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Biomedical subjects

F Partono

Publications and source records attributed to F Partono.

At least 55 records · Page 3Linked to original sources
PubMed1977

Brugia malayi in seven villages in South Kalimantan, Indonesia.

Seven villages in South Kalimantan were visited in 1971 and night peripheral blood smears from 2,764 people examined for microfilariae. Brugia malayi was found endemic in all villages with microfilarial rates of 12--46% (average 25%) and the median microfilarial density (MfD50) of 6 to 15 microfilariae per 20 microliter of blood. The microfilariae showed a typical subperiodic pattern. The disease was more common in males than females and the prevalence increased with age. Clinical manifestations of filariasis were found in 20% of 1,099 persons examined. Mansonia species are considered important vectors and cats important reservoir hosts. In addition to B. malayi, Dirofilaria repens and an unknown microfilaria were found in cats in the area and strains of the B. malayi and D. repens have been established in the laboratory.

Adolescent↗
PubMed1977

Malayan filariasis in Central Sulawesi (Celebes), Indonesia.

Seven villages in Central Sulawesi were surveyed in September 1971 and finger blood samples from 3,658 persons examined for microfilariae. Periodic, nocturnal Brugia malayi was endemic in all seven villages with microfilarial rates (Mf-rate) of 10-42% (av. 25%). The median microfilarial density (MfD50) averaged 5.4 and varied from 0.8 to 9.4 microfilariae per 20 microliter of blood. Males had higher Mf-rate and MfD50 value than females and in males Mf-rates and MfD50 values increased with age. In the female population, however, neither Mf-rates or MfD50 values varied significantly with age. Clinical manifestations of filariasis were found in 12% of 2,412 persons examined and only 2% had elephantiasis. Clinical signs of disease with the exception of elephantiasis, showed good correlations with Mf-rates but not with MfD50 values. Transmigrants experienced clinical manifestations of filariasis earlier and more often than the indigenous population.

Adolescent↗
PubMed1977

Brugia timori sp. n. (nematoda: filarioidea) from Flores Island, Indonesia.

Brugia timori sp. n. from experimentally-infected Mongolian jirds (Meriones unguiculatus) is described. The adult male differs from other Brugia species, except Brugia malayi, in having a spicular ratio of 3 : 1; it differs from B. malayi in having greater numbers of subventral adanal papillae (up to 5 on each side) that are loosely spaced and irregularly positioned about the cloaca, a greater diameter of the capitulum of the left spicule, greater lengths of the proximal- and midsections of the left spicule, and a greater length of the proximal section of the right spicule. The adult female has an ovejector of greater length and width than that of B. malayi. Microfilariae in the blood of persons from whom the parasite lines of this study originated were typical of the Timor type, having a greater total body length than other Brugia spp., a length to width cephalic space ratio of about 3 : 1, and a sheath which did not stain when processed in the usual manner with Giemsa.

Animals↗
PubMed1977

Brugia timori: experimental infection in some laboratory animals.

Experimental infection with Brugia timori of 7 jirds (Merionesunguiculatus), 4 cats and 2 monkeys (Macaca fascicularis) is described. Although no microfilariae were detected by examining 20 microliter samples of tail blood of jirds, adult worms were recovered from 6 of the 7 jirds at autopsy 69-141 days following infection. Some worms were gravid and microfilariae were found in visceral blood of 2 animals. The adult recovery rate in jirds was 16%; the male to female ratio was 1:3. In cats patent infection developed in 95-105 days but microfilaraemias were of low level and transient. No parasites were recovered from monkeys.

Animals↗
PubMed1976

Timor filariasis: epidemiologic and clinical features in a defined community.

The epidemiology of Timor filariasis was observed during a clinical and parasitologic survey of persons living in a remote village on the island of Flores, Southeast Indonesia. Infection and disease was distributed evenly throughout the community, which was in accord with the breeding and feeding habits of the only identified vector, Anopheles barbirostris. Although micfofilaremia rates appeared independent of host variables of age and sexes and sex, symptoms of disease were greater among males than females, and in both sexes disease rates more than doubled between the first and second decades of life. Symptoms included recurring episodes of inguinal and femoral lymphadenitis with retrograde lymphangitis and fever, abscesses of lymph glands or vessels along the path of the great sapheneous vein and its mae highest yet reported for the Timor filaria; it is a virulent parasite causing serious ill-health among the inhabitants of eastern Flores.

