PubMed Health⌕ Search

Biomedical subjects

F Olbert

Publications and source records attributed to F Olbert.

At least 37 records · Page 2Linked to original sources

[Intra-arterial infusion treatment in lung neoplasms].

Intraarterial infusionstherapy was performed with cytostatic agents (10 patients) and proteolytic enzymes (4 patients) in 14 selected cases with malignant lung tumours. Diagnosis was in 8 patients small cell carcinoma, in 3 patients adenocarcinoma, in 2 patients squamous cell carcinoma of the lung and in 1 patient leiomyosarcoma of the lung (relapse). Infusions were performed in 8 cases through the A. bronchialis, in 5 through the A. pulmonalis and in 1 patient through the A. thoracica interna. After single infusions of cytostatic agents via the A. bronchialis, remissions of varying extents, were found in 5 out of 8 patients. Repeated infusions with enzymes (1-5 series) through the A. pulmonalis lead in 2 out of 4 cases to slight remissions with a duration of 5 and 12 months, respectively. Possibilities and limiting factors of this therapeutic modality are demonstrated by recent observations.

Adenocarcinoma↗

[Aneurysmal dilatation of the bulb of the azygos vein. Radiological and clinical value].

An aneurysm of the vena azygos should be taken into consideration when establishing the differential diagnosis of a tumor in the area of the right tracheobronchial angle or of an enlargement of the right upper mediastinum. Bilateral pelvic phlebography with demonstration of the retroperitoneal venous system and the azygos venous system is the only purposeful examination. Tentative diagnosis is made on the basis of the X-ray (radioscopy and general X-ray of the chest) and is supplemented by X-rays of the patient in a recumbent position (Valsalva- and Müller-test) and appropriate tomography. The most frequent cause of the azygos aneurysm in our patients was aplasia of the inferior vena cava. One patient presented an infrahepatic interruption of the inferior vena cava with azygos continuation. Phlebography of the inferior vena cava should always be performed in cases of azygos aneurysm. An abnormality of the inferior vena cava may be missing; in such cases the existence of a cardiac defect, abnormal emptying of pulmonary veins or hepatic cirrhosis should be taken into consideration. The enlargement of the azygotic arch may also occur during pregnancy. Thus an azygos aneurysm is frequently but not necessarily associated with enlargement of the azygotic arch. We saw one patient among our cases who presented aplasia of the inferior vena cava without any dilatation of the azygotic arch.

Adolescent↗

Aneurysmal bulb dilation of the azygos vein: radiological and clinical significance.

An aneurysm of the azygos vein is usually detected in the course of routine chest X-rays. It presents as a sharply circumscribed tumor shadow in the area of the right tracheobonchial angle or as an enlargement of the upper right mediastinum. A tentative diagnosis is supplemented both by further X-rays in a supine position in combination with the Valsalva and Müller tests and by tomography. The most frequent cause of an azygos aneurysm found in our material is aplasia of the inferior vena cava. Infrahepatic interruption of the inferior vena cava with azygos continuation can also be an associated malformation. Therefore, bilateral pelvic phlebography with visualization of the retroperitoneal venous and azygos systems is mandatory for establishing the correct, complete diagnosis. We have found no concomitant hemodynamic derangements. It is important to note that under these circumstances no therapy is indicated.

Adolescent↗

Radiological procedures in portal hypertension.

Radiological diagnosis in portal hypertension is of paramount importance for proper treatment. The site of portal obstruction is determined preoperatively by either direct (splenoportography, transumbilical portography, epiploography, selective percutaneous transhepatic catheterization) or direct (catheterization of the celiac truncus and/or the superior mesenteric artery) methods. After a shunt procedure the examination can best be done with a balloon catheter, by direct catheterization of a shunt or by indirect splenoportography. Recently, the radiologist has started to do the treatment by percutaneous transhepatic injection of a sclerosing agent into the gastric coronary vein. For each different method the advantages and disadvantages, the indications and technical procedure are described and discussed.

Adolescent↗

[Surgery of endotheracic struma].

Most cases of endothoracic struma should be considered as systemic illnesses that require thoracic surgery. Concerning cervicoendothoracic borderline cases, the same point of view is advocated, e.g., struma endothoracica falsa and vera alliata. With reference to 38 cases of true and 34 cases of false endothoracic struma, the authors summarize and discuss: 1) their experiences in diagnosis, 2) various routes of access, 3) special thoracic closure techniques, and 4) specific surgical methods on the tumor itself.

Diagnosis, Differential↗

[Successes, failures and complications in thrombolytic therapy in peripheral, arterial and venous occlusions].

Thrombocytic therapy in peripheral arterial and venous vessel occlusion represents a clearly described alternative towards the surgery of vessels. A success rate of 36.5% can be found in subacute peripheral arterial thrombosis and 46.3% in subacute thrombotic occlusion of a bypass-graft. Contrary to that, a rate of 29.8% can be found in complications or side-effects respectively. In cases of peripheral deep venous thrombosis, a partial or full success can be found in 72%. However, the rate of complication amounting to 44.2% is comparatively high. The longer thrombolytic therapy with streptokinase or urokinase will last, the more frequently and more serious will be the complications, such as bleedings of different kind as well as increase of temperature to mention the most frequent ones. The application of urokinase is absolutely possible today, however, the use of urokinase seems to be only justified, if a thrombolytic therapy with streptokinase was carried out successfully and a subsequent surgical therapy was not possible. The present costs of this preparation are far too high for urokinase to be applied routinely. A thrombolytic therapy with SK as well as with UK has to be followed by an anticoagulant treatment.

Arterial Occlusive Diseases↗