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F Piard

Publications and source records attributed to F Piard.

At least 55 records · Page 3Linked to original sources

[A case of liver angiosarcoma arising in a pre-existing cavernous hemangioma].

A 36-year-old woman presented with a solitary hepatic tumor. Macroscopically, the tumor measured 9 cm in greatest diameter, and was well encapsulated; it was reddish, and showed multiple foci of hemorrhage. Microscopic examination revealed two different patterns: a peripheral angiosarcoma surrounding a centrally located cavernous haemangioma. To our knowledge, such an entity has not been reported up to now. Possible pathomechanisms, radiological and pathological findings of this angiosarcoma of liver arising within a cavernous haemangioma are commented.

Adult↗

[Treatment and prognosis of stomach cancers in the population of the Cote d'Or's District (1976-1985)].

The present study on treatment and prognosis of gastric cancers is based on the data of the digestive tract cancer registry set up for the French department of Côte-d'Or. During the 1976-1985 period, 784 cases of gastric cancer were diagnosed. Resection for cure was performed in 41.3% of gastric cancers and that proportion remained the same during the course of the study period. Operative mortality was 18.5% after resection for cure and 26.7% after palliative surgery. The overall survival rate was 31.7% at 1 year, 17.0% at 3 years, and 13.0% at 5 years. Ten different criteria (personal data, histologic and therapeutic parameters) were studied in relation to survival. With the univariate analysis, the survival rates were related to age, duration of the symptoms, history of previous gastric ulcer, tumour location, stage of diagnosis and treatment. Only 4 aspects were of good prognosis according to the multivariate analysis (Cox model): extension limited to the gastric wall, resection for cure, duration of the symptoms and location to the antrum or the angulus. These results underline the fact that the prognosis of gastric cancer in a well-defined population remains poor. Because of its severity, gastric cancer still represents a major cancer problem.

Aged↗

[Favorable outcome of Wegener's disease limited to the lungs. Apropos of a case].

A case of Wegener's granuloma limited to the lungs is reported in a 22 year old man. The pulmonary radiograph showed bilateral nodules. A lung biopsy of a nodule revealed a necrosing vasculitis involving the arteries and the veins and some areas of necrosis in geographical contours around these vessels. The renal function was normal and 4 1/2 years later the outcome remains favourable with the minimum of treatment, the exception being a course of antibiotics post operatively. Fifty seven cases of Wegener's granuloma limited to the lungs have been diagnosed after lung biopsy, transbronchial or bronchial material. The outcome was favourable in 72% of cases. This result was observed in the absence of any treatment in 6 cases (13%). In 2 cases the pulmonary nodules disappeared or developed cavities. In 4 cases the anatomical and/or radiological progress is unknown. Currently the factors leading to such an outcome have not yet been identified.

Adult↗

Bronchiolitis obliterans organising pneumonia in patients taking acebutolol or amiodarone.

Two patients, treated with acebutolol and amiodarone respectively, developed a disease clinically, radiologically, and pathologically indistinguishable from bronchiolitis obliterans organising pneumonia. In one case recovery followed discontinuation of acebutolol; in the other case cessation of amiodarone had no effect, and corticosteroids were required. In addition to these patients, several cases of bronchiolitis obliterans organising pneumonia have been reported during treatment with gold salts, amiodarone, and miscellaneous other drugs. Taken together, this information supports the view that bronchiolitis obliterans organising pneumonia may be a form of response by the lungs to insult by drugs.

Acebutolol↗

[Glandulo-cystic polyps of the stomach. Apropos of 12 cases and review of the literature].

We report 12 cases of cystic glandular fundic polyps detected in 7 women and 5 men. As in the 238 similar previously reported cases these lesions were always located in the fundic gastric mucosae and did not involve the muscularis mucosae. They were discovered by endoscopy in patients with minor abdominal discomfort. They were less than 5 mm in diameter and were more often multiple and sessile; only a few of them were pedunculate. They consisted of mucosal cysts lined with cuboidal, parietal or chief cells and surrounded with a normal lamina propria. If in 213 cases, these polyps were not associated with polyposis coli in 37 cases they occurred with a Gardner's syndrome or a familial adenomatosis coli. These benign lesions are without malignant potential. Careful gastroscopic follow up with biopsy is recommended for all patients with multiple gastric polyps. The etio-pathogenesis of these polyps is still unknown. Their relationship to familial polyposis coli or to Gardner's syndrome is obscure.

Adenomatous Polyposis Coli↗

[Does Ming's classification of gastric carcinomas have epidemiologic or prognostic value?].

The population based registry of digestive tract tumours of the country of Cote-d'Or was used to assess the epidemiological and prognostic value of Ming classification. The 211 gastric carcinomas operated or autopsied between 1976 and 1981 in this population were reviewed on a pathological basis. The expansive type (46.0%) was nearly as frequent as the infiltrative type (47.9%). In 6.2% of the cases it was impossible to classify carcinomas in one of these two types. The male/female ratio was higher in the expansive type (3.0) than in the infiltrative type (2.2) and the mean age of patients at the time of diagnosis was higher in the expansive type (69.5 years) than in the infiltrate type (66.4 years p less than 0,05). Ming classification was difficult to use with superficial carcinomas: 9 out of 12 could not be classified. Among invasive cancers only 1.5% were not classified in one of the two types. Polypoid and fungating carcinomas were more often of the expansive type (70.1%). On the contrary infiltrative carcinomas (ulcerated or not) corresponded to the infiltrative type of Ming in 65.6%. It was not possible to extrapolate the WHO classification to the Ming classification. Infiltrative carcinomas were more often associated with hyperplastic stroma (38.1%) than did expansive carcinomas (5.2%) the proportion of carcinomas limited to the digestive wall was higher in the expansive type (21.7%) than in the infiltrative type (5.0%). The survival rate was better in the expansive type (41.4%) than in the infiltrative type (30.1%) but the difference was not significant. The prognosis depended partly on the time of diagnosis. The results suggest that Ming classification has an epidemiological interest. It allows us to distinguish two types of carcinomas that appear quite different on basis of their growth and penetration capacity. However its prognostic interest appears limited.

Adult↗

[Malignant fibrous histiocytoma of the mesentery. Echographic and x-ray computed tomographic aspects. Apropos of a case].

We report one case of mesenteric malignant fibrous histiocytoma, demonstrated by pain, abdominal mass and hypoglycaemic faintness. Ultrasound showed an heterogeneous mass, with liquid areas surrounded with echogenic trabeculations. A percutaneous aspiration under ultrasound guidance of the liquid collections demonstrated sero-sanguineous material. A computed tomography showed the mass to involve the upper small bowel mesentery; organic hypoglycaemic series suggested a mesenchymal tumor, the histologic type of which was only known by post-mortem examination of the specimen.

Aged↗

[Accessory salivary tissue and deceptive ectopia].

Histopathologic diagnosis in three patients presenting with a cervicofacial salivary tumoral mass was respectively an inflamed accessory salivary glands, two small islets of ectopic salivary glands and an ectopic salivary duct.

Adult↗