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F Picchio

Publications and source records attributed to F Picchio.

8 recordsLinked to original sources

The atrioventricular junction in the univentricular heart: a two-dimensional echocardiographic analysis.

The atrioventricular junction of 40 patients with univentricular heart was evaluated by two-dimensional echocardiography. The apical 4 chamber view optimally imaged the atrioventricular junction, and allowed determination of the type of atrioventricular connection: double inlet, common atrioventricular orifice, and absent right or left atrioventricular connection. When double inlet to 1 ventricle was demonstrated, the 4 chamber view allowed immediate comparison of the form and function of the right and left atrioventricular valves. Because anomalies of the atrioventricular valves frequently complicate the univentricular heart, two-dimensional echocardiographic assessment is a most important adjunct to the preoperative investigation of these patients.

Adolescent

[Transposition of the great arteries: anatomic types of left ventricular outflow tract obstruction (author's transl)].

A postmortem investigation has been carried out in 48 heart specimens with transposition of the great arteries (TGA) to evaluate incidence and type of left ventricular outflow tract obstruction. The frequence of pulmonary stenosis in our series (23%) is similar to those reported from previous studies. Cases have been divided in two groups according to presence or absence of ventricular septal defect. In cases with intact ventricular septum the obstruction was determined by asymmetric hypertrophy of the septum (1 observation) and by abnormal attachement of clefted anterior mitral leaflet to the interventricular septum (2 observations). In the specimens with ventricular septal defect, 4 presented a stenosis due to malalignment of the infundibular septum, associated with valvular stenosis in 1 case and with valvular stenosis and fibrous subvalvular ring in 2. Another case presented a stenotic pulmonary valve and a parachute mitral valve. The remaining 3 showed a cleft of the anterior leaflet of the mitral valve. The high incidence of infundibular malalignment obstruction is underlined together with its association with A-P or L-position of the aorta. This peculiar relation of the great arteries could be angiocardiographically employed as indicative for the presence of this type of left outflow tract obstruction in TGA.

Female

Haemodynamic effects of dobutamine in patients with coronary artery disease.

The haemodynamic effects of the infusion of dobutamine in dosages of 2-5, 5-0 and 10-0 mug/kg/min were studied in twelve patients with coronary artery disease. At the lowest dose, infusion of dobutamine caused a significant increase in cardiac output; greater increases occurred with doses of 5-0 and 10-0 mug/kg/min. The means by which the myocardium produced the increase in cardiac output differed according to the dose of the drug; 2-5 and 5-0 mug/kg/min produced an increase in stroke volume without any significant variation in the heart rate. At the highest dose rate, an increase in heart rate made a distinct contribution to the overall increase in output. The ventricular dp/dt max. increased at all three dosages. Blood pressure, pulmonary arterial and capillary pressure, and left ventricular and diastolic pressure did not show any significant change. The separation of the inotropic and the chronotropic effects of dobutamine according to the infused dose appears to have extremely interesting clinical implications.

Aged

[Origin of 1 of the 2 pulmonary arteries from the ascending aorta. Apropos of 2 surgical cases with 1 being associated with tetralogy of Fallot].

In relation with the report of two cases of branching of one of the pulmonary arteries from the aorta, it was recalled that this is a rare malformation, responsible for a severe cardiac failure with or without cyanosis in the first months of life, intensly suggestive of a left-to-right shunt. Demonstration of surprizing or unhabitual clinical or haemodynamic findings should indicate the performance of a right-sided angiography then an aortography, this being the only way to secure the diagnosis. Combination of such an anomaly with Fallot's tetralogy is exceptional. The clinical diagnosis is made more difficult by the presence of an anastomosis between the pulmonary and the systemic circulations. Only a careful analysis of right angiograms might make it possible to suspect the presence of an abnormal branching of the pulmonary artery, and to perform the aortography. The treatment is surgical in all cases, and should be undertaken early in life, as it is the only way to control the heart failure or to prevent irreversible pulmonary arteriolar lesions.

Aorta