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Biomedical subjects

F Rampen

Publications and source records attributed to F Rampen.

13 recordsLinked to original sources
PubMed1980

Malignant melanoma: sex differences in survival after evidence of distant metastasis.

Survival data of 106 males and 110 females with disseminated malignant melanoma, recorded between 1956 and 1975, were reviewed. Survival after first evidence of distant metastasis was significantly longer in women than in men (P = 0.02). There was no difference in survival after occurrence of distant metastasis between pre- and postmenopausal women, nor between parous and nulliparous women. However, there was a clear female superiority of premenopausal women over males less than or equal to 50 years and, to a lesser extent, of postmenopausal women over males > 50 years. It is concluded that endocrine factors enhance melanoma activity in the male patient. The suggestion that malignant melanoma is "testosterone-dependent" seems justifiable. A possible explanation is given for the general experience that women with melanoma show a more favourable response to chemotherapy than men.

Female↗
PubMed1978

Venereal syphilis in tropical Africa.

A steady decline in the incidence of positive results to the Kahn test is reported in Malawian patients during the period 1968-75. Other studies have shown that the incidence of early and late syphilis in sub-Saharan Africa has dropped considerably over the past few decades. The number of reported cases of early syphilis in certain urban areas, however, appears to be high. It is suggested that the downward trend in the incidence of syphilis in Africa is related to the increased and often indiscriminate use of penicillin.

Humans↗