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Biomedical subjects

F R Rodriguez

Publications and source records attributed to F R Rodriguez.

14 recordsLinked to original sources
PubMed1991

A prospective comparison of thromboembolic stockings, external sequential pneumatic compression stockings and heparin sodium/dihydroergotamine mesylate for the prevention of thromboembolic complications in urological surgery.

Deep venous thrombosis and pulmonary emboli are reported to occur in up to 66% of the patients undergoing a major urological operation. Thromboembolic stockings, external sequential pneumatic compression stockings and anticoagulant agents, such as heparin sodium plus dihydroergotamine mesylate, have been suggested to decrease the risk of deep venous thrombosis and pulmonary emboli. A total of 74 evaluable patients undergoing a major urological operation was randomized to receive either thromboembolic stockings, external sequential pneumatic compression stockings, or heparin plus dihydroergotamine as prophylaxis against deep venous thrombosis and pulmonary emboli. 111Indium-labeled platelet scans, performed preoperatively and on days 1, 3 and 6 postoperatively, were used to diagnose deep venous thrombosis and pulmonary emboli. Mean patient age was 63 years and all but 1 operation was performed for neoplastic disease. Deep venous thrombosis was detected in 5 of 25 patients (20%) with thromboembolic stockings, 3 of 24 (12.5%) with external sequential pneumatic compression stockings and 2 of 25 (8%) with heparin plus dihydroergotamine. There was no difference in blood loss or complications among the groups. Although statistical significance among the treatment groups was not reached in this study, the trend to a decrease in deep venous thrombosis and pulmonary emboli with external sequential pneumatic compression stockings and heparin plus dihydroergotamine, and an absence of an increase in morbidity in these groups supports the use of these modalities to decrease the morbidity and mortality of deep venous thrombosis and pulmonary emboli.

Adult↗
PubMed1990

Experience with Duraphase penile prosthesis: its use as replacement device.

The Duraphase Penile Prosthesis is a new, articulating type of semirigid prosthesis which appears to have several advantages over other semirigid penile prostheses. This series describes the experience with this prosthesis in 12 patients and highlights the experience in 4 patients who underwent removal of other types of prostheses due to mechanical or functional problems and replacement with the Duraphase prosthesis. The device has been mechanically reliable during short follow-up, and there has been excellent patient satisfaction.

Aged↗
PubMed1990

Sudden death due to disease flare with luteinizing hormone-releasing hormone agonist therapy for carcinoma of the prostate.

Luteinizing hormone-releasing hormone agonist therapy for prostate cancer is a new method of management for metastatic disease. During the initial 1 to 2-week period of administration an increase in serum testosterone concentration can lead to an exacerbation of clinical symptoms (flare phenomenon). Two patients are summarized who received luteinizing hormone-releasing hormone agonist therapy without flare blockade and died suddenly during month 1 of therapy. A review of 765 patients in 9 series found 10.9% who suffered disease flare and 15 who died during disease flare. Of these 17 patients 12 were similar to our 2. These data suggest that any patient placed on luteinizing hormone-releasing hormone agonist therapy for prostate cancer merits some form of flare blockade during the initial 1 or 2 months of therapy.

Adenocarcinoma↗
PubMed1989

Complete urinary obstruction following periurethral polytetrafluoroethylene injection for urinary incontinence.

We report a unique case of foreign body granulomatous reaction after periurethral polytetrafluoroethylene injection causing complete urinary obstruction. Urinary obstruction in the immediate postoperative period and granuloma formation following polytetrafluoroethylene injection are not unusual. To our knowledge delayed complete urinary obstruction after polytetrafluoroethylene injection has not been described previously in the urological literature.

Aged↗
PubMed1989

Periurethral polytetrafluoroethylene injections for post-prostatectomy incontinence.

