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Biomedical subjects

F Novotný

Publications and source records attributed to F Novotný.

At least 19 recordsLinked to original sources
PubMed2006

First report on Encephalitozoon intestinalis infection of swine in Europe.

Encephalitozoon intestinalis infection of sows is reported from a pig farm in Slovakia. Spores were detected by direct microscopic visualisation in the faeces of 25 out of 27 sows (92.6%). This finding was also supported serologically by the presence of specific anti-E. intestinalis antibodies and by a species-specific polymerase chain reaction (PCR). This is the first report on E. intestinalis infection of swine in Europe.

Animals↗
PubMed2004

[Conversion of an external fixation to that with an intramedullary pin in cases of complicated diaphyseal fractures].

In this study the authors present a method of conversion of external fixations to closed intramedullary ones in the treatment of complicated diaphyseal fractures of the calf and femur. According to the conditions, the fixation is secured by a pin. The above mentioned procedure is advantageous especially in cases of patients with open fractures, in patients with polytraumas as well as in patients with a threatening or with a present compartment syndrome. Treatment of the above fractures is not always simple and represents a serious problem in everyday traumatological practice. Treatment of fractures using the above procedure has very good results with a minimum of complications. Although, nowadays, the skeletal defect can be solved and therefore the bearing capacity of the extremity be renewed, damages to the muscles are often irreparable and cause a permanent invalidity.

Adult↗
PubMed2003

[Indication criteria for surgical treatment of thoracic outlet syndrome].

When formulating indications for surgery of the thoracic outlet syndrome (TOS) the authors use as a basis their own experience with treatment of 42 patients and data from the literature. The basis is the fact that to the great majority of patients at the time after establishment of the diagnosis comprehensive and systematic rehabilitation care was not available either because lack of time or due to the absence of a department within their reach which could ensure adequate care. The authors discuss the reasons why they prefer after accurate establishment of the diagnosis a primary surgical approach and elimination of the cause of further mechanical damage of the neurovascular bundle with necessary and obvious continuation with long-term intensive rehabilitation. This is a reverse procedure than that recommended by some others concerned with this problem.

Adolescent↗
PubMed2003

[Surgical treatment of peritoneal adhesions--personal experience].

Peritoneal adhesions develop virtually in all abdominal operations. In about 30% they cause subsequent complications, especially disorders of intestinal passage, spasms and female infertility. The authors describe their first experience with implantation of resorptive foil Seprafilm and recommend general scheme for the approach in prevention and subsequent solution of the problem of adhesion-lysis.

Adult↗
PubMed1990

[Indications for surgical intervention in acute pancreatitis].

The authors analyze in detail a group of 48 patients treated on account of acute pancreatitis in 1988. As regards the severity and prognosis of the disease, they divide it according to the Mainzer classification into three groups. The first mildest one was not subjected to acute operation. Serious cases in group 2 and 3 called in a total of 22 cases for operation. The authors discuss in detail indications for surgical intervention from four basic aspects: laboratory findings, ultrasonographic and CT examination, the clinical picture and character of the exudate in the abdominal cavity. It is essential to evaluate in a comprehensive way all symptoms and the dynamics of their development, in particular, however, the clinical picture of the disease. The possible lack of of some paraclinical examinations (ultrasonography, CT) must not play a decisive role for the indication.

Acute Disease↗
PubMed1989

Roxithromycin--a new macrolide derivative.

This ether oxim derivative of erythromycin A is an easy to absorb oral antimicrobial somewhat less effective in vitro than erythromycin. At relatively low MIC's it is active against staphylococci, streptococci, pneumococci, branhnamella and chlamydiae, higher concentrations are needed against enterococci and some strains of H. influenzae. Roxithromycin is also reported to have a very good effect on campylobacters, many anaerobic bacteria, Toxoplasma gondii, Treponema pallidum, Mycoplasma pneumoniae and Legionella pneumophilla. Its half-life in the serum of healthy individuals ranges from 9 to 16 hours. Maximum serum concentrations at 2 oral doses of 150 mg a day are reached at 3 to 4 days and vary from 5.5 to 11.1 mg/l. The distribution of roxithromycin in body tissues is excellent. In a group of 57 patients treated for various infections of clear etiology the positive therapeutic effects resulting in the state of bacteriological negativity was reached in 86% of cases. Roxithromycin can be recommended as a drug of choice in mild or less severe cases of infection caused by agents sensitive to this antimicrobial. Its excellent tolerance makes it especially well suited for use in pediatric practice.

Adult↗