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Biomedical subjects

F Reiss

Publications and source records attributed to F Reiss.

At least 19 recordsLinked to original sources

Leukonychia trichophytica caused by Trichophyton rubrum.

A case of leukonychia is reported, in which Trichophyton rubrum was isolated from the nail plates and interdigital spaces of the toes. Treatment consisted of oral griseofulvin, which produced appreciable improvement after ten months' therapy.

Fingers↗

Immunization of mice with a mutant of Cryptococcus neoformans. Characterization of the mutant, actively acquired resistance to experimental cryptococcosis in mice.

In 69% of subdermally and 50% of subcutaneously immunized mice, immunity against Cryptococcus neoformans was obtained. The vaccine consisted of a gamma-irradiated mutant, which grew well at 5 degree C and at room temperature. Many subcultures and animal passages did not restore this mutant to the encapsulated, pathogenic wild type.

Animals↗

Immunological studies of the anticryptococcal factor of normal human serum.

Preliminary studies have shown a very high inhibitory activity in the alpha2 and gamma zone of human serum towards the growth of Cryptococcus neoformans. These findings are now corroborated by single radial immunodiffusion tests, which showed the some loss of IgA and IgM globulins and of the other three globulin fractions (ceruloplasmin, alpha2 macroglobulin and alpha2 HS glycoprotein) which migrate in the alpha2 zone. The data was obtained by single radial immunodiffusion tests. The losses were not statistically significant however. No change in the immunoglobulin content of the sera kept for 6 days in contact with a heat-killed suspension of C. neoformans was noted. These findings suggest, that the inhibitory activity of the normal human serum on the in-vitro growth of C. neoformans is due to the above mentioned globulin fractions and not to a single specific factor.

Antibodies, Fungal↗