Adolescent↗
PubMed1976

Development of the Timor filaria in Aedes togoi: preliminary observations.

Developmental stages of the Timor filaria recovered from experimentally infected Aedes togoi mosquitoes are described. Mosquitoes were dissected and examined for larvae beginning 1 1/2 days and continuing daily for 9 days after they had fed on a carrier on the island of Flores, Indonesia. Timor microfilariae develop rapidly to third-stage larvae within the thoracic muscles of A. togoi: the first molt occurs at 3 1/2 days, the second molt as early as 5 1/2 days, and infective forms are found at 6 1/2 to 7 1/2 days postfeeding. These larvae were compared with similar stages of subperiodic Brugia malayi recovered from A. togoi fed on an infected jird (Meriones unguiculatus) and the features distinguishing larvae of the Timor filaria from those of B. malayi are restricted to the tails of the first-stage forms. The terminal and subterminal nuclei of the Timor larva are generally smaller than those of B. malayi, and there is little if any bulge of the cuticle around them. A constriction of the tail between these nuclei is subtle or absent. The findings of this study support the view that the Timor filaria is a member of the Brugia complex.

Aedes↗
PubMed1976

Parasitic infections in humans in West Kalimantan (Borneo), Indonesia.

A survey was carried out among inhabitants of eight villages in West Kalimantan Province (Borneo), whereby blood smears were examined for malaria, stools examined for intestinal parasites and sera tested by the indirect hemagglutination test for antibodies to Entamoeba histolytica and toxoplasma gondii. The prevalence of malaria among 3017 people examined was 5.6% (Plasmodium vivax 2.8%, Plasmodium falciparum 2.8%). Brugia malayi microfilariae were found in 3.6% and Wuchereria bancrofti in 0.3%. Ninety-seven percent of 2101 stool specimens examined contained evidence of intestinal parasites. Trichuris trichiura (90%) was most common followed by Ascaris lumbricoides (76%), hookworm, (60%), Etamoeba coli (23%), Entamoeba histolytica (6%), Endolimax nana (6%), Iodamoeba butschlii (4%), Giardia lamblia (3%), Chilomastix mesnili (1%) and Strongyloides stercoralis (1%). Other parasites found were Entamoeba hartmanni, Trichomonas hominis, Balantidium coli, Enterobius vermicularis, Hymenolepis nana, Echinostoma sp. and Physalopterid, Dicrocoeliid, and Heterophyid type-eggs. The amoeba prevalence rate was 30%. Indirect hemagglutination antibody titers equal to or greater than 1:128 for Entamoeba histolytica and 1:256 for Toxoplasma gondii were detected in 7% and 3%, respectively, of 1511 sera tested.

Adolescent↗
PubMed1976

Congenital toxoplasmosis in Indonesia.

An 18-month-old male Indonesian with blindness, microphthalmia and bilateral cataracts was found to have antibody titers against Toxoplasma gondii of 1:512, 1:1024 and 1:1024 respectively by the indirect hemagglutination, indirect fluorescent antibody and Sabin-Feldman dye test. Serum from the child's mother by the same test also demonstrated antibody titers of 1:1024, 1:512 and 1:512 respectively. The clinical manifestations in the child and the presence of anti-toxoplasma antibodies in both mother and child suggest that the disease was congenitally acquired.

Adult↗
PubMed1976

Parasitology survey in northern Sumatra, Indonesia.

A parasitology survey was conducted in five villages in North Sumatra, Indonesia. A total of 3,207 blood smears, 2,066 stool specimens and 969 sera were examined. Sixty (1.9%) inhabitants had malaria (Plasmodium vivax 41, P. falciparum 19), and 20 had Brugia malayi microfilaraemia. The most common intestinal helminths were Trichuris trichiura (87%), Ascaris lumbricoides (75%) and hookworm (58%). Other helminths found in low numbers were Enterobius vermicularis, Strongyloides stercoralis, Taenia sp., Fasciolid, Dicrocoeliid and Echinostoma sp. eggs. Entamoeba coli (25%) was the most common intestinal protozoa followed by Endolimax nana (8%), Entamoeba histolytica (7%), Giardia lamblia (6%), Iodamoeba bütschlii (5%), Entamoeba hartmanni (1%) and Chilomastix mesnili (1%). The amoeba prevalence rate was 31 per cent. Testing of sera for Entamoeba histolytica and Toxoplasma gondii antibodies by the indirect haemagglutination test demonstrated positive reactors in 13 per cent and nine per cent of the population respectively. The greatest number of seropositives for Toxoplasma gondii was at elevations of sea level to five meters and the lowest number at elevations of 5OO-1,000 meters.

