Biomedical subjects

F Papadellis

Publications and source records attributed to F Papadellis.

4 recordsLinked to original sources

PubMed1985

Statistical aspects of hydatid disease in Greek adults.

A retrospective study was undertaken to estimate the incidence of hydatidosis among Greeks over 18 years of age. Discharge and operating room records in all community and private hospitals during the period 1 January 1969 to 31 December 1975 were reviewed, and new hydatid patients were registered. Hydatid disease was diagnosed in 4,202 adults. The average annual incidence of all hospital cases was 9.77 per 100,000 population. The diagnosis was confirmed at surgery in 3,397 patients (80.84%). The average annual surgical incidence was 7.89 per 100,000 inhabitants. The incidence of the disease varied among different geographic areas in the country; its percentage was highest in rural areas. In this series, both sexes were equally involved (P greater than 0.1). Solitary organ involvement occurred in 95.88% of cases. Cysts were localized in the liver in 69.64% and in the lungs of 23.43% of the cases with single organ involvement. Liver involvement was more frequent in women, while lung involvement was more frequent in men (P less than 0.001).

Adult↗

PubMed1983

Hydatid disease in Greek children.

The surgical incidence of hydatidosis in the Greek population aged 0-18 years was investigated. Discharge and operating room records from 1 January 1969 through 31 December 1975 in all hospitals of the country were reviewed. Data were statistically analyzed according to geographical and annual distribution of the disease, age, sex, and organ affected. Of a total of 4,566 patients with hydatidosis, 534 (11.7%) were 0-18 years old. By extrapolation, operations in this age group were performed at a rate of 2.7/100,000 population per year. Surgical incidence of hydatidosis varies among different geographical areas in Greece; its percentage is highest in rural areas. The disease is more frequent in boys than in girls (P less than 0.01). Lungs and liver are the most commonly involved organs (94.2%). Lung involvement is more frequent in boys (73.0%) than in girls (50.5%) (P less than 0.001).

Adolescent↗

PubMed1979

Electrolyte abnormalities in lymphosarcoma after chemotherapy.

A 12-year-old female with lymphosarcoma responding to treatment including vincristine and cyclophosphamide developed clinical and laboratory findings compatible with the syndrome of inappropriate secretion of antidiuretic hormone. Some additional findings were observed, i.e. uremia, hypopotassemia and alkalosis, that have not so far been recorded in that syndrome. All abnormalities were corrected upon water restriction. A similar episode occurred after a 2nd drug course. It too was corrected upon water restriction. The patient was clinically free from her malignancy in both episodes. It is suggested that our child had probably an expanded form of the syndrome of inappropriate secretion of antidiuretic hormone.

Child↗

PubMedDate not supplied

Glomerular microproteinuria in children treated with non-steroidal anti-inflammatory drugs for juvenile chronic arthritis.

The urinary excretion of selected glomerular (albumin, transferrin, and IgG) and tubular (alpha 1-microglobulin) protein and enzyme (N-acetyl-beta-D-glucosaminidase) markers was studied in 36 patients with juvenile chronic arthritis in order to investigate whether children receiving therapeutical doses of non steroidal antiinflammatory drugs (NSAIDs) and without clinical signs of gross renal dysfunction provide evidence of sub-clinical renal injury. Forty-seven age-matched healthy children as well as nine children with juvenile chronic arthritis but without NSAID therapy served as control groups. Although there was no difference between patients and controls regarding the serum creatinine and urea nitrogen levels, the urinary excretion of all three glomerular markers was significantly elevated in the patient group treated with NSAIDs (p < 0.001). In contrast, there was no difference between patients and controls concerning the urinary excretion of both tubular markers. Furthermore, no correlation was found between protein and enzyme excretion and the onset type, duration or activity of the underlying disease. Taken together, these data indicate that patients receiving NSAIDs display signs of glomerular dysfunction concerning the handling of plasma proteins. The systematic assessment of urinary protein- and/or enzyme-excretion may constitute a useful tool for the early detection and monitoring of otherwise subclinical renal injury in patients treated with NSAIDs.

Acetylglucosaminidase↗