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Biomedical subjects

F Remy

Publications and source records attributed to F Remy.

At least 19 recordsLinked to original sources
PubMed2006

[Long-term behavior of ankle fusion: assessment of the same series at 7 and 23 year (19-36 years) follow-up].

PURPOSE OF THE STUDY: Theoretically, long-term functional and radiographic degradation is predictable after ankle fusion, but sound evidence from the consecutive analysis of the same cohort is lacking. The purpose of this study was to check the hypothesis by repeating assessment in the same cohort of patients who underwent ankle fusion. MATERIAL AND METHODS: The cohort included 52 ankle fusions which had been analyzed in 1984 at seven years (range 2-22 years) follow-up then again in 2000 using the same evaluation criteria. Among the 52 patients, six were lost to follow-up (11.5%) 20 had died (38.4%) and one had undergone leg amputation. The second analysis thus included 25 patients (48%). The comparison cohort thus included 25 patients (18 men and 7 women), mean age 62+/-12.6 years (range 40-94) at the 2000 assessment performed 23+/-4.5 years (range 19-36 years) after the fusion. Functional outcome was assessed with the 100-point Duquennoy scale. Osteoarthritis of the subtalar and mediotarsal joints were assessed preoperatively and at follow-up using the same scale. RESULTS: The functional outcome did not deteriorate significantly between 1984 and 2000. The mean score was 65.8+/-22.6 (range 19-92) in 1984 and 64.7+/-18.3 (range 34-90) in 2000 (p=0.67). Fifteen patients (60%) had a good or very good outcome at seven years, and 14 (56%) at 23 years. Between 1984 and 2000, ten patients improved their score (on average 10.4 points, range 1-21 points), two had an unchanged score and thirteen a lower score (on average 10 points, range -1 to -24). Ten of these thirteen patients developed severe intercurrent conditions (neurological or cardiac) explaining the degradation. At last follow-up, sixteen ankles were pain free or nearly pain free. Twelve patients considered their ankle as a forgotten problem (VAS 10) and had no regrets concerning the operation. The evolution of the subtalar joint in 16 cases (nine fusions including five at the same time as the ankle fusion and four performed within four years) showed that all developed osteoarthrtic degradation early with aggravation between 1984 and 2000, leading in the majority of cases to severe degenerative disease. This osteoarthritis was painful in less than one-third of the cases (including the four secondary subtalar fusions and the four subtalar fusions which were painful at mobilization). Twenty-three mediotarsal joints were analyzed (two fusions four years after ankle fusion). The degradation was later and less severe than for the subtalar joint with a majority showing moderate osteoarthritis. Ten ankles exhibited compensatory hypermobility of the forefoot measured at more than 15 degrees without pain. DISCUSSION: This long-term follow-up with two successive assessments using the same evaluation criteria did not demonstrated the late degradation of function expected after ankle fusion. It did show however the presence of undeniable radiographic degradation of the subtalar joint but with little or no severe clinical expression at a minimal follow-up of 19 years. There was no need for complementary fusion between 4 and 23 years follow-up.

Adult↗
PubMed2006

[Water supply for Peking ducks--possible alternatives for bathing].

In order to investigate possible advantages of open water drinkers such as troughs and bells in the intensive husbandry of ducks, we evaluated in this study the effect of open water systems on the behavior and health of peking ducks. In this investigation six fattening trials each with 1152 Cherry Valley Peking ducks were analyzed. The average fattening period was 47 to 49 days. The ducks were kept on straw in six standardized compartments each 32 qm with 192 ducks. 25% of the compartment with perforated grid, with one of the tested water systems. In contrast to pens with nipple-drinkers only, the ducks in pens with open water troughs/showers had the opportunity to exhibit their natural drinking behavior and water associated activities in accordance with the animal welfare requirements. In the free-choice pens the open water systems were significantly preferred, and over a 24-hour period the ducks in watering areas with open water troughs showed higher activity. Limiting the access to the open water systems to eight, four or two hours per day led to an increased use per time unit. Ducks with access to nipple drinkers only showed a significantly higher percentage of plugged up nostrils than animals from pens with open water drinkers. Open water drinkers had also a positive impact on the plumage condition.

