Biomedical subjects

F R Sprague

Publications and source records attributed to F R Sprague.

3 recordsLinked to original sources

PubMed1998

Physician community involvement. Working within your area to promote better health.

How many times have you been asked to participate in a meeting, forum, or task force to address a community health issue in the last few years? Opportunities seem to crop up almost weekly as non-profit organizations acclimate to meet changing needs and health systems continue to adapt to market forces. But participating in ongoing community projects, or even attending periodic meetings, draws time away from practice and professional obligations and limits an already modest supply of personal time. Is involvement in a community collaborative effort worth the time? And, if so, what are the benefits and challenges to physicians, health systems, and communities from this type of investment?

Community Health Services↗

PubMed1981

Oral hydralazine therapy for acute pulmonary embolism and low output state.

Shortly after pelvic surgery, massive bilateral pulmonary emboli and shock developed in an elderly woman. Despite fluids, dopamine hydrochloride, and heparin sodium, her condition steadily deteriorated. Two trials of hydralazine hydrochloride were given and each was associated with pronounced clinical and hemodynamic improvements. Ninety minutes and 24 hours after the first trial, her pulmonary vascular resistance decreased 44% and 67%, respectively, and cardiac index increased 40% and 90%, respectively. There were insignificant changes in heart rate and blood pressure. The hemodynamic improvements reversed when the hydralazine therapy was stopped but improved again during the second trial. Hydralazine may be of substantial benefit to patients with hemodynamic compromise secondary to pulmonary embolism.

Administration, Oral↗

PubMed1975

Genetic analysis of dermatoglyphic patterns in twins.

Analysis of variance was performed on 71 dermatoglyphic variables in 424 twin sets. Using a method of twin analysis estimates of genetic variance were obtained. 54 of the variables were quantitated using a scoring system with modifications of arch or no pattern = 0, loops = 1, whorl = 2. The results indicated a significant genetic influence in most pattern areas. Patterning was more genetically controlled in the hand than in the foot. The hallucal area had the most significant genetic component of the foot while the patterns in the thumb had nonsignificant components of genetic variance. The thumb deviated from patterning in the rest of the fingers and may be more closely related to big-toe patterning.

Dermatoglyphics↗