUSION: Vitrectomy released both tangential and axial tractional forces found in diabetic macular edema pathogenesis. The extraction of large clumps of exudates allowed us to replace serous retinal detachments and the photocoagulation of capillary anomalies. In addition, removing premacular vitreous body and gaseous plugging seemed to osmotically resorb the posterior pole edema. These surgical results have made us considerably reduce the use of photocoagulation for diffuse diabetic macular edema in the past four years.

Adult↗
PubMed2000

[Place of "exploratory vitrectomy" in the treatment of retinal detachment without proliferative vitreoretinopathy].

INTRODUCTION: One of the principal causes that may contribute to failure in the treatment of retinal detachment without PVR is the inability to detect the retinal break before and during surgery. We propose in these cases the use of exploratory primary vitrectomy allowing the location and the treatment of the retinal break. MATERIAL AND METHODS: We have studied retrospectively 19 cases of retinal detachment without any preoperatively identified break. In 14 cases, it was a pseudophakic detachment (the IOL was in the posterior chamber with an optic between 5 and 6 mm), in 5 cases it was a phakic detachment. Peripheral fundus was examined with the vitrectomy probes with and without perfluorocarbon liquid injection. Cryotherapy or endophotocoagulations have been used to create a chorio-retinal adhesion and a gaz tamponade was used without scleral buckling procedure. RESULT: In 2 cases, no retinal break was found. In the other cases, the retinal tear has been identified during basal vitrectomy in 8 cases, during injection of perfluorocarbon in 2 cases and during the vitrectomy done forward the PFLC in 7 cases. The retinal break was identified as a small retinal tear along the posterior margin of the vitreous base in 15 cases (several in 2 cases) and as atrophic hole in 2 cases. DISCUSSION: Exploratory vitrectomy is an interesting technique to identify a retinal break when a scleral indentation cannot offer a good visualization of the anterior retina or retinal tears. In young phakic patients, a primary vitrectomy may be dangerous but seems to be justified in pseudophakic eyes. The research of the tear is sometimes facilitated by a peroperative tamponade of the retro equatorial retina.

Aged↗
PubMed1997

[Surgical treatment of serous detachments of the macular neuroepithelium in diabetics].

PURPOSE: Maculopathy in diabetes mellitus represents one of the most serious complications of the diabetic retinopathy. Retinal photocoagulations are often impossible and even dangerous. We propose a new method of surgical treatment for this macular serous detachment. MATERIAL AND METHOD: Thirteen eyes from 11 patients were treated using the same surgical procedure: vitrectomy, aspiration of subretinal liquid through a temporal retinotomy, fragmentation and extraction of the sub and intra retinal exsudates through one or several retinotomies, macular massaging with fluorodecaline, endophotocoagulations (focal on vascular anomalies and macular grid) and fluid-gas exchange (C3F8). RESULTS: Macular serous detachment and subretinal exsudates disappeared in all the cases, the fluorescein leakage decreased. A functional improvement was obtained in 11 eyes, a stabilization in 2. DISCUSSION: The clinical results of this new surgical treatment appear to depend on the preoperative macular ischemia and on the age of the detachment. This surgical procedure is very beneficial but could perhaps be technically improved.

Aged↗
PubMed1992

Primary uveal B immunoblastic lymphoma in a patient with AIDS.

A case of primary intraocular malignant lymphoma without cerebral involvement is reported in a 30-year-old man with acquired immunodeficiency syndrome. The study of the enucleation specimen showed a B immunoblastic lymphoma with a CD30 positive anaplastic large cell component. There was no involvement of the adnexal structures of the orbit. The patient subsequently completed non-surgical staging showing no extension of the tumour. The clinical course was rapidly fatal with dissemination to the pericardium and pleura.

Adult↗
PubMed1989

[Cryosurgery in the treatment of basal cell epithelioma of the eyelids].

Modern cryosurgery, based on impedance measurement, is a valuable addition to excisional surgery and radiation therapy in the management of eyelid malignancies. The advantages of the procedure are the good cosmetic and functional results. For the management of basal cell carcinoma situated near the punctum lacrimale and lacrimal canaliculus, cryosurgery may be preferred to surgery and radiotherapy. We review principles, methods, clinical and histological presentation of cryosurgery and describe our preliminary results.

Aged↗
PubMed1988

[Malignant hyperthermia in ophthalmologic surgery].

Malignant hyperthermia is a potentially fatal complication of general anesthesia that may occur with greater frequency in ptosis and strabismus surgery. The case of a two-year-old girl who suffered a malignant hyperthermia crisis during strabismus surgery is reported. The pathophysiology, clinical features, treatment and pre-anesthetic diagnosis are reviewed in detail.

Anesthesia, General↗
PubMed1981

[Not Available].

Explore the source record for details and available documents.

History, Modern 1601-↗
PubMedDate not supplied

[Retinitis pigmentosa and vitreo-macular traction syndrome. An anatomo-clinical and histopathological study apropos of a case].

PURPOSE: A case of congenital epiretinal membrane associated with retinitis pigmentosa is reported. PATIENT: A 30 year old man with retinitis pigmentosa was operated for a vitreomacular traction syndrome. The epiretinal membrane removed during surgical procedure was analyzed in electronic microscopy. RESULTS: Visual acuity, 6 months after the intervention: improve at 20/400, because of amblyopia. The study in electronic microscopy reveals many fibroblasts in an abundant collagenic tissue without glial cells. DISCUSSION: The observation of such an epiretinal membrane is unusual during retinitis pigmentosa. Its origin is probably congenital and the vitreous may play some role in its evolution. The systematic examination of the vitreoretinal interface represents an important element of the surveillance of retinitis pigmentosa.

Adult↗
PubMedDate not supplied

[Role of growth hormone in proliferative diabetic retinopathy. Clinical and immunohistochemical aspects].

The first part of this work deals with the various therapeutics with pituitary aims on ten patients with proliferative retinopathy. In the second part, the Growth Hormone involvement is considered, by the mean of IGF-I dosages in the serum and the vitreous of diabetic and non-diabetic patients. IGF-I is also sought in neovascular membranes by immunohistological methods. If radioimmunological dosages are negative, IGF-I deposits are found into new vessels wall. The significance of these immunohistological findings remains to be determined.

Adult↗