Animal Husbandry↗
PubMed2001

[Anterior iliopsoas impingement after total hip arthroplasty: diagnosis and conservative treatment in 9 cases].

PURPOSE OF THE STUDY: Impingement of the iliopsoas muscle due to a protruding acetabular component is an uncommon cause of pain after total hip arthroplasty. Diagnostic signs may be misleading and therapeutic management has varied, leading to divergent findings reported in the literature. The purpose of this prospective work was to determine the frequency of groin pain due to iliopsoas impingement (with or without an identified causal mechanism) in patients with painful total hip arthroplasties and to identify diagnostic criteria that can be used to determine the appropriate therapeutic strategy. MATERIAL AND METHODS: This prospective study was conducted between 1998 and 2000 and included 206 painful total hip arthroplasties. From this series, we excluded cases where pain was related to loosening (139 cases, 67%), infection (45 cases, 21.7%), bursitis on trochanteric sutures (2 cases, 1%), and aortic aneurysm with gluteal claudication and resulting from a lumbosacral disorder (10 cases, 4.8%). This left 9 cases (4.3%) with a clinical picture suggestive of iliopsoas impingement. These 9 patients (mean age 50 years, age range 38 - 65) had 8 uncemented press-fix cups and 1 cemented cup with an acetabular mesh. Mean delay to the development of pain after the arthroplasty procedure was 7.3 months (1 - 48 months). The most suggestive clinical sign was groin pain triggered by active flexion of the hip and flexion of the hip against force with a painful arc measuring 30 degrees to 70 degrees. None of these 9 patients had any sign of material loosening and puncture aspiration ruled out infection. The final diagnosis was confirmed by sedation of pain after extra-articular infiltration at the anterior border of the cup (overhanging cup in 6/9 cases) under computed tomographic guidance. RESULTS: Infiltrations with xylocaine and long-release corticosteroids led to complete sedation of pain in 4 out of 9 patients and partial sedation in 1 other. Recurrent pain led to terminal tenotomy of the iliopsoas in 4 patients, that provided total sedation in 3 and partial sedation in 1. In all, successful pain relief was achieved in 7 out of 9 cases: 4 after infiltration (repeated in 1 cases) and 3 after tenotomy. At last follow-up physical examination has not identified any loss of flexion force. DISCUSSION AND CONCLUSION: Irritation of the iliopsoas muscle can be the cause of pain in 4.3% of patients experiencing pain after total hip arthroplasty. The delay to symptom onset is variable but there appears to be a pain-free period after implantation. An anatomic element (anterior cup overhang) is not necessary for diagnosis since the infiltration test was positive in 1 out of 3 cases without any identified acetabular factor. The infiltration test is an important element for positive diagnosis and should be the first therapeutic measure taken. We achieved success in 4 out of 9 cases. Tenotomy is indicated in case of recurrence, providing complete cure in 3 out of 4 cases in our series. Cure may be achieved without changing the cup by simple infiltration or tenotomy of the iliopsoas that led to complete cure in 7 out of 9 cases in our series, even in patients with an overhanging cup (6 out of 9 cases). An elective procedure might be indicated if a specific anomaly is identified (overly long screw, cement leakage) or for a screwed cup. The infiltration test should however be performed beforehand to confirm the diagnosis.

Adrenal Cortex Hormones↗
PubMed2000

The VUV Absorption Spectrum of Lead Monoxide.

The VUV absorption spectrum of PbO vapor down to 300 Å has been observed for the first time. Four ionization energies have been determined from Rydberg series at 8.73, 8.83, 12.81, and 26.28 eV corresponding to the X(2)Pi, A(2)Sigma(+), B(2)X(+), and C(2)Sigma(+) electronic states of the PbO(+) ion. Copyright 2000 Academic Press.

Journal Article↗
PubMed2000

FT Infrared Spectra of FCN from 1200 to 1800 cm(-1) and from 2800 to 7000 cm(-1) and Global Rovibrational Analysis of the Main Isotopomers.

