Ultrastructural localization of calcium in the rat retina with a combined oxalate-pyroantimonate technique.
Explore the source record for details and available documents.
Animals↗
Biomedical subjects
F Offner
Publications and source records attributed to F Offner.
1-f fluctuation in membrane potential as related to membrane theory.
Explore the source record for details and available documents.
Biophysical Phenomena↗
Change in zeta potential of polar plastics by electrical polarization.
Explore the source record for details and available documents.
Electric Conductivity↗
Development of the contingent negative variation in children.
Explore the source record for details and available documents.
Adolescent↗
A diffusion theory of membrane excitation.
Explore the source record for details and available documents.
Calcium↗
A coincidence technique for fetal electrocardiography.
Explore the source record for details and available documents.
Electrocardiography↗
Extended liver resection and hepatic ischemia in pigs: a new, potentially reversible model to induce acute liver failure and study artificial liver support systems.
BACKGROUND: Extended hepatectomy is a valid model for the study of acute liver failure. Since the porcine liver is comparable in size, morphology and anatomy to the human liver, we describe a technique employing hepatic ischemia and extended liver resection to induce acute liver failure in a porcine model as a means of studying bioartificial liver support. METHOD: A subtotal (75-80% resection) extended left hepatectomy was performed in 7 pigs after 60 min warm ischemia of the future remnant liver. After resection, the animals were given the best supportive care and observed until death. RESULTS: All animals died within 18-48 h, none as a result of surgical complications. Gross appearance of the liver showed severe steatosis of the right lateral lobe, and histology revealed severe coagulative necrosis of the whole lobule. CONCLUSION: This technique of extended liver resection after hepatic ischemia in the porcine model may be useful for studies of potentially reversible acute liver failure and experimental bioartificial support.
Animals↗