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Biomedical subjects

F Pirk

Publications and source records attributed to F Pirk.

At least 19 recordsLinked to original sources
PubMed1990

[Varices of the colon in the roentgenologic picture].

The authors describe a double contrast X-ray picture of varicosities of the large intestine. In the literature so far irrigoscopic changes specific for varicosities were not described. The authors observed that the defect of the filling increased after Valsalva's manoeuvre. The authors consider this symptom specific for varicosities.

Adult↗
PubMed1985

Primary sclerosing cholangitis. Light and electron microscopy of hepatic tissue in two cases.

In an 18 year-old woman presenting with an intra- and extrahepatic form of sclerosing cholangitis needle biopsy of the liver revealed, in addition to a conspicuous proliferation of biliary ductules and mild inflammatory infiltrations of the portal tract, piece-meal necroses and focal intralobular inflammatory changes. In the second case - a 49-year-old man - presenting with an extrahepatic location of stenoses there were infrequent proliferating biliary ductules in the enlarged fibrotic portal tracts. Ultrastructural investigations revealed in both patients adverse regressive changes in the epithelium of proliferating biliary ductules, seen as microvillous damage on the luminal surface, dilation of the endoplasmic reticulum and mitochondrial swelling; in the second patient there was, moreover, electrondense material in epithelial cytoplasm, probably corresponding to bile components. In the first patient predominated among ultrastructural changes increase of cytoskeletal filaments in some epithelia and pronounced reduplication of the basement membranes of small biliary ducts. These "cholestatic" modifications, expressed in different form in the two patients, were accompanied by dilatation and damage, sometimes total disappearance of microvilli of biliary canaliculi.

Adolescent↗