We measured the FT spectrum of natural FCN from 1200 to 1800 cm(-1) and from 2800 to 7000 cm(-1) with a near Doppler resolution and a line-position accuracy between 1 and 8 x 10(-4) cm(-1). Lines were assigned to 91 different bands (75 of (19)F(12)C(14)N, 11 of (19)F(13)C(14)N, and 5 of (19)F(12)C(15)N), of which no more than five had been previously reported at lower resolution. From band-by-band analyses we deduced effective state parameters. As those results complete the study of the Fourier transform spectra of natural cyanogen fluoride from 1200 to 7000 cm(-1), global rovibrational analyses of (19)F(12)C(14)N, (19)F(13)C(14)N, and (19)F(12)C(15)N have been performed on the basis of all the available experimental data about their rovibrational energies. We have so determined sets of about 100 molecular parameters for each isotopomer, and a statistical agreement was obtained. A labeling of the vibrational states is proposed on the basis of the eigenvector coefficients. Copyright 2000 Academic Press.

Journal Article↗
PubMed1999

The VUV Absorption Spectra of SiF and SiF+

The absorption spectrum of a microwave discharge (2450 MHz) in flowing helium with traces of SiF4 has been recorded on the SA61 beam line of SUPERACO between 2000 and 500 Å. Two new ionization energies have been observed at 15.12 and 17.27 eV corresponding, respectively, to the A1Pi and B1Sigma+ states of SiF+. The A1Pi <-- X1Sigma+ transition of the ion has been identified for the first time on high-resolution spectra obtained in 1992 with the 35-foot Eagle spectrograph in Meudon. Copyright 1999 Academic Press.

Journal Article↗
PubMed1999

Rydberg States of SiCl.

A fluorescence spectrum, excited by the synchrotron radiation of Superaco in a microwave discharge through He + SiCl(4), leads to the observation of five new electronic states of SiCl, converging to the ground X(1)Sigma(+) state of the SiCl(+) ion. The (n s varsigma) and (n p pi) Rydberg series are extended respectively to n = 6 and n = 7. A new ionization limit is observed in absorption at 11.238 eV corresponding to the a(3)Pi electronic state of SiCl(+). Four new states are observed which converge to that limit. Copyright 1999 Academic Press.

Journal Article↗
PubMed1999

The VUV Absorption Spectrum of the GeO Molecule.

The absorption spectrum of GeO, between 2000 and 300 Å, was recorded using the facilities of the SUPERACO synchrotron radiation in Orsay, France. The first three ionization limits, corresponding to the X(2)Sigma(+), A(2)Pi, and B(2)Sigma(+) states of the GeO(+) ion, were confirmed at 11.2814, 11.42, and 15.048 eV, respectively. The fourth ionization limit corresponding to the C(2)Sigma(+) ionic state was measured for the first time at 31.47 eV, in reasonable agreement with theoretical calculations. Copyright 1999 Academic Press.

Journal Article↗
PubMed1999

[Retrospective study of 23 arthrolyses of the elbow for post-traumatic stiffness: result predicting factors].

INTRODUCTION: The goal of the study was to determine the results of elbow arthrolysis for post-traumatic stiffness, and to identify factors governing the result of that procedure. PATIENTS AND METHODS: Between 1984 and 1997, 26 elbow arthrolysis were performed. Twenty-three patients were retrospectively assessed by an independent examiner, 3 patients were lost for follow-up. The mean age at surgery was 41 years. The traumatisms responsible for stiffness were: 5 elbow dislocations, 7 radial head fractures, 3 olecranon fractures, 8 humeral palette fractures. The surgical approach was 2 times posterior, 9 times lateral, 12 times combined (posterior and lateral). The surgical approach was chosen according to the preoperative analysis of the stiffness factors and the scars in case of previous surgery. RESULTS: At follow-up (85 months (12-144)), 5 patients were very satisfied, 17 patients were satisfied and one patient was not satisfied. Six patients had discomfort in daily gesture. Ten patients had no pain, 6 had pain while effort and 7 had climatic pain. Two ulnar palsies existing at arthrolysis did not improve after neurolysis and anterior ulnar nerve transposition. Range of motion increased in every sector of mobility, and at follow-up mean ROM was: 121 degrees flexion, -31 degrees extension, 69 degrees pronation and 65 degrees supination. The average absolute benefit in flexion-extension was about 38 degrees. The average relative (flexion-extension) benefit according to Merle d'Aubigné was about 44%. At follow-up, the average pronation-supination was higher than 100 degrees. The range of motion was not correlated to the type of injury, to the surgical management, nor to the type of rehabilitation program. Likewise, the delay between traumatism and arthrolysis had no influence on the result. On the other hand, the range of motion was directly correlated to the preoperative mobility and mobility obtained just after surgery (p = 0.001). However, the range of motion at follow-up was slightly decreased (5 degrees to 15 degrees) compared to the mobility obtained just after surgery. DISCUSSION: The final range of motion was mainly related to the severity of the preoperative stiffness. We noticed that few patients were bothered in daily gestures, in spite of a relative stiffness. The type of injury did not seem to influence the final result. Elbow arthrolysis remains a mobilizing technique giving reliable long-lasting results. CONCLUSION: The range of motion obtained after arthrolysis performed because of elbow post-traumatic contracture is mainly related to preoperative stiffness. By comparing with postoperative range of motion, a loss of 5 degrees to 10 degrees can be predicted.

