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Biomedical subjects

F R Justiniani

Publications and source records attributed to F R Justiniani.

11 recordsLinked to original sources

Sarcoidosis complicating primary Sjögren's syndrome.

A 60-year-old woman with a 25-year history of primary Sjögren's syndrome developed early sarcoidosis, with asymptomatic hilar and mediastinal lymphadenopathies and non-caseating granulomas; there was spontaneous remission of the lymphadenopathies in one year. The occurrence of sarcoidosis complicating long-standing primary Sjögren's syndrome has not been previously reported. A possible common immunologic abnormality is postulated.

Female↗

Changing prescribing patterns: a program of physician education.

A drug utilization review identified significant inappropriate use of second-generation cephalosporins at a 700-bed community teaching hospital. As a result, an educational program designed to modify physician prescribing patterns was developed as a cost-containment measure. Educational guidelines listing indications and contraindications for cefamandole and cefoxitin and comparing their costs with those of first-generation cephalosporins were placed in patient records, and physician use of these agents was reviewed before, during, and after the intervention. The rate of combined appropriate use of cefamandole and cefoxitin increased from 30 to 58% during the study. A change from the second-generation cephalosporins to therapeutically equivalent, less-expensive drugs was noted in 28% of patients' medical records within 48 hours after placement of the guidelines. This educational program proved to be a low-cost method of successfully altering the prescribing patterns of physicians.

Cephalosporins↗

Charcoal-containing empyema complicating treatment for overdose.

A 25-year-old man was treated with gastric lavage and activated charcoal for alcohol and drug overdose; immediately following the initial treatment he developed tension pneumothorax successfully managed with a chest tube. The patient presented four weeks later with a charcoal-containing empyema, an unreported condition heretofore.

Adult↗