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Biomedical subjects

F Pancrazio

Publications and source records attributed to F Pancrazio.

At least 19 recordsLinked to original sources

[Thyroid metastasis due to right colonic carcinoma].

Clinical evident metastases to the thyroid gland are rarely found antemortem. A case of a 62 year-old man with a history of right colonic carcinoma, who presented a mass in the right lobe of his thyroid gland one year after the removal of a metachronous metastasis in his right lung, is presented. The tumour of the thyroid was found to be metastatic adenocarcinoma from his previous colonic cancer. The clinical finding of metastases to the thyroid gland is rare, particularly from a colorectal primary neoplasm. However, the possibility of a tumour of the thyroid gland representing a secondary malignancy is to be considered in any patient with a prior history of cancer.

English Abstract↗

[Dacron-EXS prosthesis in axillo-femoral bypass].

Twenty-eight axillary by-pass were performed in 27 patients using a dacron externally supported prosthesis. This group of patients has been compared with two other groups in which a dacron knitted (20 p.) or a PTFE (55 p.) prosthesis were implanted. A three years patency has been respectively: 66.6% (EXS), 57.7 (PTFE), 45.5 (Knitted Velour).

Aged↗

[Complications of vascular prosthesis].

The main complications deriving from the use of vascular prostheses in the surgical reconstruction of the arteries are thrombosis, infection and the appearance of pseudoaneurysms. Among 233 aorto-femoral b.p., prosthetic thrombosis occurred in 45 patients creating the need for 66 reoperations, 19 early and 47 tardive. In 387 aorto-iliac reconstructions, infection arose early in 11 cases, tardively in 6. Out of 1118 vascular reconstructions there were also 28 pseudoaneurysms (2.5%). After remarks on the aetiopathogenesis of such complications, methods that can be used to prevent them are discussed and personal results of treatment are presented.

Aneurysm↗

Telethermography and axillary node status as predictors of early relapse in breast cancer: preliminary report.

The authors report on 141 primary, non-metastatic, breast cancer patients with a minimum follow-up of 12 months after surgery to a maximum of 5 years. All cases were studied according to the patterns of the preoperative telethermography (TH) and nodal status (N). Prognosis was evaluated in terms of incidence of relapse. A statistically significant correlation was found between TH+ and early relapse, and for N+, but there was no correlation between TH and N, both for negative and positive values. The results suggest a complementary prognostic value of the two parameters.

Breast Neoplasms↗

Theoretical and practical aspects of receptor hormone assay in breast cancer.

The Authors have discussed the importance of ER/PR assay in breast cancer care. 162 patients were studied. The dextran-coated charcoal technique was used as the standard most readily available. The Authors point out the importance of specimen handling as is shown by time-decay studies, and the differences in ER/PR level at the time of the biopsy and mastectomy cut-section, and its eventual influence to better understanding assay results. The establishment of a center of control between different labs would also help in the development of more exact regimens for cancer care.

Breast Neoplasms↗

[Testicular atrophy and gonadotropin activity in rats with portacaval anastomosis].

Rats subjected to porto-caval shunt present, even after a rather long period since the operation (5 months), a moderate atrophy of the testicles. This phenomenon occurs because of a reduced gonadotropic activity of the pituitary gland, consequent upon a more or less increased inhibition of the hypothalamic GTH-RF production. The abnormal depression of the hypothalamic activity is due to a scarce metabolism of the sexual hormones following the operation.

Animals↗

[Use of laminar flow apparatus in vascular surgery].

Post-operative infection is one of the main risks attached to surgery, especially when synthetic materials or artificial prostheses are employed. The fundamental principles of laminar flow apparatuses are described, with particular reference to one employing a horizontal flow and fluid bulkheads. During the first two years of its use, this particular apparatus has reduced cases of infection from prostheses in vascular surgery from 5.5 to 1.8%.

Air Conditioning↗

Axillo-femoral by-pass: technique and long-term results.

The paper describes problems related to axillo-femoral (AF) revascularization of the lower limbs on the basis of personal experience of axillo-femoral by-passes performed from 1971 to 1987. The indications to this technique are limited to high-risk patients. The long-term results are analyzed. The paper stresses the difficulties connected with the choice of the level of the proximal and distal anastomoses, as well as the type of prosthesis to be used.

Anastomosis, Surgical↗

Acute thrombosis of the infrarenal aorta. Therapeutic problems.

Acute thrombosis of the infrarenal aorta is a rare event, usually complicating aortic atherosclerotic lesions or aortic aneurysms. During the last twelve years, we treated 10 acute aortic thromboses out of 353 acute ischemias of the lower limbs (2.8%). The high mortality of our series (60%) is related to advanced age (71 years on average), severe underlying cardiopathy, and the frequent involvement of the renal and mesenteric vessels. In our experience Fogarty catheter thrombectomy is usually ineffective, and the surgical approach in high risk patients should be confined to axillobifemoral bypass graft.

Acute Disease↗

Long term results of extra anatomical bypasses.

The authors discuss their own experience with extra anatomical bypasses. It is composed by 214 patients who underwent 224 extra anatomical bypasses: 167 axillofemoral bypasses, 50 femorofemoral bypasses and 7 trans-obturator bypasses. The indications included the presence of infections, or a previously thrombosed aortic prosthesis, or infected aneurysm, in 12.1% of the cases; in 6.2% of the cases the extra anatomical bypass was due to acute ischaemia of limb. In 81.7% it was chosen because of the presence of some general or local contraindication to direct aortoiliac reconstruction. The results are comparable to those reported in the literature. The only unusually high datum is the rate of early infections in femorofemoral bypasses (12%). On the ground of these results, the Authors stress the value of extra-anatomical bypasses as an alternative to direct aortoiliac reconstructions.

Aged↗