Adult↗
PubMed1998

The VUV Absorption Spectrum of the Tin Monoxide Molecule

The absorption spectrum of heated SnO between 2000 and 300 A has been recorded using the facilities of the SuperACO synchrotron at Orsay, France. New bands have been observed which supplement the data on the previously known systems of SnO. Newly discovered Rydberg series have confirmed the four ionization potentials observed or calculated by Dyke et al. (1982. Chem. Phys. 67, 245). Copyright 1998 Academic Press. Copyright 1998Academic Press

Journal Article↗
PubMed1998

[Reproducibility of the radiographic analysis of dysplasia of the femoral trochlea. Intra- and interobserver analysis of 68 knees].

PURPOSE OF THE STUDY: The relation between patello-femoral instability and trochlear dysplasia was identified by Dejour. Trochlear dysplasia, diagnosed on knee lateral Xray when the trochlear groove crosses both femoral condyles (the so-called "crossing sign"), must be corrected to improve patello-femoral stability. However surgery should be related to the severity and the shape of trochlear dysplasia, underlining the importance of a reproducible classification. The aim of this study was to establish intra and inter-observer reliability of Dejour's radiographic criteria. MATERIAL: 68 preoperative exact knee profile radiographs were harvested from clinical records of 64 patients who underwent trochleoplasty because of patello-femoral instability and trochlear dysplasia. On these 68 views, the crossing sign was identified by the senior surgeon (F.G.) who performed or supervised surgery. METHOD: The 68 radiographs were examined independently by 7 observers (2 juniors, 5 seniors) in order to assess interobserver agreement. Two juniors repeated the observation to test intraobserver agreement. Reproducibility for categorical data (7 shapes of trochlea according to Dejour (3 for dysplasia)) was evaluated by Kappa statistics, and for numerical data (depth and anterior projection of the trochlear groove with respect to anterior femoral cortex) we used the interclass correlation analysis. RESULTS: Two out of the 7 observers rated all the 68 trochleas as dysplastics. The 5 others rated as normal 1 to 6 trochleas out of the 68. None of the 68 trochleas were recognized with the same shape by the 7 examiners. At best, 6 observers agreed on the same shape and for only 12 trochleas. Disagreement was mostly related to mistakes between type I and type II of dysplasia. For trochlear morphology interobserver agreement was slight (Kappa = 0.17) and intraobserver agreement was fair (Kappa = 0.3). The mean prominence of the trochlea was 3 +/- 2.1 mm [-6 to 10], and the mean trochlea depth was 1 +/- 1.9 mm [0 to 11]. These measurements were more reliable since the interclass correlation coefficients were respectively 0.62 and 0.38. The level of experience of the observers had no influence for categorical or numerical data. DISCUSSION: Our results indicated a low interobserver agreement for trochlear shape identification according to Dejour. The most reliable criteria was measurement of the trochlear prominence which was mostly pathological in our series. The "crossing sign" was reliable to diagnose dysplasia since the probability to rate as normal a true dysplastic trochlea was only 3.1 per cent. However, once the dysplasia diagnosed, this classification gave inconsistent results to select the trochlear shape, particularly for type II. To improve reproducibility we propose to diagnose a type II only when 5 millimeters separate the crossings between the medial and lateral condyles. CONCLUSION: We recommend to use anterior projection of the trochlear groove to rate trochlear dysplasia and to determine the adequate type of trochleoplasty: elevating of the lateral facet if non prominent or deepening of the groove when prominent.