Adolescent↗
PubMed1975

Studies on filariasis in the Pacific. 4. The application of the membrane filter concentration technique to a survey of Wuchereria bancrofti filariasis in Kepu district, Jakarta, Indonesia.

A blood survey for filariasis was carried out in the Kepu District of Jakarta. Examination of stained 20 c.mm finger-prick blood thick films and membrane filter concentration (MFC) of 1 ml venous blood. The youngest age group examined, 5-9 years old revealed a mf rate of 17% of which 71% were of a low density character detected by MFC only. The mf rate appears to remain relatively constant from the 10-14 year old group onward, approximately 35%, but at all age groups at least half the infections were of low density. The highest mf rate and density was observed present in the 15-20 year old group.

Adolescent↗
PubMed1975

Toxoplasma antibodies in Indonesian and Chinese medical students in Jakarta.

The presence of antibodies to Toxoplasma gondii in medical students of Indonesian and Chinese ancestry was determined by the indirect hemagglutination test with titers of 1:256 or greater considered positive. The sera from 90 Indonesian and 203 Chinese male (146) and female (147) students between 20 and 30 years of age were tested and positive titers detected in the sera of 16 (18%) Indonesians and 14 (7%) of the Chinese. There were no difference between the presence of positive titer and between males and females of either ethnic groups. Both groups denied eating raw or partly cooked meats and no correlation could be found between the ownership of domestic cats, the eating of exotic meats and positive titers.

Adult↗
PubMed1975

Parasitology survey and seroepidemiology of amoebiasis in South Kalimantan (Borneo), Indonesia.

A parasitology surevy was conducted among inhabitants of 7 villages in 3 regencies in South Kalimantan Province, Indonesia. A total of 2,169 stool specimens, 2,756 blood smears and 1,027 serum specimens were obtained, representing samples from approximately 10%, 12% and 5% of the population, respectively. One to 8 different intestinal parasitic infections were detected in 97% of the people. Those parasites most frequently found were Trichuris trichiura (83%), Ascaris lumbricoides (79%), and hookworm (65%), followed by Entamoeba coli (37%), Endolimaxnana (12%), Entamoeba histolytica (12%), Iodamoeba bütschlii (11%), Giardia lamblia (5%), Entamoeba hartmanni (2%), Chilomastix mesnili (2%). Other parasites found were Enterobius vermicularis, Strongyloides stercoralis, Capillaria sp., Echinostoma sp., Hymenolepis diminuta, and Trichomonas hominis. Giardia lamblia was found more often in younger people and Entamoeba coli, Iodamoeba bütschlii and hookworm in the older age group. Ascaris lumbricoides occurred more frequently in females, and hookworm in males. Plasmodium vivax and Plasmodium falciparum were found in the blood smears of 4.4% of the people, mostly in the younger age groups. Seroepidemiological studies on amoebiasis were done by use of the indirect hemagglutination test with antigens prepared from the HK9 strain of Entamoeba histolytica maintained in axenic cultures. The frequency distribution of the reciprocal antibody titers showed a bimodal distribution with 34% of the population demonstrating positive reactions at titers of 1:128 or greater.

Adolescent↗
PubMed1975

Parasitology survey in the Palu Valley, central Sulawesi (Celebes), Indonesia.

A survey was undertaken in the Palu Valley, Central Sulasesi to determine whether schisto somiasis japonica was endemic in the area and to determine the prevalences rates of intestinal and blood parasites. Seven villages along the Palu River drainage system with an estimated popualtion of 18,700 were surveyed and 2,433 stools, 3,651 blood smears and 1,167 sera were collected and examined.

Adolescent↗