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Biomedical subjects

F Pedersen

Publications and source records attributed to F Pedersen.

At least 73 records · Page 4Linked to original sources
PubMed1979

Effect of alprenolol on mortality among patients with definite or suspected acute myocardial infarction. Preliminary results.

A double-blind study of alprenolol versus placebo was done in patients with definite or suspected myocardial infarction to show the effect of the drug on mortality-rate after a year of treatment in patients aged less than or equal to 65 and to study the tolerance of the drug by patients greater than 65 years of age. The dose given was 5--10 mg intravenously, followed by 200 mg twice a day, orally. Patients in whom beta-blockade was contraindicated were excluded. All deaths, side-effects, and dropouts were recorded. Of the 480 patients in the study, 238 patients received alprenolol and 242 placebo. During the year of follow-up 108 patients dropped out from the study. Mortality was not reduced in patients greater than 65 years of age. In those less than or equal to 65 years alprenolol significantly reduced mortality-rate (20% mortality in placebo group vs 9% in treated group). There was also a significant reduction in mortality-rate among those with definite infarction (28% in the placebo vs 15% in the treated group).

Acute Disease↗
PubMed1976

On acid-base problems in REDY dialysis.

The acid-base status of dialysate and blood during REDY dialysis has been studied. A very low pH (6,90) has been found in the venous blood. However, the predialytic acidosis of the patients is corrected, which is attributed to the acetate supply during dialysis. It is pointed out that the implications of the low venous blood pH are still inadequately investigated.

Acetates↗