PubMed Health⌕ Search

Biomedical subjects

F Pascasio

Publications and source records attributed to F Pascasio.

14 recordsLinked to original sources
PubMed1984

A multicenter clinical study of cefoperazone.

Thirty-five adult and 11 pediatric patients in nine Philippine hospitals were treated with cefoperazone for various moderate to severe infections. Adults received 1 to 8 gm/day and children received 0.450 to 4 gm/day in two divided doses, for a mean period of eight to nine days (ranges, 5 to 11 days for children and 5 to 30 days for adults). The efficacy rate (cured and improved) was 90.90% for pediatric patients and 85.72% for adult patients. In a group of patients shifted from other antibiotic regimens, efficacy rates were 100% for pediatric patients and 85% for adult patients treated with cefoperazone. No follow-up cultures were obtained from patients from whom 26 pathogens were isolated, but correlations between the isolates and clinical efficacy showed that cefoperazone had an efficacy rate of 92.3%.

Adolescent↗
PubMed1966

Hemoglobins in sheep: multiple differences in amino acid sequences of three beta-chains and possible origins.

Among the three adult sheep hemoglobins (A, B, and C), two (A and B) are reportedly products of alleles. The beta-chains of A and B differ by at least seven scattered amino acid residues whereas the beta-sequence of C differs from A by at least 16 residues and from B by at least 21 residues. These changes suggest that the origin of C-beta antedated the divergence of A and B. Five shared differences between A-beta and C-beta with respect to B-beta can be interpreted as the result of selective advantage in favor of B. A complex of additional mechanisms has possibly been involved in maintaining the A-B- C porymorphism.

Amino Acid Sequence↗