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PubMed1995

An 'ethics gap' in writing about bioethics: a quantitative comparison of the medical and the surgical literature.

In order to determine whether there is a significant difference between the medical literature and the surgical literature in terms of their bioethics content, we conducted a computerized search of the MEDLINE database. The journals searched were selected from the 'Medicine' and 'Surgery' sections of the 'Brandon-Hill List', and the search was limited to 1992 issues of these journals. Three hundred and seven bioethics bibliographic records (out of a total of 11,239 articles indexed) were retrieved from the 15 medical journals searched, while 17 bioethics bibliographic records (out of a total of 2,645 articles indexed) were retrieved from the 12 surgical journals searched. We conclude that there is a statistically significant (p < 0.001) difference between the medical literature and the surgical literature with respect to their quantitative bioethics content.

Bibliometrics↗

PubMed1989

Cholesterol and cancer: comparative biochemistry and selective toxicity.

There is abundant evidence in the literature for the existence of a difference between normal and neoplastic cells with regard to the regulation of cholesterol biosynthesis. More specifically, the loss of negative feedback control of this pathway seems to be a property of transformed cells. Herein we describe the relationship between cholesterol and cancer, and we describe a model which attempts to employ Adrien Albert's second principle of selectivity--that of comparative biochemistry--by exploiting the above mentioned difference in regulation.

Animals↗

PubMedDate not supplied

Changing one's mind.

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Decision Making↗