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F PRZESMYCKI

Publications and source records attributed to F PRZESMYCKI.

At least 19 recordsLinked to original sources

Vaccination against poliomyelitis in Poland with types 1 and 3 attenuated viruses of Koprowski. 1. Virological studies of the vaccine strains and serological studies of the vaccinated population.

Mass vaccination of the juvenile population with live poliovirus vaccine was carried out in Poland in 1959 and 1960. In all, some 7 239 000 children 6 months to 14 years old were given type 1 (CHAT) virus, and nearly 6 818 500 children of the same age-group received type 3 (W-Fox) virus.A serological conversion rate (from <1:4 to >/=1:4) of 91.7% was achieved with type 1 and of 91.0% with type 3-a satisfactory demonstration of the immunogenicity of the strains used. Although type 2 virus was not administered, seroconversion with this type occurred in 65.4%. This may have been caused by antigenic elements common to the three poliovirus types, and previous vaccination with Salk vaccine may also have been a contributory factor.The authors conclude that the mass vaccination described in this paper has created a highly immune population in Poland.

Adolescent↗

The epidemic of Asian influenza in Poland, 1957.

In 1957 the number of influenza cases began to rise above the inter-epidemic level in the 32nd week of the year in Katowice Province of Poland and in the 41st week in the majority of remaining provinces. The peak was reached between the 42nd and 45th weeks in the various provinces, in which the total epidemic lasted for periods varying from eight to 11 weeks. For the country as a whole, the main epidemic period was October-November.The clinical picture was generally rather mild, with very few serious cerebral symptoms and no complications of the peripheral nervous system. The epidemic appears to have caused no increase in the number of deaths from pneumonia in infants, but there was a slight increase among children of school age and a marked one among adults, for whom the figures for complications of all sorts were rather higher than in the previous influenza epidemics.Serological tests on paired human sera showed a marked increase in complement-fixing antibody in several. Haemagglutination-inhibition tests were carried out on both human and animal sera, negative results being obtained in almost all the latter. Nine influenza strains were isolated, identified as Asian influenza. Two of them showed a low avidity to the Singapore and other Asian immune sera.

Adult↗

Epidemiology of influenza in Poland, 1947/57.

Two systems of influenza reporting in use in Poland are described; one involves weekly reports by the public health laboratories, the other quarterly reports on influenza absenteeism. A third, experimental, system of daily reports is used in Łódź. Data obtained by all three systems are compared in this assessment of influenza epidemiology in Poland. Study of the epidemics of the last decade leads the authors to the conclusion that a number of them were possibly caused by a local virus which had earlier "taken root" in the country rather than by a virus imported from neighbouring countries. Attention is drawn to the isolation in 1953 of a strain related to PR8, generally held to be no longer circulating by that date. For reasons given, it is thought unlikely that this isolation was due to a laboratory accident.

Epidemics↗

Vaccination against influenza in Poland, 1953/56.

The authors describe the methods, organization and results of four large-scale trials of polyvalent, intranasal influenza vaccine conducted in Poland between 1953 and 1957. Vaccination was carried out mainly in industrial establishments, workers' and students' hostels and schools. Very few post-vaccination reactions were seen.In these trials, the formalinized intranasal vaccine, which has the advantage of being easy to administer, gave results not greatly different from those obtained in other countries with injected vaccines or with intranasal live-virus vaccine. The inclusion in the vaccine of a large number of strains, thus giving a broad antigenic spectrum, made it possible to obviate the difficulties involved in isolating a "precursor" strain, and thus made for quicker and more abundant vaccine production before an epidemic.

Administration, Intranasal↗