Polyamines and virus multiplication.
Explore the source record for details and available documents.
Animals↗
Biomedical subjects
F P McCormick
Publications and source records attributed to F P McCormick.
Polyamine metabolism in cells infected with herpes simplex virus.
Ifection of LS cells with HSV-1 resulted in an inhibition of spermidine and spermine synthesis from putrescine, possibly through inhibition of host cell protein synthesis. The rate of putrescine uptake increased soon after infection, and later, polyamines were lost from the cells. Inhibition of spermidine and spermine synthesis by methylglyoxal bis (amidinohydrazone) did not affect virus replication.
Animals↗