Adolescent↗
PubMed1995

Plasma cell proliferation in monoclonal gammopathy: relations with other biologic variables--diagnostic and prognostic significance.

PURPOSE: We investigated the place of direct plasma cell proliferation analysis beside other biologic data in monoclonal gammopathy, particularly the serum level of C-reactive protein (C-RP) PATIENTS: Eighty patients were studied at the time of their diagnosis. Patients with a serum creatinine level greater than 200 mumol/L were excluded. METHODS: Plasma cell proliferation analysis was performed after bromodeoxyuridine incorporation and double immunoenzymatic labeling on cytological smears, making determination of the plasma cell labeling index (LI) possible. The other biologic variables studied were related to tumor burden (plasmacytosis, hemoglobin, serum levels of monoclonal immunoglobulin, albumin) or to kidney function (creatinine). beta 2-microglobulin (beta 2-M), C-RP, lactic dehydrogenase (LDH), and calcemia were also assessed. RESULTS: No correlation was found between LI and serum C-RP. LDH was the sole variable significantly correlated to C-RP (P < 0.01). Besides the biologic parameters used for the staging according to the Durie and Salmon classification, beta 2-M, albumin and LI were significantly different between stages (P < 0.0002, < 0.0004, < 0.00001). LDH and C-RP showed no significant difference. Results were similar when patients with and without bone lesions were analyzed separately. Multivariate analysis ranked these variables as follows with respect to prognostic value: beta 2-M, LI, and age. CONCLUSION: Among the variables analyzed, LI is the sole true reflector of cell proliferation. We confirm its diagnostic and prognostic value.

Adult↗
PubMed1994

A preliminary chemotaxonomic review of Kopsia (Apocynaceae).

The present paper is the result of a botanical and chemical study of the Indo-Pacific genus Kopsia (Plumerioideae-Rauvolfieae) Apocynaceae. Some of the species of this genus possess medicinal uses. A survey of the accepted taxa and their synonymy, based on the study of types, is presented. Studies on alkaloids provides chemotaxonomic information. Indeed, in some cases, chemical relationships occur between species belonging to the same botanical group.

Alkaloids↗
PubMed1994

Fluorescence image analysis of plasma cells in monoclonal gammopathies.

The DNA content of plasma cells was estimated by fluorescence image analysis in monoclonal gammopathies. Image analysis provides the possibility of measuring the bone marrow plasma cell population separately from the other myeloid cells. Plasma cells were labeled, identified and then relocated for propidium iodide intensity measurements. Patients with DNA malignancy grade > 0.20 or with DNA index > 1.15 had a poorer survival rate than did patients with a low DNA malignancy grade or DNA index. DNA malignancy grade is based on the variance of DNA values around the normal diploid peak, as proposed by Böcking. Of all the biologic and clinical parameters investigated, the serum beta 2 microglobulin level was the most important prognostic factor for survival in the multivariate regression analysis, and the DNA entropy index provided the most significant additional information.

Aged↗
PubMed1993

Flavonone and chalcone derivatives from Cryptocarya kurzii.

Four complex flavanones, kurziflavolactones A [2], B [3], C [4], and D [5] and a complex chalcone 6 with an unprecedented carbon side chain on the flavanone or chalcone A ring have been isolated from a Malaysian plant, Cryptocarya kurzii (Lauraceae). Their structures were determined by extensive spectroscopic analysis, especially 2D nmr experiments. Compounds 3 and 6 showed slight cytotoxicity against KB cells, with IC50 values of 4 and 15 micrograms/ml, respectively. A biosynthetic pathway for the formation of these compounds is suggested.

Antineoplastic Agents, Phytogenic↗