Incontinence following prostatectomy is relatively common and produces well-known social and pathologic consequences. Previous reports have shown that periurethral injections of polytetrafluoroethylene (PTFE or Teflon) can provide continence in many patients with a variety of etiologies. Politano's group has shown about 50% of his incontinence radical prostatectomy patients to be cured or improved by these injections. Our experience with 10 patients found that overall, six of 10 were cured or improved. Five of six radical prostatectomy patients were cured or improved after radical prostatectomy and radiation therapy. One patient has subsequently undergone artificial sphincter placement without difficulty. PTFE injections may be a low morbidity procedure for the treatment of post-prostatectomy incontinence and still allow for later artificial sphincter placement if required.

Humans↗
PubMed1988

Salvage radical prostatectomy for adenocarcinoma of the prostate.

Radiotherapy has been a major method of treating localized carcinoma of the prostate. It is becoming increasingly apparent that failures of radiotherapy do occur and can be predicted by postradiation biopsy. Salvage radical prostatectomy can be offered to these patients. The authors report on five patients with residual carcinoma after radiotherapy. Three patients had undergone external-beam radiotherapy and two had undergone interstitial plus external-beam radiotherapy. All salvage radical prostatectomies were uncomplicated technically. One patient had a myocardial infarction believed to be unrelated to the procedure. Two patients, observed for over 1 year, have mild residual stress incontinence but residual adenocarcinoma proved to be localized to the surgical specimen in all but one patient. One patient underwent nerve-sparing radical prostatectomy and has had return of sexual function. Salvage radical prostatectomy is a viable option for patients who have histologically proven residual carcinoma after definitive radiotherapy.

Adenocarcinoma↗
PubMed1988

An evaluation of serial digital rectal examinations in screening for prostate cancer.

The purpose of this review is to test the hypothesis that serial digital rectal examinations of the prostate lead to detection of prostate cancer at an earlier and more curable stage. The clinic records of 4,843 patients between 40 and 79 years old seen at the Brooke Army Medical Center prostate cancer screening clinic between January 1979 and September 1985 were reviewed. Of the patients with palpable nodules 122 were found on biopsy to have adenocarcinoma of the prostate. We compared the clinical and, when possible, pathological stage of disease diagnosed at the initial clinical visit to those from patients who had prior normal digital rectal examinations at the screening clinic and who were followed at our clinic. There was a numerically striking difference in the percentage of patients in each group with clinical as well as pathological stage B cancer. Due to the small number of patients in each group these differences were not statistically significant.

Adenocarcinoma↗
PubMed1987

The impact of cigarette smoking on stage, grade and number of recurrences of transitional cell carcinoma of the bladder.

The records of 386 patients with diagnosed transitional cell carcinoma of the bladder were reviewed to determine a correlation between smoking history, and stage, grade and number of recurrences of transitional cell carcinoma. A significant association was detected between smoking history and all 3 variables. Within this military population 79 per cent of the patients were noted to have a smoking history, which is higher than most previously studied groups. These data further confirm the association between cigarette smoking and transitional cell carcinoma of the bladder, and suggest that cigarette smoking within the military population may portend a much higher cancer risk in this group.

Carcinoma, Transitional Cell↗
PubMed1987

Intravesical alum irrigation for intractable bleeding secondary to adenocarcinoma of the prostate.

We report on 2 patients in whom intractable hematuria was caused by carcinoma of the prostate. Since the hematuria failed to respond to conservative measures, intravesical 1 per cent alum irrigation was used. Hematuria resolved in both patients and no toxicity was observed. Intravesical alum irrigation should be considered in any patient with significant hematuria secondary to carcinoma of the prostate in whom conservative therapy has failed.

Adenocarcinoma↗
PubMed1987

Medullary sponge kidney and congenital hemihypertrophy.

We have presented a case of medullary sponge kidney associated with congenital hemihypertrophy. Evaluation by calcium loading revealed no abnormal handling of this ion. The recognition of this unusual syndrome is important because it appears that other disease processes common to medullary sponge kidney alone or congenital hemihypertrophy alone do not appear with the same frequency when both processes occur simultaneously.

Adult↗