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Biomedical subjects

F Nogales-Ortiz

Publications and source records attributed to F Nogales-Ortiz.

5 recordsLinked to original sources

The pathology of female genital tuberculosis. A 31-year study of 1436 cases.

The pathology of 1436 cases of female genital tuberculosis (FGTB) observed from 1946 to 1977 is reviewed. The frequency of FGTB was highest in 1956, when it represented 5.5% of all gynecologic pathology specimens. The incidence declined in 1964 as a result of a nationwide antituberculosis campaign, falling to 0.27% in 1977. Sixty-six percent of the patients were 25-35 years of age, and 11% were postmenopausal. All patients presented with either primary (94%) or secondary (6%) infertility. The percentages of involvement of the different parts of the genital tract were: fallopian tubes 100%, endometrium 79%, cervix 24%, vulva and vagina 0.07%, and ovaries 11%. The clinicopathologic and diagnostic criteria of FGTB in the different regions are described, and special attention is paid to the effects of specific treatment on the tuberculous lesion.

Adnexal Diseases↗

The normal menstrual cycle. Chronology and mechanism of endometrial desquamation.

Morphologic studies were performed on 25 uteri obtained at different times during the menstrual cycle, ranging from 2 to 140 hours following the onset of menstruation. The amount of endometrium desquamated varied; usually only the more superficial parts--the compacta layer and small areas of the spongiosa--were shed, but in some instances desquamation extended almost to the muscularis. The remaining spongiosa, depleted and shrunken, is misleading in its appearance, resembling a basalis layer. Actually, such a layer appears morphologically distinct only during the initial parts of the cycle and undergoes secretory changes at the same rate as the rest of the endometrium. Desquamation and regeneration coexist, desquamation appearing almost complete by 60 hours, whereas regenerating epithelium is seen as early as 36 hours. Complete regeneration takes place by 140 hours after the initiation of menstruation.

Endometrium↗