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Biomedical subjects

F R Bakht

Publications and source records attributed to F R Bakht.

7 recordsLinked to original sources

Toxoplasmosis in pregnancy: an emerging concern for family physicians.

Toxoplasmosis is usually asymptomatic in pregnant women but poses a risk of severe effects on the fetus. One to eight of every 1,000 pregnant women become infected, and the infection is transmitted to the fetus in approximately 40 percent of these cases. The risk of transmission rises with increasing gestational age at the time of initial infection. Congenital infection with toxoplasmosis may lead to serious sequelae, such as blindness, mental retardation, neurologic deficits and deafness. Prevention of morbidity from toxoplasmosis depends on prevention of the infection in pregnant women, plus early recognition and aggressive treatment of maternal infections.

Female↗

Improving measles vaccination rates in previously vaccinated adults.

BACKGROUND: During the 1988 measles epidemic in Houston, Texas, the Harris County Medical Society made each of its members aware of the Centers for Disease Control recommendations concerning revaccination of persons born between 1957 and 1971. A review of records in a family practice residency clinic found a revaccination rate of only 11% among this population. Previous studies of increasing influenza vaccine administration suggest that enlisting the assistance of office personnel can improve the vaccination rate. METHODS: A study was conducted that compared two methods of administering measles vaccine to those born between 1956 and 1967 who had received the killed measles vaccine. Standard ambulatory care (control group) was compared with a proactive system in which front desk personnel and nursing staff identified and vaccinated appropriate patients (study group). RESULTS: Sixty-one percent of the study group were vaccinated after identification by office personnel, compared with 5% of the control group (P less than .001). CONCLUSIONS: Standard ambulatory care protocols, which rely heavily on the patient's chief complaint to determine the patient's medical needs, interfere with the rate of revaccination. The measles vaccination rate can be significantly improved by a simple modification of practice routine, eg, using support personnel.

Adult↗

Naproxen-associated nightmares.

We have reported what we believe to be the first case of naproxen-associated nightmares. Our brief review of basic sleep physiology and the several questions we have raised might help explain this seemingly unusual adverse effect of naproxen.

Adult↗

Postpartum cardiovascular complications after bromocriptine and cocaine use.

A case is presented of a postpartum woman in whom hypertension and pulmonary edema developed after administration of bromocriptine mesylate. Caution is advised when there is additional recent use of cocaine because of a suggested potentiating action of cocaine on the development of adverse cardiovascular and cerebral sequelae in postpartum patients who take bromocriptine.

Adult↗

Therapy for hypercholesterolemia.

For most patients, hypercholesterolemia can be effectively lowered with drug therapy but only after several issues have been considered. First, drug therapy should never be considered without adequate dietary intervention. Dietary therapy may be effective for many patients with mild to moderate elevations in cholesterol. None of the drugs used to treat lipid disorders are benign agents. There is still debate about the interpretations of recent studies, the ability to generalize from studies to the whole population, and the cost effectiveness of drug treatment. Within the framework of the AHA and NCEP guidelines, an individualized approach to therapy is prudent. This should be initiated with maximal patient education because drug therapy will be maintained for the long-term or for life. The LDL and HDL levels, age, sex, other CHD risk factors, cost of treatment, patient awareness, and motivation must all be assessed when making treatment decisions. When drug therapy is considered for patients with isolated hypercholesterolemia, bile acid sequestrants are the drugs of choice.

Anticholesteremic Agents↗

Genitourinary emergencies.

An awareness of pitfalls and perils in diagnosis of traumatic injuries to the genitourinary tract, and indications and contraindications for studies and instrumentation, will help diagnose these sometimes underdiagnosed injuries and help minimize morbidity. Suspicion of testicular torsion should lead to prompt urologic consultation, and priapism also should be promptly treated to preserve function. The treatment of acute urinary retention consists of prompt bladder drainage with attention to etiology and methods.

Emergencies↗