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Biomedical subjects

F Nozzoli

Publications and source records attributed to F Nozzoli.

8 recordsLinked to original sources
PubMed1984

Cisplatin and etoposide combination in the treatment of bronchogenic carcinoma.

The authors investigated the activity of a combination of DDP 80 mg/m2 i.v. followed by VP16 50 mg/m2 on days 2-5 in bronchogenic carcinoma. Twenty-seven patients entered the study (10 small cell carcinoma, 9 squamous cell, 2 adenocarcinomas and 6 histologically undefined). Six patients evidenced partial response (22.3%); one patient (small cell) had complete remission. The toxicity of the regimen was scarce and well-tolerated by patients with an incidence of 88.8% alopecia, and 77.7% nausea and/or vomiting.

Adenocarcinoma↗
PubMed1981

[Diagnostic significance of assaying glycoproteins, immunoglobulins, complement fractions and carcinoembryonic antigen in pleural and peritoneal exudates and transudates].

The Authors have determinated the concentration of some glicoproteins, IgG, IgA and IgM, C3 and C4 and CEA in 61 peritoneal and pleuric effusions, of various aethiology. Results obtained for glicoproteins and C3 appear to have a diagnostic value in distinguishing inflammatory and neoplastic effusions from non-inflammatory and non-neoplastic forms. A greater diagnostic value can be attributed to the results of the CEA which is constantly and almost exclusively increased in neoplastic effusions.

Ascitic Fluid↗
PubMedDate not supplied

Serum NSE, CEA, CT, CA 15-3 levels in human lung cancer.

The significance of neuron specific enolase (NSE) was investigated in comparison with other tumor markers (CEA, CT, CA 15-3) used in the diagnosis and treatment monitoring of lung cancer. As previously described, the calcitonin assay proved to have very low sensitivity for small cell lung cancer (SCLC). The serum NSE assay was, however, shown to be a useful diagnostic aid for discrimination between histologically different lung cancers, and therefore this assay may be a valuable tool for treatment monitoring in SCLC patients. CA 15-3, also an unspecific marker, showed similar sensitivity to the NSE assay in SCLC patients, the sensitivity being higher than CEA in non small cell lung cancer (NSCLC).

Adult↗
PubMedDate not supplied

[Comparative analysis between qualitative and quantitative features of orofaringeal and tracheo-bronchial bacterial flora in normal subject (author's transl)].

In 28 subjects surely without tracheo-bronchial phlogosis it had been observed that the trachea and the bronchi are mostly sterile, only rarely there is a normal bacterial flora. In the mouth and in the pharynx there is instead, almost always, normal bacterial flora and only exceptionally potentially pathogenous strains at a concentration inferior to 10(7).

Adolescent↗